884 Matching Annotations
  1. Nov 2018
  2. europepmc.org europepmc.org
    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
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    europepmc.org/articles/PMC5941622/
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    GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death
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    sciencedirect.com/science/article/pii/S2451945617304233
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    Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH
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    academic.oup.com/endo/article/159/5/2165/4960919
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    The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity
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    sciencedirect.com/science/article/pii/S1931312818301392
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14310
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    CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR‐ABL‐positive cells
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26599
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    EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
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    sciencedirect.com/science/article/pii/S1097276518302211
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    Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC5828296/
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    c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling
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    sciencedirect.com/science/article/pii/S1535610817305664
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    Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity
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    sciencedirect.com/science/article/pii/S1074761318300062
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    Arctic Aβ40 blocks the nicotine-induced neuroprotective effect of CHRNA7 by inhibiting the ERK1/2 pathway in human neuroblastoma cells
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    sciencedirect.com/science/article/pii/S0197018617304278
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    An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC5840776/
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    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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    sciencedirect.com/science/article/pii/S2405471218300541
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    Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling
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    academic.oup.com/endo/article-abstract/159/4/1547/4828198
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    Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA
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    sciencedirect.com/science/article/pii/S0092867417314307
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    Origins and Specification of the Drosophila Wing
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    sciencedirect.com/science/article/pii/S0960982217314689
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    OsMAPK3 Phosphorylates OsbHLH002/OsICE1 and Inhibits Its Ubiquitination to Activate OsTPP1 and Enhances Rice Chilling Tolerance
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    The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity
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    nature.com/articles/s41598-018-20911-2
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    β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
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    Hyperinnervation improves Xenopus laevis limb regeneration
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    sciencedirect.com/science/article/pii/S0012160617302476
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    Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor
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    sciencedirect.com/science/article/pii/S0092867417313880
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    Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)
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    CK2 oppositely modulates L-DOPA induced dyskinesia via striatal projection neurons expressing D1- or D2-receptors
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    jneurosci.org/content/37/49/11930
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    Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.
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    FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
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    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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    europepmc.org/articles/PMC5734934/
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    Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
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    sciencedirect.com/science/article/pii/S1535610817304646
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    Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling
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    link.springer.com/article/10.1007/s12640-017-9839-1
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  34. europepmc.org europepmc.org
    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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    europepmc.org/articles/PMC5655547/
  35. Nov 2017
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development
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    ncbi.nlm.nih.gov/pmc/articles/PMC5599238/
  37. academic.oup.com academic.oup.com
    Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway
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    academic.oup.com/endo/article/158/10/3200/3979717/Carbon-Black-Nanoparticles-Inhibit-Aromatase
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    Protease activated receptor 2 controls myelin development, resiliency and repair
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    onlinelibrary.wiley.com/doi/10.1002/glia.23215/full
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    A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
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    sciencedirect.com/science/article/pii/S1550413117304904
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    Endogenous, Regulatory Cysteine Sulfenylation of ERK Kinases in Response to Proliferative Signals
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    sciencedirect.com/science/article/pii/S0891584917307347
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    Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14081/full
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    Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action
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    sciencedirect.com/science/article/pii/S1074761317303199
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    GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia
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    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24119/full
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    Intra‐prelimbic cortical inhibition of striatal‐enriched tyrosine phosphatase suppresses cocaine seeking in rats
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    onlinelibrary.wiley.com/doi/10.1111/adb.12504/full
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    Neurodegenerative effects of azithromycin in differentiated PC12 cells - ScienceDirect
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    sciencedirect.com/science/article/pii/S0014299917303084
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    Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization
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    sciencedirect.com/science/article/pii/S0306452217304967
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    Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells - ScienceDirect
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    sciencedirect.com/science/article/pii/S1044743116302603
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    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
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    sciencedirect.com/science/article/pii/S1535610817302519
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    EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis
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    academic.oup.com/jes/article/1/2/127/2930778/EGFR-Induces-E2F1-Mediated-Corticotroph
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    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
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    elifesciences.org/articles/26362
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    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
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    jneurosci.org/content/37/7/1772
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    Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues
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    academic.oup.com/endo/article/158/5/1217/2908842/Follistatin-Targets-Distinct-Pathways-To-Promote
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    Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet–Induced Obesity
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    academic.oup.com/endo/article/158/6/1634/3829915/Reg2-Expression-Is-Required-for-Pancreatic-Islet
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    A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women
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    academic.oup.com/endo/article/158/1/84/2751114/A-Potential-Role-for-Endoplasmic-Reticulum-Stress
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC5367084/
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    Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain
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    ncbi.nlm.nih.gov/pmc/articles/PMC5399753/
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    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    elifesciences.org/content/6/e22871
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    YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
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    elifesciences.org/content/6/e22416
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    Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression
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    Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling
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    FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms
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    A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination
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    Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
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    Multivalent Small-Molecule Pan-RAS Inhibitors
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    Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
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    Consolidation of Goal-Directed Action Depends on MAPK/ERK Signaling in Rodent Prelimbic Cortex
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    jneurosci.org/content/36/47/11974
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    A Rapid Induction Mechanism for Lin28a in Trophic Responses
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    Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
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    Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII
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    ncbi.nlm.nih.gov/pmc/articles/PMC5218530/
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    Glutamatergic neurotransmission in the prefrontal cortex mediates the suppressive effect of intra-prelimbic cortical infusion of BDNF on cocaine-seeking
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    sciencedirect.com/science/article/pii/S0924977X16308483
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    Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
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    ncbi.nlm.nih.gov/pmc/articles/PMC5127645/
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    SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer
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    sciencedirect.com/science/article/pii/S2352396416303632
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    Protein kinase Cɛ activity regulates mGluR5 surface expression in the rat nucleus accumbens
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23868/full
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    Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model
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    Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23622/full
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    Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC4145180/
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    Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC4107404/
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    Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function
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    onlinelibrary.wiley.com/doi/10.1111/jnc.13038/full
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    Regulation of Neuronal Gene Expression and Survival by Basal NMDA Receptor Activity: A Role for Histone Deacetylase 4
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    ncbi.nlm.nih.gov/pmc/articles/PMC4228135/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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    ncbi.nlm.nih.gov/pmc/articles/PMC4160779/