2,250 Matching Annotations
  1. Feb 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy
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    1. scibot 08 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827061/
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    Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827163/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10840244/
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    1. scibot 08 Feb 2024
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    nature.com/articles/s41467-024-45067-8
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
    1
    1. scibot 08 Feb 2024
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  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1186/s12885-024-11895-6

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    Effect of Octamer-Binding Transcription Factor 4 Overexpression on the Neural Induction of Human Dental Pulp Stem Cells
    1
    1. scibot 07 Feb 2024
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    One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics
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    1. scibot 07 Feb 2024
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    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
    1
    1. scibot 06 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000091
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    The cyclimids: Degron-inspired cereblon binders for targeted protein degradation
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    1. scibot 06 Feb 2024
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    sciencedirect.com/science/article/pii/S2451945624000394
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    1. scibot 06 Feb 2024
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      DOI: 10.1158/2326-6066.CIR-23-0211

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    aacrjournals.org/cancerimmunolres/article/12/2/232/733764/Single-Cell-Transcriptomics-Reveals-the
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    Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid
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    1. scibot 06 Feb 2024
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  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immortalization of American miniature horse-derived fibroblast by cell cycle regulator with normal karyotype
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    1. scibot 06 Feb 2024
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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computational prediction and experimental validation identify functionally conserved lncRNAs from zebrafish to human
    1
    1. scibot 05 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10786727/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleolar protein TAAP1/C22orf46 confers pro-survival signaling in non-small cell lung cancer
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    1. scibot 05 Feb 2024
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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive Endolysosomal Perforation in Neurons allows Induction of α-Synuclein Aggregation by Internalized Pre-Formed Fibrils
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    1. scibot 05 Feb 2024
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis and validation reveal CYTH4 as a potential prognostic biomarker in acute myeloid leukemia
    1
    1. scibot 05 Feb 2024
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      DOI: 10.3892/ol.2024.14236

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATP7A-dependent copper sequestration contributes to termination of β-CATENIN signaling during early adipogenesis
    1
    1. scibot 05 Feb 2024
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NPAS2 dampens chemo-sensitivity of lung adenocarcinoma cells by enhancing DNA damage repair
    1
    1. scibot 05 Feb 2024
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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBV promotes its replication by up-regulating RAD51C gene expression
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    1. scibot 05 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831117/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO38 deficiency promotes lysosome-dependent STING degradation and inhibits cGAS–STING pathway activation
    1
    1. scibot 05 Feb 2024
      psPAX2

      DOI: 10.1016/j.neo.2024.100973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10832482/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
    1. scibot 05 Feb 2024
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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
    1
    1. scibot 05 Feb 2024
      plasmid_12260

      DOI: 10.21203/rs.3.rs-3640969/v1

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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression
    1
    1. scibot 05 Feb 2024
      plasmid_12260

      DOI: 10.1101/2024.01.02.573986

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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discoveries of GPR39 as an evolutionarily conserved receptor for bile acids and of its involvement in biliary acute pancreatitis
    1
    1. scibot 04 Feb 2024
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      DOI: 10.1126/sciadv.adj0146

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    ncbi.nlm.nih.gov/pmc/articles/PMC10836733/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch3 directs differentiation of brain mural cells from human pluripotent stem cell–derived neural crest
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing of latrophilin-3 controls synapse formation
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    1. scibot 04 Feb 2024
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma
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      DOI: 10.1038/s41467-024-45128-y

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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 Capsid Uncoating Is a Multistep Process That Proceeds through Defect Formation Followed by Disassembly of the Capsid Lattice
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  35. www.biorxiv.org www.biorxiv.org
    Tim-1 and Tim-4 mediate entry of the human Kaposi’s sarcoma-associated herpesvirus and the related rhesus monkey rhadinovirus
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      plasmid_12260

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  37. www.sciencedirect.com www.sciencedirect.com
    3D bioprinting of human neural tissues with functional connectivity
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  38. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
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  39. www.sciencedirect.com www.sciencedirect.com
    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulations in the host cell proteome by the hantavirus nucleocapsid protein
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OPN promotes pro-inflammatory cytokine expression via ERK/JNK pathway and M1 macrophage polarization in Rosacea
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    ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells
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      DOI: 10.1002/1878-0261.13589

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13589
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling
    1
    1. scibot 01 Feb 2024
      Addgene_12260

      DOI: 10.1101/2024.01.04.574136

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802300/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Charting Single Cell Lineage Dynamics and Mutation Networks via Homing CRISPR
    1
    1. scibot 01 Feb 2024
      Addgene_12260

      DOI: 10.1101/2024.01.05.574236

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802354/
  47. Jan 2024
  48. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells
    1
    1. scibot 31 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1002/1878-0261.13589

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13589
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells
    1
    1. scibot 30 Jan 2024
      12260

      DOI: 10.1038/s41467-024-44885-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798966/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircNUP50 is a novel therapeutic target that promotes cisplatin resistance in ovarian cancer by modulating p53 ubiquitination
    1
    1. scibot 30 Jan 2024
      GandpsPAX2

      DOI: 10.1186/s12951-024-02295-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10799427/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL
    1
    1. scibot 30 Jan 2024
      plasmid #12260

      DOI: 10.1038/s41419-024-06447-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10799905/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chimeric antigen-receptor (CAR) engineered natural killer cells in a chronic myeloid leukemia (CML) blast crisis model
    1
    1. scibot 30 Jan 2024
      ps-PAX2.2

      DOI: 10.3389/fimmu.2023.1309010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801069/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
    1
    1. scibot 30 Jan 2024
      AddGene 12260

      DOI: 10.1186/s13075-023-03259-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801937/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression
    1
    1. scibot 30 Jan 2024
      #12260, Addgene

      DOI: 10.1038/s41398-024-02744-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803733/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state
    1
    1. scibot 30 Jan 2024
      psPAX2

      DOI: 10.1038/s41419-024-06460-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10810848/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vutiglabridin Alleviates Cellular Senescence with Metabolic Regulation and Circadian Clock in Human Dermal Fibroblasts
    1
    1. scibot 30 Jan 2024
      psPAX2

      DOI: 10.3390/antiox13010109

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    ncbi.nlm.nih.gov/pmc/articles/PMC10812742/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset
    1
    1. scibot 30 Jan 2024
      Addgene, Watertown, MA, #12260

      DOI: 10.1038/s41467-024-45097-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10821902/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel mechanism of drug resistance triggered by tumor-associated macrophages through Heat Shock Factor-1 activation
    1
    1. scibot 30 Jan 2024
      psPAX

      DOI: 10.1007/s00262-023-03612-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10821977/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
    1
    1. scibot 30 Jan 2024
      Addgene_12260

      DOI: 10.1038/s41467-024-44958-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10799903/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LDLR is used as a cell entry receptor by multiple alphaviruses
    1
    1. scibot 30 Jan 2024
      plasmid_12260

      DOI: 10.1038/s41467-024-44872-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10799924/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing the secretome of EGFR mutant lung adenocarcinoma
    1
    1. scibot 30 Jan 2024
      Plasmid_12260

      DOI: 10.3389/fonc.2023.1286821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801028/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control
    1
    1. scibot 30 Jan 2024
      plasmid_12260

      DOI: 10.1038/s41419-024-06423-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803372/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95
    1
    1. scibot 30 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1101/2024.01.12.574705

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802569/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability
    1
    1. scibot 29 Jan 2024
      #12260; Addgene

      DOI: 10.3390/cells13020199

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    ncbi.nlm.nih.gov/pmc/articles/PMC10814814/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation
    1
    1. scibot 29 Jan 2024
      Addgene, Watertown, MA, USA, catalog 12260

      DOI: 10.3390/v16010116

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    ncbi.nlm.nih.gov/pmc/articles/PMC10819576/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles
    1
    1. scibot 29 Jan 2024
      plasmid_12260

      DOI: 10.1016/j.bioactmat.2023.12.027

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    ncbi.nlm.nih.gov/pmc/articles/PMC10821609/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway
    1
    1. scibot 29 Jan 2024
      Addgene_12260

      DOI: 10.3390/v16010113

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    ncbi.nlm.nih.gov/pmc/articles/PMC10819893/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia
    1
    1. scibot 29 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1007/s00018-023-05095-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10817852/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability
    1
    1. scibot 29 Jan 2024
      Plasmid_12260

      DOI: 10.1101/2024.01.12.575420

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802603/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition
    1
    1. scibot 28 Jan 2024
      psPAX2 plasmid (Addgene)

      DOI: 10.1128/jvi.00849-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10804985/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA
    1
    1. scibot 28 Jan 2024
      PsPAX2

      DOI: 10.1128/jvi.01350-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10805074/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids
    1
    1. scibot 28 Jan 2024
      psPAX2

      DOI: 10.3389/fcell.2023.1268226

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    ncbi.nlm.nih.gov/pmc/articles/PMC10806012/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier physiology in Friedreich’s ataxia
    1
    1. scibot 28 Jan 2024
      12,260

      DOI: 10.3389/fmolb.2023.1299201

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    ncbi.nlm.nih.gov/pmc/articles/PMC10808331/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Anti-CD47 Nanobody Tetramer for Cancer Therapy
    1
    1. scibot 28 Jan 2024
      plasmid_12260

      DOI: 10.3390/antib13010002

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801496/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abscisic acid signaling through LANCL2 and PPARγ induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells
    1
    1. scibot 28 Jan 2024
      plasmid_12260

      DOI: 10.3892/or.2024.8698

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    ncbi.nlm.nih.gov/pmc/articles/PMC10804438/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth
    1
    1. scibot 26 Jan 2024
      plasmid_12260

      DOI: 10.1016/j.jbc.2023.104713

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    ncbi.nlm.nih.gov/pmc/articles/PMC10200990/
  77. www.nature.com www.nature.com
    Cell-type-directed design of synthetic enhancers
    1
    1. scibot 25 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1038/s41586-023-06936-2

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    nature.com/articles/s41586-023-06936-2
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
    1
    1. scibot 20 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1128/mbio.02444-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10790771/
  79. www.sciencedirect.com www.sciencedirect.com
    Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma
    1
    1. scibot 19 Jan 2024
      Plasmid_12260

      DOI: 10.1016/j.celrep.2024.113678

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    sciencedirect.com/science/article/pii/S2211124724000068
  80. www.sciencedirect.com www.sciencedirect.com
    SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13
    1
    1. scibot 19 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1016/j.cellsig.2024.111060

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    sciencedirect.com/science/article/pii/S0898656824000287
  81. www.sciencedirect.com www.sciencedirect.com
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
    1
    1. scibot 19 Jan 2024
      RRID:Addgene_12

      DOI: 10.1016/j.canlet.2024.216635

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    sciencedirect.com/science/article/pii/S0304383524000296
  82. link.springer.com link.springer.com
    Generation and optimization of off-the-shelf immunotherapeutics targeting TCR-Vβ2+ T cell malignancy
    1
    1. scibot 18 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1038/s41467-024-44786-2

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    link.springer.com/article/10.1038/s41467-024-44786-2
  83. www.sciencedirect.com www.sciencedirect.com
    TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet
    1
    1. scibot 18 Jan 2024
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2024.113673

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    sciencedirect.com/science/article/pii/S2211124724000019
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment
    1
    1. scibot 13 Jan 2024
      Addgene_12260

      DOI: 10.1016/j.ccell.2023.12.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10783802/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
    1
    1. scibot 12 Jan 2024
      Addgene_12260

      DOI: 10.1042/BSR20231418

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance
    1
    1. scibot 12 Jan 2024
      plasmid_12260

      DOI: 10.1158/2767-9764.CRC-23-0298

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    ncbi.nlm.nih.gov/pmc/articles/PMC10702273/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct translation of incoming retroviral genomes
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  88. www.sciencedirect.com www.sciencedirect.com
    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
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  89. www.sciencedirect.com www.sciencedirect.com
    Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
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  90. 52.53.155.43 52.53.155.43
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  91. www.sciencedirect.com www.sciencedirect.com
    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
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    Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus
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  93. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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  94. www.sciencedirect.com www.sciencedirect.com
    Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct effects of adipocyte lipolysis on AMPK through intracellular long-chain acyl-CoA signaling
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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  98. Dec 2023
  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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  100. www.mdpi.com www.mdpi.com
    Comparative Analysis of Cyclization Techniques in Stapled Peptides: Structural Insights into Protein–Protein Interactions in a SARS-CoV-2 Spike RBD/hACE2 Model System
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  101. www.sciencedirect.com www.sciencedirect.com
    Human inherited CCR2 deficiency underlies progressive polycystic lung disease
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe
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  103. www.sciencedirect.com www.sciencedirect.com
    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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  104. www.sciencedirect.com www.sciencedirect.com
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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  105. www.sciencedirect.com www.sciencedirect.com
    High-throughput PRIME-editing screens identify functional DNA variants in the human genome
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  106. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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  108. www.sciencedirect.com www.sciencedirect.com
    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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  109. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
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    B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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  113. 52.53.155.43 52.53.155.43
    978-1-0716-3593-3-html.html
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  114. www.biorxiv.org www.biorxiv.org
    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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  116. journals.asm.org journals.asm.org
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes
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  119. www.sciencedirect.com www.sciencedirect.com
    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  120. www.sciencedirect.com www.sciencedirect.com
    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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  122. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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  123. www.nature.com www.nature.com
    Downstream STING pathways IRF3 and NF-κB differentially regulate CCL22 in response to cytosolic dsDNA
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  124. www.biorxiv.org www.biorxiv.org
    Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin
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  125. 52.53.155.43 52.53.155.43
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations
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  127. Nov 2023
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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  129. www.sciencedirect.com www.sciencedirect.com
    Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
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  130. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment
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    sciencedirect.com/science/article/pii/S2666379123004809
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    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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  133. www.sciencedirect.com www.sciencedirect.com
    Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
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    sciencedirect.com/science/article/pii/S1097276523009036
  134. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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  135. www.sciencedirect.com www.sciencedirect.com
    Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1
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  136. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells
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  138. www.biorxiv.org www.biorxiv.org
    Kaposi’s sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming by mutated IRF4 in lymphoma
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  140. www.sciencedirect.com www.sciencedirect.com
    Head and neck cancer stem cell maintenance relies on mTOR signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2)
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vimentin intermediate filaments provide structural stability to the mammalian Golgi complex
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro formation and extended culture of highly metabolically active and contractile tissues
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  147. www.sciencedirect.com www.sciencedirect.com
    Global identification of SWI/SNF targets reveals compensation by EP400
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  148. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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  150. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells
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    m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation
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  152. www.sciencedirect.com www.sciencedirect.com
    Efficient exon skipping by base-editor-mediated abrogation of exonic splicing enhancers
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  153. Oct 2023
  154. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling
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  156. www.sciencedirect.com www.sciencedirect.com
    Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells
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  157. www.biorxiv.org www.biorxiv.org
    Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level
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    biorxiv.org/content/10.1101/2023.10.16.562592v1
  158. 52.53.155.43 52.53.155.43
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    52.53.155.43/081c581c43e0c0f25916aa7621bfda2e34b6f467/Molecular Oncology - 2023 - Everest-Dass - Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis -html.html
  159. www.biorxiv.org www.biorxiv.org
    Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination
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  160. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
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  161. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
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  162. www.nature.com www.nature.com
    Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction
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    nature.com/articles/s41401-023-01163-x
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a new Adar1p150−/− mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis
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  164. www.sciencedirect.com www.sciencedirect.com
    Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein (RNP) to inhibit herpes simplex virus1 infection in vitro and in vivo
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  165. www.sciencedirect.com www.sciencedirect.com
    Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
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  166. www.mdpi.com www.mdpi.com
    In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA
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  167. www.sciencedirect.com www.sciencedirect.com
    Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8
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  168. www.sciencedirect.com www.sciencedirect.com
    The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2
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  169. www.sciencedirect.com www.sciencedirect.com
    Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs
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  170. www.sciencedirect.com www.sciencedirect.com
    Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness
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  171. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  172. www.biorxiv.org www.biorxiv.org
    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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  173. www.sciencedirect.com www.sciencedirect.com
    TET3 plays a critical role in white adipose development and diet-induced remodeling
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex
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  175. www.cell.com www.cell.com
    Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
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    cell.com/immunity/abstract/S1074-7613(23)00367-9
  176. www.sciencedirect.com www.sciencedirect.com
    TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimizing Bioink Composition for Human Chondrocyte Expression of Lubricin
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9-Mediated CtBP1 Gene Editing Enhances Chemosensitivity and Inhibits Metastatic Potential in Esophageal Squamous Cell Carcinoma Cells
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase Activity Regulates Cystine Starvation Induced Ferroptosis through Malic Enzyme 1 in Pancreatic Cancer Cells
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  180. Sep 2023
  181. www.sciencedirect.com www.sciencedirect.com
    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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  182. www.biorxiv.org www.biorxiv.org
    Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes
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  183. www.sciencedirect.com www.sciencedirect.com
    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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  184. journals.asm.org journals.asm.org
    Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB
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  185. www.sciencedirect.com www.sciencedirect.com
    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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  187. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential nanoscale organization of excitatory synapses onto excitatory vs inhibitory neurons
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAP1 promotes osteoclast function by metabolic reprogramming
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing
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  191. 52.53.155.43 52.53.155.43
    vdad120-html.html
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes
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  194. www.nature.com www.nature.com
    HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer
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  196. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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  197. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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  198. www.nature.com www.nature.com
    m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
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  199. link.springer.com link.springer.com
    Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization
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      DOI: 10.1007/s13402-023-00867-w

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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signaling
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      Addgene #12260

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