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Sep 2020
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Single-Cell Transcriptome Analysis of Colon Cancer Cell Response to 5-Fluorouracil-Induced DNA Damage

1
1. scibot 03 Sep 2020
  
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  HCT116
  
  DOI: 10.1016/j.celrep.2020.108077
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720310627
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Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay

1
1. scibot 03 Sep 2020
  
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  HCT116
  
  DOI: 10.1016/j.celrep.2020.107895
  
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sciencedirect.com/science/article/pii/S2211124720308767
www.cell.com www.cell.com

Structure of the Inhibited State of the Sec Translocon

1
1. scibot 03 Sep 2020
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2020.06.013
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30398-1
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance

1
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32845
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32845
elifesciences.org elifesciences.org

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

1
1. scibot 03 Sep 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.44525
  
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elifesciences.org/articles/44525
Aug 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Integrin-Linked-Kinase Overexpression Is Implicated in Mechanisms of Genomic Instability in Human Colorectal Cancer

1
1. scibot 31 Aug 2020
  
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  HCT116
  
  DOI: 10.1007/s10620-020-06364-6
  
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pubmed.ncbi.nlm.nih.gov/32495257/
cancerres.aacrjournals.org cancerres.aacrjournals.org

CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer

1
1. scibot 14 Aug 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-19-1161
  
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cancerres.aacrjournals.org/content/80/2/334
Jan 2020
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Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2019.08.003
  
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sciencedirect.com/science/article/pii/S2451945619302491
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Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2019.11.010
  
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sciencedirect.com/science/article/pii/S2451945619303927
elifesciences.org elifesciences.org

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.45068
  
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elifesciences.org/articles/45068
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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2019.09.018
  
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sciencedirect.com/science/article/pii/S1097276519307233
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N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_0291
  
  DOI: 10.3390/cancers11101456
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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mdpi.com/2072-6694/11/10/1456
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Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

1
1. scibot 13 Jan 2020
  
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  CVCL_0291
  
  DOI: 10.1016/j.celrep.2019.08.051
  
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sciencedirect.com/science/article/pii/S221112471931099X
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Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cmet.2019.09.009
  
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sciencedirect.com/science/article/pii/S1550413119305121
onlinelibrary.wiley.com onlinelibrary.wiley.com

A Chirality‐Dependent Action of Vitamin C in Suppressing KRAS Mutant Tumor Growth by the Oxidative Combination: Rationale for Cancer Therapeutics

1
1. scibot 13 Jan 2020
  
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  CVCL_0291
  
  DOI: 10.1002/ijc.32658
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32658
onlinelibrary.wiley.com onlinelibrary.wiley.com

CD16‐158‐Valine Chimeric Receptor T Cells Overcome the Resistance of Kras‐Mutated Colorectal Carcinoma Cells to Cetuximab

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32618
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32618
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Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2019.09.079
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @ethanbadger
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719312835
onlinelibrary.wiley.com onlinelibrary.wiley.com

Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32709
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32709
onlinelibrary.wiley.com onlinelibrary.wiley.com

ANKLE1 N6‐Methyladenosine‐related variant is associated with colorectal cancer risk by maintaining the genomic stability

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32677
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32677
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VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cels.2019.05.009
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2405471219301905
elifesciences.org elifesciences.org

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.48625
  
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elifesciences.org/articles/48625
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γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2019.09.007
  
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sciencedirect.com/science/article/pii/S1097276519306926
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2018.09.008
  
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  Curator: @evieth
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6309520/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32670
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32670
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Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2019.06.005
  
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sciencedirect.com/science/article/pii/S2451945619302065
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mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2017.09.013
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817304178
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1111/bph.14770
  
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14770
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Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

1
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.devcel.2019.07.010
  
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  RRID:CVCL_0291 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580719305829
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0291
  
  DOI: 10.1111/bph.14863
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14863
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Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

1
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cub.2019.01.029
  
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sciencedirect.com/science/article/pii/S0960982219300314
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Untitled document

1
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2019.04.006
  
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sciencedirect.com/science/article/pii/S1535610819302016
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Untitled document

1
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.stem.2019.04.005
  
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sciencedirect.com/science/article/pii/S1934590919301547
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Untitled document

1
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2019.02.052
  
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sciencedirect.com/science/article/pii/S2211124719302311
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Untitled document

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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2018.11.013
  
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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

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FXR Regulates Intestinal Cancer Stem Cell Proliferation

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TP53 drives invasion through expression of its Δ133p53β variant

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Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

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Histone-lysine N-methyltransferase SETD7 is a potential serum biomarker for colorectal cancer patients

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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

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A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival

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The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor

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Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals

1
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Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila

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Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

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Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11

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Systematic Characterization of Stress-Induced RNA Granulation

1
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Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers

1
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AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

1
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Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis

1
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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

1
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A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency

1
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  ATCC CCL-247
  
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USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms

1
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iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding

1
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GPR68 Senses Flow and Is Essential for Vascular Physiology

1
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A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity

1
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PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

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Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells

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onlinelibrary.wiley.com/doi/10.15252/embr.201745336/full
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mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

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A Method for the Acute and Rapid Degradation of Endogenous Proteins

2
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0291
  
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Untitled document

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europepmc.org/articles/PMC5745086/
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A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth

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Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer

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Untitled document

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Untitled document

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Nov 2017
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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

1
1. scibot 08 Nov 2017
  
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  CCL-247
  
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The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence

1
1. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5602299/
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A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product

1
1. scibot 08 Nov 2017
  
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  CCL-247
  
  Curator: @Jmenke
  
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elifesciences.org elifesciences.org

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

1
1. scibot 08 Nov 2017
  
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  CVCL_0291
  
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elifesciences.org/articles/27713
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PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex

1
1. scibot 08 Nov 2017
  
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elifesciences.org/articles/24578
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Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

1
1. scibot 08 Nov 2017
  
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  CCL-247
  
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Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling

1
1. scibot 08 Nov 2017
  
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  CCL-247
  
  Curator: @Jmenke
  
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Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

1
1. scibot 08 Nov 2017
  
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  ATCC-CCL-247
  
  Curator: @Jmenke
  
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Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses

1
1. scibot 08 Nov 2017
  
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  HCT116ATCCCat#CCL-247
  
  Curator: @Jmenke
  
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BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

1
1. scibot 08 Nov 2017
  
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  HCT116ATCCCat#CCL-247
  
  Curator: @Jmenke
  
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Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

1
1. scibot 08 Nov 2017
  
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  HCT116ATCCCat#CCL-247
  
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MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect

1
1. scibot 08 Nov 2017
  
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elifesciences.org/articles/22477
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Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining

1
1. scibot 08 Nov 2017
  
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  CVCL_0291
  
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RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice

1
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CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

1
1. scibot 08 Nov 2017
  
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  HCT116
  
  Curator: @kaitlinsung
  
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Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a

1
1. scibot 08 Nov 2017
  
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  CVCL_0291
  
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Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation

1
1. scibot 08 Nov 2017
  
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  uman: HCT116
  
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ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation

1
1. scibot 08 Nov 2017
  
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  Cat# CCL-247
  
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Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion

1
1. scibot 08 Nov 2017
  
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  CCL-247
  
  Curator: @Zeljana_Babic
  
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Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

1
1. scibot 08 Nov 2017
  
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  CVCL_0291
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5127641/
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Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation

1
1. scibot 08 Nov 2017
  
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  CVCL_0291
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4959878/

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