3,752 Matching Annotations
  1. Jun 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Synaptic activity causes minute-scale changes in BAF complex composition and function
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    sciencedirect.com/science/article/pii/S1097276525004563
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    Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117018/
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    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002332
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    Targeting IDH2 promotes antitumor immunity through epigenetic activation of cGAS-STING pathway
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    sciencedirect.com/science/article/pii/S0169500225005033
  8. May 2025
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    Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity
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    sciencedirect.com/science/article/pii/S2211124725005376
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    hnRNPL phase separation activates PIK3CB transcription and promotes glycolysis in ovarian cancer
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    nature.com/articles/s41467-025-60115-7
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    IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner
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    sciencedirect.com/science/article/pii/S193459092500181X
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    GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration
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    sciencedirect.com/science/article/pii/S0896627325003459
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    Direct Arp2/3-vinculin binding is required for pseudopod extension, but only on compliant substrates and in 3D
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    sciencedirect.com/science/article/pii/S2589004225008843
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    Machine-learning-assisted universal protein activation in living mice
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    sciencedirect.com/science/article/pii/S0092867425005173
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    HBV sequence integrated to enhancer acting as oncogenic driver epigenetically promotes hepatocellular carcinoma development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12096768/
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    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
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    Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases
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    pmc.ncbi.nlm.nih.gov/articles/PMC12086040/
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    IMPDH inhibition induces DNA replication stress and ATR sensitivity in Merkel cell carcinoma
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    sciencedirect.com/science/article/pii/S2589004225008284
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    PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation
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    sciencedirect.com/science/article/pii/S2211124725005066
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    Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway
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    sciencedirect.com/science/article/pii/S2211124725005042
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    CapdevilaCastillo_columbia_0054D_18600-html.html
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    SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017769/
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    Division of labor among H3K4 methyltransferases defines distinct facets of homeostatic plasticity
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    sciencedirect.com/science/article/pii/S2211124725005170
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    AHCYL1 mediates the tumor-promoting effect of PREX2 in non-small cell lung carcinoma
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    thno.org/v15p5772.htm
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    Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045047/
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    Profiling triple-negative breast cancer-specific super-enhancers identifies high-risk mesenchymal development subtype and BETi-Targetable vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12070678/
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    Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression
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    sciencedirect.com/science/article/pii/S2211124725004449
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    CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12076484/
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    Proteomics Analysis of the TDP-43 Interactome in Cellular Models of ALS Pathogenesis
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70079
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    Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans
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    The evolution of AKAPs and emergence of PKA isotype selective anchoring determinants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12083921/
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    Dynamic activation of rAAV transgene expression by a small molecule that recruits endogenous transcriptional machinery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12038400/
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    Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates
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    pmc.ncbi.nlm.nih.gov/articles/PMC11809316/
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    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12033352/
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    MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p97/VCP is required for piecemeal autophagy of aggresomes
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    Inherited deficiency of DIAPH1 identifies a DNA double strand break repair pathway regulated by γ-actin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12078678/
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    Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032206/
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    Programmable protein stabilization with language model-derived peptide guides
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997201/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IKAROS levels are associated with antigen escape in CD19- and CD22-targeted therapies for B-cell malignancies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019336/
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    Novel Approaches to 3D Cancer Heterospheroid Culture and Assay Development for Immunotherapy Screening
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    sciencedirect.com/science/article/pii/S0014482725002009
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    1-s2.0-S2589004225008168-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984406/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SNX17 mediates STAT3 activation to promote hepatocellular carcinoma progression via a retromer dependent mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035908/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LCMR1 deficiency exacerbates LPS‑induced lung injury in lung‑on‑a‑chip and mouse models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12076286/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12030902/
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    NID2 Affects Prognosis of Glioma via Activating the Akt Signaling Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12028320/
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    Regulatory T Cell Mimicry by a Subset of Mesenchymal GBM Stem Cells Suppresses CD4 and CD8 Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12026101/
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    Suppression of Ovarian Cancer Cell Proliferation Is Associated with Upregulation of Cell-Matrix Adhesion Programs and Integrin-β4-Induced Cell Protection from Cisplatin
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    ALDH1A3 Regulates Cellular Senescence and Senescence-Associated Secretome in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11987895/
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    Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12021886/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration
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    Multi-omics landscape of alternative splicing in diffuse midline glioma reveals immune- and neural-driven subtypes with implications for spliceosome-targeted therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12040961/
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    The suppressive role of GLS in radiosensitivity and irradiation-induced immune response in LUAD: integrating bioinformatics and experimental insights
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    pmc.ncbi.nlm.nih.gov/articles/PMC12040943/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CLEC12A-directed immunocytokine with target cell–restricted IL-15 activity for treatment of acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11983603/
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    RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12075365/
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    SAMHD1 knockout hiPSC model enables high lentiviral transduction efficiency in myeloid cell types
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    pmc.ncbi.nlm.nih.gov/articles/PMC12009803/
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    Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11994622/
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    TurboID Labeling and Analysis of Proteins in the Primary Cilium
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067308/
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    Aryl Hydrocarbon Receptor (AHR) is required for repopulation of decellularized intestinal colon scaffolds
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    pmc.ncbi.nlm.nih.gov/articles/PMC12062895/
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    A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005537/
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    A multi-strategy antimicrobial discovery approach reveals new ways to treat Chlamydia
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    Bisphenol S Exposure and MASLD: A Mechanistic Study in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077661/
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    A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct
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    pmc.ncbi.nlm.nih.gov/articles/PMC12062070/
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    Innovative evaluation of selinexor and JQ1 synergy in leukemia therapy via C-MYC inhibition
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    TPX2 promotes papillary renal cell carcinoma progression by forming a ceRNA with LINC00894
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036302/
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    The mechanisms of HER2 targeted ADCs are dependent on Rab GTPases
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035104/
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    Reshaping the chromatin landscape in HUVECs from small-for-gestational-age newborns
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    pmc.ncbi.nlm.nih.gov/articles/PMC12038915/
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    ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in non–small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077904/
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    Targeting legumain-mediated cell-cell interaction sensitizes glioblastoma to immunotherapy in preclinical models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077903/
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    LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046326/
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    TNF inhibits NKCC2 phosphorylation by a calcineurin-dependent pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048884/
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    PDZ domains of PATJ facilitate immunological synapse formation to promote T cell activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12060881/
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    RAB5 is a host dependency factor for the generation of SARS-CoV-2 replication organelles
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077180/
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    Implementing complex nucleic acid circuits in living cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12042877/
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    Inhibition of placental trophoblast fusion by guanylate-binding protein 5
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057675/
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    Engineering Chromosome Bridges Through CRISPR/Cas9 to Decipher the Impact of Intercentromeric Distance on Resolution Dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057592/
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    Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ubiquitylation of DDX6
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    pmc.ncbi.nlm.nih.gov/articles/PMC12069581/
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    SIRT5-mediated desuccinylation of PPA2 enhances HIF-1alpha-dependent adaptation to hypoxic stress and colorectal cancer metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048626/
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    HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048643/
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    KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12064679/
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    SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12069715/
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    A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12056172/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044007/
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    Feedback-responsive cell factories for dynamic modulation of the unfolded protein response
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