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Apr 2022
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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

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Genetic instability from a single S phase after whole-genome duplication

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ncbi.nlm.nih.gov/pmc/articles/PMC8986533/
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MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

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aacrjournals.org/cancerrescommun/article/2/3/182/694085/MYCMI-7-A-Small-MYC-Binding-Compound-that-Inhibits
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Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide

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  ATCCCCL-247
  
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Tumor targeting with bacterial Shiga toxin B-subunit in genetic porcine models for colorectal cancer and osteosarcoma

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aacrjournals.org/mct/article/21/4/686/689560/Tumor-Targeting-with-Bacterial-Shiga-Toxin-B
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BPS Publications

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  DOI: 10.1111/bph.15763
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763
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A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

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ncbi.nlm.nih.gov/pmc/articles/PMC8971416/
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Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B

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1. scibot 01 Apr 2022
  
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  DOI: 10.18632/aging.203924
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
Mar 2022
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Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity

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1. scibot 26 Mar 2022
  
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  DOI: 10.7150/ijbs.68484
  
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ijbs.com/v18p1912.htm
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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

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Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer

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1. scibot 18 Mar 2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8920231/
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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

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ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com

Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression

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  DOI: 10.1186/s12967-022-03308-8
  
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translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03308-8
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Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: potential role of ADAM9

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  DOI: 10.1002/ijc.33947
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33947
Feb 2022
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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

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1. scibot 21 Feb 2022
  
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  DOI: 10.1038/s41419-022-04564-8
  
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nature.com/articles/s41419-022-04564-8
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Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

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1. scibot 12 Feb 2022
  
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  DOI: 10.7554/eLife.73439
  
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elifesciences.org/articles/73439
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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

2
1. scibot 11 Feb 2022
  
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  CCL-247
  
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  CCL-247
  
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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

1
1. scibot 02 Feb 2022
  
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  ATCCCat#CCL-247
  
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Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers

1
1. scibot 02 Feb 2022
  
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  ATCCCat#CCL-247
  
  DOI: 10.1016/j.celrep.2022.110304
  
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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage

1
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  DOI: 10.1016/j.molcel.2022.01.001
  
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sciencedirect.com/science/article/pii/S1097276522000016
Jan 2022
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Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells

1
1. scibot 15 Jan 2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8752093/
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Feedback-regulated transcriptional repression of FBXO31 by c-Myc triggers ovarian cancer tumorigenesis

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  DOI: 10.1002/ijc.33854
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33854
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NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein

1
1. scibot 05 Jan 2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8666707/
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AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8254761/
Dec 2021
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Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

1
1. scibot 29 Dec 2021
  
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  CCL-247
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11166264/
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USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1

1
1. scibot 29 Dec 2021
  
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  CCL-247
  
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MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

1
1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.neo.2021.12.003
  
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sciencedirect.com/science/article/pii/S147655862100107X
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Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer

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1. scibot 16 Dec 2021
  
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  DOI: 10.1016/j.ebiom.2021.103750
  
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sciencedirect.com/science/article/pii/S2352396421005442
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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

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  DOI: 10.1016/j.molcel.2021.11.015
  
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sciencedirect.com/science/article/pii/S1097276521009953
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

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  DOI: 10.7554/eLife.62644
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

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  CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-20-3371
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

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  DOI: 10.1016/j.celrep.2021.110069
  
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Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I

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  DOI: 10.1016/j.chembiol.2021.11.002
  
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sciencedirect.com/science/article/pii/S2451945621004797
Nov 2021
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Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition

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1. scibot 30 Nov 2021
  
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  CCL-247
  
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

2
1. scibot 24 Nov 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.110056
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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  RRIDCUR:Missing RRID:CVCL_0291
2. scibot 24 Nov 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.110056
  
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sciencedirect.com/science/article/pii/S2211124721015424
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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
1. scibot 23 Nov 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.bioorg.2021.105505
  
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sciencedirect.com/science/article/pii/S004520682100883X
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 19 Nov 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1111/febs.16261
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.16261
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Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation

1
1. scibot 19 Nov 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.molcel.2021.11.003
  
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sciencedirect.com/science/article/pii/S1097276521009539
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Short-chain fatty acids activate acetyltransferase p300

1
1. scibot 19 Nov 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.72171
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8585482/
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Toward comprehensive imaging of oncolytic viroimmunotherapy

1
1. scibot 18 Nov 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.omto.2021.06.010
  
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sciencedirect.com/science/article/pii/S2372770521000905
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Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity

1
1. scibot 18 Nov 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2021.103323
  
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sciencedirect.com/science/article/pii/S258900422101292X
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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
1. scibot 12 Nov 2021
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2021.10.015
  
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sciencedirect.com/science/article/pii/S1097276521009072
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Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

1
1. scibot 10 Nov 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109989
  
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sciencedirect.com/science/article/pii/S2211124721014686
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
1. scibot 05 Nov 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ebiom.2021.103646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
Oct 2021
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Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

1
1. scibot 29 Oct 2021
  
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  RRID: CVCL_0291
  
  DOI: 10.1016/j.chembiol.2021.10.007
  
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sciencedirect.com/science/article/pii/S2451945621004414
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator

1
1. scibot 29 Oct 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2021.10.003
  
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sciencedirect.com/science/article/pii/S2451945621004372
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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

1
1. scibot 27 Oct 2021
  
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  CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.109899
  
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sciencedirect.com/science/article/pii/S2211124721013693
www.nature.com www.nature.com

XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer

1
1. scibot 23 Oct 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41392-021-00761-7
  
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nature.com/articles/s41392-021-00761-7
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USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork

1
1. scibot 13 Oct 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109819
  
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sciencedirect.com/science/article/pii/S2211124721012833
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Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

1
1. scibot 13 Oct 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.109815
  
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sciencedirect.com/science/article/pii/S2211124721012791
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Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments

1
1. scibot 12 Oct 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.envint.2021.106921
  
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sciencedirect.com/science/article/pii/S0160412021005468
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Proteome-wide mapping of short-lived proteins in human cells

1
1. scibot 09 Oct 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2021.09.015
  
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sciencedirect.com/science/article/pii/S1097276521007498
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines

1
1. scibot 06 Oct 2021
  
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  CVCL_0291
  
  DOI: 10.1038/s41598-021-98869-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
academic.oup.com academic.oup.com

Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions

1
1. scibot 01 Oct 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1210/clinem/dgab651
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
Sep 2021
www.mdpi.com www.mdpi.com

Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates

1
1. scibot 29 Sep 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.3390/ph14100950
  
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mdpi.com/1424-8247/14/10/950
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Oncogene-dependent sloppiness in mRNA translation

1
1. scibot 25 Sep 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2021.09.002
  
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sciencedirect.com/science/article/pii/S109727652100736X
academic.oup.com academic.oup.com

CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase

1
1. scibot 24 Sep 2021
  
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  CCL-247
  
  DOI: 10.1093/nar/gkab805
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
onlinelibrary.wiley.com onlinelibrary.wiley.com

Alternative microexon splicing by RBFOX2 and PTBP1 is associated with metastasis in colorectal cancer

1
1. scibot 23 Sep 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.33758
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33758
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ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

1
1. scibot 22 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109706
  
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sciencedirect.com/science/article/pii/S2211124721011530
onlinelibrary.wiley.com onlinelibrary.wiley.com

Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

1
1. scibot 22 Sep 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/cam4.4212
  
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onlinelibrary.wiley.com/doi/10.1002/cam4.4212
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Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer

1
1. scibot 21 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.lfs.2021.119949
  
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sciencedirect.com/science/article/pii/S002432052100936X
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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

1
1. scibot 14 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.ccell.2021.08.009
  
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sciencedirect.com/science/article/pii/S1535610821004499
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REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

1
1. scibot 11 Sep 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2021.08.016
  
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sciencedirect.com/science/article/pii/S1097276521006833
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SPT5 stabilization of promoter-proximal RNA polymerase II

1
1. scibot 04 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2021.08.006
  
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sciencedirect.com/science/article/pii/S1097276521006468
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High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment

1
1. scibot 02 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109632
  
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sciencedirect.com/science/article/pii/S2211124721010755
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iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation

1
1. scibot 02 Sep 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109642
  
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sciencedirect.com/science/article/pii/S2211124721010858
Aug 2021
link.springer.com link.springer.com

YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

1
1. scibot 31 Aug 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1007/s13402-021-00630-z
  
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link.springer.com/article/10.1007/s13402-021-00630-z
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Entosis is induced by UV radiation.

1
1. scibot 16 Aug 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2021.102902
  
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sciencedirect.com/science/article/pii/S2589004221008701
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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

1
1. scibot 14 Aug 2021
  
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  RRID: CVCL_0291
  
  DOI: 10.3389/fcell.2021.660159
  
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  Curator: @evieth
  
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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

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KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses

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BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination

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Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

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Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.

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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

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FEBS Press

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination

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  HCT116
  
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

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  HCT116
  
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Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis

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NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor

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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

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Widespread and Functional RNA Circularization in Localized Prostate Cancer

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Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

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  HCT116
  
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

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The Cancer SENESCopedia: A delineation of cancer cell senescence

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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

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Oncogenic MYC amplifies mitotic perturbations

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Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells

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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

1
1. scibot 29 Jul 2021
  
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  Human: HCT116
  
  DOI: 10.1016/j.celrep.2019.07.050
  
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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
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Untitled document

1
1. scibot 29 Jul 2021
  
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Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

2
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.32692
  
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2. scibot 27 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.32692
  
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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

1
1. scibot 28 Jul 2021
  
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  HCT-116 colorectal cancer cell line, human
  
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Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

1
1. scibot 27 Jul 2021
  
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  CCL-247
  
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

1
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

1
1. scibot 27 Jul 2021
  
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  CCL-247
  
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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
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  CVCL_0291
  
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CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity

1
1. scibot 20 Jul 2021
  
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  CCL-247
  
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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

1
1. scibot 16 Jul 2021
  
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  CCL-247
  
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BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells

1
1. scibot 14 Jul 2021
  
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  CCL-247
  
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Protein disulfide isomerase inhibits endoplasmic reticulum stress response and apoptosis via its oxidoreductase activity in colorectal cancer

1
1. scibot 11 Jul 2021
  
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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

1
1. scibot 10 Jul 2021
  
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  CCL-247
  
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Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

1
1. scibot 09 Jul 2021
  
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  CCL-247
  
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sciencedirect.com/science/article/pii/S2211124721006872
Jun 2021
cancerres.aacrjournals.org cancerres.aacrjournals.org

STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

1
1. scibot 29 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-20-2874
  
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cancerres.aacrjournals.org/content/81/11/2943
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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

1
1. scibot 17 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.58342
  
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elifesciences.org/articles/58342
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
1. scibot 17 Jun 2021
  
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  RRID:CVCL_0291
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8192123/
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KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

1
1. scibot 17 Jun 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8195604/
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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

1
1. scibot 16 Jun 2021
  
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  CCL-247
  
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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

1
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  DOI: 10.3390/cancers13112840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

1
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  CCL-247
  
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TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

1
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  CCL-247
  
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Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis

1
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  DOI: 10.1016/j.canlet.2021.05.033
  
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May 2021
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Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

1
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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

1
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  DOI: 10.1002/ijc.33562
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33562
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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer

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onlinelibrary.wiley.com/doi/10.1002/ijc.33561
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Immuno-PET Molecular Imaging of RANKL in Cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8124205/
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Grade-targeted nanoparticles for improved hypoxic tumor microenvironment and enhanced photodynamic cancer therapy

1
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  DOI: 10.2217/nnm-2020-0096
  
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futuremedicine.com/doi/abs/10.2217/nnm-2020-0096
cancerres.aacrjournals.org cancerres.aacrjournals.org

Survivin Expression is Differentially Regulated by a Selective Crosstalk between Rbm38 and miRNAs let-7b or miR-203a

1
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BPS Publications

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Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

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POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

1
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Synergistic antitumor activity of DHA and JQ1 in colorectal carcinoma

1
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  DOI: 10.1016/j.ejphar.2020.173500
  
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FEBS Press

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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12953
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.cmet.2021.03.003
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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sciencedirect.com/science/article/pii/S1550413121001108
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

1
1. scibot 01 May 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.molcel.2021.04.009
  
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sciencedirect.com/science/article/pii/S1097276521003142
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The Source of Glycolytic Intermediates in Mammalian Tissues

1
1. scibot 01 May 2021
  
  in Public
  
  CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.020
  
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sciencedirect.com/science/article/pii/S1550413120307282
Apr 2021
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Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

1
1. scibot 30 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.002
  
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sciencedirect.com/science/article/pii/S1550413120306574
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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

1
1. scibot 29 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1007/s00018-021-03818-6
  
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link.springer.com/article/10.1007/s00018-021-03818-6
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Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

1
1. scibot 28 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108999
  
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sciencedirect.com/science/article/pii/S2211124721003132
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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

1
1. scibot 28 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2021.04.004
  
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sciencedirect.com/science/article/pii/S2451945621001598
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Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

2
1. scibot 28 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
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2. scibot 08 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
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Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

1
1. scibot 27 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2020.07.017
  
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sciencedirect.com/science/article/pii/S2451945620302907
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Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

1
1. scibot 24 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cell.2020.07.030
  
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sciencedirect.com/science/article/pii/S0092867420309387
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cell.2020.07.009
  
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sciencedirect.com/science/article/pii/S0092867420308746
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Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells

1
1. scibot 24 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cell.2020.06.037
  
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sciencedirect.com/science/article/pii/S009286742030814X
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MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

1
1. scibot 22 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2020.11.004
  
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sciencedirect.com/science/article/pii/S1535610820305961
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Integrated Omics of Metastatic Colorectal Cancer

1
1. scibot 22 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2020.08.002
  
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sciencedirect.com/science/article/pii/S153561082030413X
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High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

1
1. scibot 21 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109026
  
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sciencedirect.com/science/article/pii/S2211124721003405
www.tandfonline.com www.tandfonline.com

The Targeting Effect of Cetuximab Combined with PD-L1 Blockade against EGFR-Expressing Tumors in a Tailored CD16-CAR T-Cell Reporter System

1
1. scibot 19 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1080/07357907.2021.1894570
  
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tandfonline.com/doi/full/10.1080/07357907.2021.1894570
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Efferocytosis by Paneth cells within the intestine

1
1. scibot 14 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cub.2021.03.055
  
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sciencedirect.com/science/article/pii/S0960982221004280
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

1
1. scibot 12 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ceca.2021.102384
  
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sciencedirect.com/science/article/pii/S0143416021000385
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Creatine promotes cancer metastasis through activation of Smad2/3

1
1. scibot 06 Apr 2021
  
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  Cat#CCL-247
  
  DOI: 10.1016/j.cmet.2021.03.009
  
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sciencedirect.com/science/article/pii/S1550413121001169
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SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation

1
1. scibot 01 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108921
  
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sciencedirect.com/science/article/pii/S2211124721002357
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PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

1
1. scibot 01 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.108928
  
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sciencedirect.com/science/article/pii/S2211124721002424
Mar 2021
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SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells

1
1. scibot 18 Mar 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108821
  
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sciencedirect.com/science/article/pii/S2211124721001352
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis

1
1. scibot 17 Mar 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.3389/fcell.2021.629893
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7959841/
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Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks

1
1. scibot 10 Mar 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.3389/fgene.2021.613808
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7937961/
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A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

1
1. scibot 04 Mar 2021
  
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  HCT116
  
  DOI: 10.1016/j.chembiol.2021.02.006
  
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sciencedirect.com/science/article/pii/S2451945621000581
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

1
1. scibot 02 Mar 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41598-021-83979-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7904805/
Feb 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 28 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1111/bph.15350
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15350
cancerres.aacrjournals.org cancerres.aacrjournals.org

3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer

1
1. scibot 28 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-20-1822
  
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cancerres.aacrjournals.org/content/81/4/847
link.springer.com link.springer.com

Bacteria‐derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis‐associated cancer

1
1. scibot 27 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1186/s12935-020-01723-9
  
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link.springer.com/article/10.1186/s12935-020-01723-9
bmccancer.biomedcentral.com bmccancer.biomedcentral.com

Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer

1
1. scibot 26 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1186/s12885-021-07900-x
  
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bmccancer.biomedcentral.com/article/10.1186/s12885-021-07900-x
elifesciences.org elifesciences.org

p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways

1
1. scibot 25 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.31723
  
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elifesciences.org/articles/31723
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An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

1
1. scibot 24 Feb 2021
  
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  HCT116
  
  DOI: 10.1016/j.celrep.2021.108744
  
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sciencedirect.com/science/article/pii/S2211124721000577
onlinelibrary.wiley.com onlinelibrary.wiley.com

Regulation of immune cell metabolism by cancer cell oncogenic mutations

1
1. scibot 24 Feb 2021
  
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  CVCL_0291
  
  DOI: 10.1002/ijc.32888
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32888
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Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy

1
1. scibot 24 Feb 2021
  
  in Public
  
  CVCL_0291
  
  DOI: 10.1016/j.biopha.2019.109648
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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sciencedirect.com/science/article/pii/S0753332219352709
onlinelibrary.wiley.com onlinelibrary.wiley.com

Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single‐Cell Analysis of Transcriptome and Telomeres

1
1. scibot 24 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/advs.202004320
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202004320
elifesciences.org elifesciences.org

The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure

1
1. scibot 24 Feb 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.61797
  
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elifesciences.org/articles/61797
Jan 2021
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Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer

1
1. scibot 27 Jan 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2020.108676
  
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sciencedirect.com/science/article/pii/S221112472031665X
www.nature.com www.nature.com

Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells

1
1. scibot 26 Jan 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41596-020-00454-5
  
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nature.com/articles/s41596-020-00454-5
www.sciencedirect.com www.sciencedirect.com

Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes

1
1. scibot 21 Jan 2021
  
  in Public
  
  HCT116
  
  DOI: 10.1016/j.xpro.2020.100277
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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sciencedirect.com/science/article/pii/S2666166720302641
www.sciencedirect.com www.sciencedirect.com

Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation

1
1. scibot 20 Jan 2021
  
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  HCT116
  
  DOI: 10.1016/j.celrep.2020.108635
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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sciencedirect.com/science/article/pii/S2211124720316247
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Prolonged mitosis causes separase deregulation and chromosome nondisjunction

1
1. scibot 20 Jan 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2020.108652
  
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sciencedirect.com/science/article/pii/S2211124720316417
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Polyphenolic Fraction Obtained From Thalassia testudinum Marine Plant and Thalassiolin B Exert Cytotoxic Effects in Colorectal Cancer Cells and Arrest Tumor Progression in a Xenograft Mouse Model

1
1. scibot 07 Jan 2021
  
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  RRID:CVCL-0291
  
  DOI: 10.3389/fphar.2020.592985
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7774314/
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Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1

1
1. scibot 06 Jan 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.63614
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7773337/
Dec 2020
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Cetuximab enhances the anti-tumor function of macrophages in an IL-6 dependent manner

1
1. scibot 31 Dec 2020
  
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  RRID: CVCL_0291
  
  DOI: 10.1016/j.lfs.2020.118953
  
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sciencedirect.com/science/article/pii/S0024320520317136
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.2147/OTT.S278582
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7695693/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Gracillin shows potent efficacy against colorectal cancer through inhibiting the STAT3 pathway

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1111/jcmm.16134
  
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onlinelibrary.wiley.com/doi/full/10.1111/jcmm.16134
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TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2020.108418
  
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sciencedirect.com/science/article/pii/S2211124720314078
www.embopress.org www.embopress.org

Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA

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1. scibot 07 Dec 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.15252/embj.2019103654
  
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embopress.org/doi/abs/10.15252/embj.2019103654
Nov 2020
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 10 Nov 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/1878-0261.12821
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12821
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth

1
1. scibot 07 Nov 2020
  
  in Public
  
  HCT116
  
  DOI: 10.1016/j.celrep.2020.108332
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
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pubmed.ncbi.nlm.nih.gov/33147457/
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PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage

1
1. scibot 07 Nov 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2020.108347
  
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sciencedirect.com/science/article/pii/S221112472031336X
cancerci.biomedcentral.com cancerci.biomedcentral.com

Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity

1
1. scibot 04 Nov 2020
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1186/s12935-020-01598-w
  
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cancerci.biomedcentral.com/article/10.1186/s12935-020-01598-w
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory

1
1. scibot 03 Nov 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2020.10.005
  
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pubmed.ncbi.nlm.nih.gov/33108759/
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Vitamin D as a Primer for Oncolytic Viral Therapy in Colon Cancer Models

1
1. scibot 31 Oct 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.3390/ijms21197326
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7582493/
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The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression

1
1. scibot 29 Oct 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41419-020-03095-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7584667/
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Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

1
1. scibot 08 Oct 2020
  
  in Public
  
  HCT116
  
  DOI: 10.1016/j.celrep.2020.108231
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
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pubmed.ncbi.nlm.nih.gov/33027658/

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