1,108 Matching Annotations
  1. Nov 2021
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124721015424
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    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    sciencedirect.com/science/article/pii/S004520682100883X
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16261
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    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
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    sciencedirect.com/science/article/pii/S1097276521009539
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    Short-chain fatty acids activate acetyltransferase p300
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    ncbi.nlm.nih.gov/pmc/articles/PMC8585482/
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    Toward comprehensive imaging of oncolytic viroimmunotherapy
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    sciencedirect.com/science/article/pii/S2372770521000905
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    Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity
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    sciencedirect.com/science/article/pii/S258900422101292X
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    sciencedirect.com/science/article/pii/S1097276521009072
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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    sciencedirect.com/science/article/pii/S2211124721014686
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    Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
  12. Oct 2021
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    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
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    sciencedirect.com/science/article/pii/S2451945621004414
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    Reprogramming CBX8-PRC1 function with a positive allosteric modulator
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    sciencedirect.com/science/article/pii/S2451945621004372
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    sciencedirect.com/science/article/pii/S2211124721013693
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    XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer
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    nature.com/articles/s41392-021-00761-7
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    USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork
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    sciencedirect.com/science/article/pii/S2211124721012833
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    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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    sciencedirect.com/science/article/pii/S2211124721012791
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    Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments
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    sciencedirect.com/science/article/pii/S0160412021005468
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    Proteome-wide mapping of short-lived proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276521007498
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    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
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    Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
  23. Sep 2021
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    Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates
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    mdpi.com/1424-8247/14/10/950
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    Oncogene-dependent sloppiness in mRNA translation
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    CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
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    Alternative microexon splicing by RBFOX2 and PTBP1 is associated with metastasis in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33758
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    ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction
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    Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/cam4.4212
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    Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer
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    Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
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    SPT5 stabilization of promoter-proximal RNA polymerase II
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    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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    sciencedirect.com/science/article/pii/S2211124721010755
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    iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation
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  36. Aug 2021
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    YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models
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    link.springer.com/article/10.1007/s13402-021-00630-z
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    Entosis is induced by UV radiation.
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    sciencedirect.com/science/article/pii/S2589004221008701
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    Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8355564/
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    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
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    biorxiv.org/content/10.1101/141952v4
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    ncbi.nlm.nih.gov/pmc/articles/PMC5836092/
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    elifesciences.org/articles/26876
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27653
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    KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses
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    sciencedirect.com/science/article/pii/S1931312818301483
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    BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
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    nature.com/articles/s41586-021-03776-w
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
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    ncbi.nlm.nih.gov/pmc/articles/PMC8331188/
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    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
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    sciencedirect.com/science/article/pii/S1534580721005621
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    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.
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    europepmc.org/articles/PMC5655136/
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    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
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    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12600
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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    sciencedirect.com/science/article/pii/S1097276519307944
  62. Jul 2021
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    Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    sciencedirect.com/science/article/pii/S2211124719314056
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    Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis
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    sciencedirect.com/science/article/pii/S1097276519307932
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    NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor
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    sciencedirect.com/science/article/pii/S2211124719312914
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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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    Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone
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    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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    The Cancer SENESCopedia: A delineation of cancer cell senescence
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    Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization
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    sciencedirect.com/science/article/pii/S2352396419307522
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    Oncogenic MYC amplifies mitotic perturbations
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    royalsocietypublishing.org/doi/full/10.1098/rsob.190136
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    Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells
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    onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32608
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    Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
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    Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy
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    elifesciences.org/articles/27301
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    Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair
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    The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation
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    Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion
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    sciencedirect.com/science/article/pii/S0960982218313356
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    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
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    Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC5605498/
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    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
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    CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
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    Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
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    BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
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    Protein disulfide isomerase inhibits endoplasmic reticulum stress response and apoptosis via its oxidoreductase activity in colorectal cancer
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    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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    sciencedirect.com/science/article/pii/S0960982221008253
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    Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells
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  92. Jun 2021
  93. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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    cancerres.aacrjournals.org/content/81/11/2943
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    Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis
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    Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8192123/
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    KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8195604/
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    Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling
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