897 Matching Annotations
  1. Sep 2020
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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    sciencedirect.com/science/article/pii/S153561081930577X
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    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches
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    cancerres.aacrjournals.org/content/80/7/1475
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    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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    sciencedirect.com/science/article/pii/S0092867420302701
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    Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7200154/
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    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
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    sciencedirect.com/science/article/pii/S1097276519309529
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    Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
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    sciencedirect.com/science/article/pii/S2211124720310524
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    Axon-like protrusions promote small cell lung cancer migration and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6940020/
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    Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia
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    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
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    Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis
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    Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
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    Rapid generation of Col7a1 −/− mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells
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    Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling
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    The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer
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    Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice
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    nature.com/articles/s41598-019-55729-z
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    Isolation of satellite cells and transplantation into mice for lineage tracing in muscle
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    nature.com/articles/s41596-019-0278-8
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    Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
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    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
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    MYC Controls the Epstein-Barr Virus Lytic Switch
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    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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    Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
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    Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures
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    Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity
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    Protocol for Cloning Epithelial Stem Cell Variants from Human Lung
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  28. Aug 2020
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    Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    Exosome/Microvesicle Content is Altered in LRRK2 Mutant iPSC‐derived Neural Cells
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    onlinelibrary.wiley.com/doi/10.1002/cne.24819
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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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  33. Jan 2020
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    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
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  35. cancerres.aacrjournals.org cancerres.aacrjournals.org
    HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
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    cancerres.aacrjournals.org/content/78/21/6196
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    CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies
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    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
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    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
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  50. Nov 2018
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    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
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    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
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    sciencedirect.com/science/article/pii/S0896627318308481
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1550413118306284
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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
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    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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    Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC6134179/
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    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
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    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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    cell.com/cell-stem-cell/fulltext/S1934-5909(18)30284-4
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    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
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    Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus
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    An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
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    The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
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    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
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    Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC6643283/
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase
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    TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.
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  77. Nov 2017
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    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling
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    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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    Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia
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    Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1
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    Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
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    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
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    Stable and Potent Selenomab-Drug Conjugates
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    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
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    Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
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    Prevention of intestinal ischemia-reperfusion injury in humanized mice
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    Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression
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    A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis
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    Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
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