1,756 Matching Annotations
  1. Oct 2022
  2. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
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    1. scibot 26 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111561

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    sciencedirect.com/science/article/pii/S221112472201422X
  3. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
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    1. scibot 20 Oct 2022
      plasmid_12260

      DOI: 10.1016/j.celrep.2022.111514

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    sciencedirect.com/science/article/pii/S221112472201364X
  4. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    1. scibot 15 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1007/s00018-022-04586-7

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    link.springer.com/article/10.1007/s00018-022-04586-7
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
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    1. scibot 12 Oct 2022
      Addgene_12260

      DOI: 10.1158/2643-3230.BCD-21-0115

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414116/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
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    1. scibot 12 Oct 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
    1
    1. scibot 12 Oct 2022
      plasmid_12260

      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  8. www.nature.com www.nature.com
    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
    1
    1. scibot 11 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41587-022-01494-w

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    nature.com/articles/s41587-022-01494-w
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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
    1
    1. scibot 09 Oct 2022
      RRID:Addgene_1226

      DOI: 10.1016/j.cell.2022.09.020

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    sciencedirect.com/science/article/pii/S0092867422011928
  10. www.nature.com www.nature.com
    Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression
    1
    1. scibot 08 Oct 2022
      Plasmid_12260

      DOI: 10.1038/s41596-022-00741-3

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    nature.com/articles/s41596-022-00741-3
  11. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
    1
    1. scibot 07 Oct 2022
      Cat#12260

      DOI: 10.1016/j.molcel.2022.09.007

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    sciencedirect.com/science/article/pii/S1097276522008966
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells
    1
    1. scibot 07 Oct 2022
      RRID:Addgene_12260

      DOI: 10.3389/fcell.2022.929495

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    ncbi.nlm.nih.gov/pmc/articles/PMC9527304/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
    1
    1. scibot 02 Oct 2022
      RRID:Addgene_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
  14. Sep 2022
  15. www.sciencedirect.com www.sciencedirect.com
    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
    1
    1. scibot 30 Sep 2022
      AddGene#12260

      DOI: 10.1016/j.immuni.2022.09.001

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    sciencedirect.com/science/article/pii/S1074761322004149
  16. www.sciencedirect.com www.sciencedirect.com
    Opto-katanin, an optogenetic tool for localized, microtubule disassembly
    1
    1. scibot 29 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.cub.2022.09.010

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    sciencedirect.com/science/article/pii/S0960982222014543
  17. www.sciencedirect.com www.sciencedirect.com
    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
    1
    1. scibot 29 Sep 2022
      plasmid_12260

      DOI: 10.1016/j.devcel.2022.09.003

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    sciencedirect.com/science/article/pii/S1534580722006335
  18. www.sciencedirect.com www.sciencedirect.com
    The lncRNA ALPHA specifically targets chikungunya virus to control infection
    1
    1. scibot 27 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2022.08.030

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    sciencedirect.com/science/article/pii/S1097276522008504
  19. www.sciencedirect.com www.sciencedirect.com
    A screening-compatible live cell fluorescence resonance energy transfer-based assay for modulation of Rho GTPase activity
    1
    1. scibot 24 Sep 2022
      Addgene_12260

      DOI: 10.1016/j.xpro.2022.101705

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    sciencedirect.com/science/article/pii/S2666166722005858
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study
    1
    1. scibot 22 Sep 2022
      Addgene_12260

      DOI: 10.4274/jtgga.galenos.2022.2022-1-14

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    ncbi.nlm.nih.gov/pmc/articles/PMC9450920/
  21. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
    1
    1. scibot 22 Sep 2022
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      DOI: 10.1242/jcs.258396

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    journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
  22. www.sciencedirect.com www.sciencedirect.com
    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
    2
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111344

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    2. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111344

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    sciencedirect.com/science/article/pii/S221112472201172X
  23. www.sciencedirect.com www.sciencedirect.com
    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
    1
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111361

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    sciencedirect.com/science/article/pii/S2211124722011937
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
    1
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1136/gutjnl-2021-324994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation
    1
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.3389/fendo.2022.932286

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    ncbi.nlm.nih.gov/pmc/articles/PMC9483015/
  26. www.sciencedirect.com www.sciencedirect.com
    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
    1
    1. scibot 21 Sep 2022
      Plasmid - psPAX2

      DOI: 10.1016/j.celrep.2022.111390

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    sciencedirect.com/science/article/pii/S221112472201227X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
    1
    1. scibot 21 Sep 2022
      plasmid_12260

      DOI: 10.1371/journal.pbio.3001754

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    ncbi.nlm.nih.gov/pmc/articles/PMC9469972/
  28. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
    1
    1. scibot 20 Sep 2022
      Addgene plasmid #12260

      DOI: 10.1016/j.xpro.2022.101682

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    sciencedirect.com/science/article/pii/S2666166722005627
  29. www.sciencedirect.com www.sciencedirect.com
    Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells
    1
    1. scibot 15 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2022.101675

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    sciencedirect.com/science/article/pii/S266616672200555X
  30. www.sciencedirect.com www.sciencedirect.com
    SerpinB3 drives cancer stem cell survival in glioblastoma
    1
    1. scibot 15 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111348

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    sciencedirect.com/science/article/pii/S2211124722011767
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
    1
    1. scibot 15 Sep 2022
      RRID:Addgene_12

      DOI: 10.1111/cas.15558

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    onlinelibrary.wiley.com/doi/10.1111/cas.15558
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer
    1
    1. scibot 14 Sep 2022
      RRID:Addgene_12260

      DOI: 10.3390/cancers14174219

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    ncbi.nlm.nih.gov/pmc/articles/PMC9454869/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
    1
    1. scibot 10 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1158/2159-8290.CD-22-0043

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    ncbi.nlm.nih.gov/pmc/articles/PMC9437572/
  34. www.sciencedirect.com www.sciencedirect.com
    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
    1
    1. scibot 08 Sep 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2022.111315

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    sciencedirect.com/science/article/pii/S2211124722011391
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human coronaviruses disassemble processing bodies
    1
    1. scibot 07 Sep 2022
      Addgene_12260

      DOI: 10.1371/journal.ppat.1010724

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    ncbi.nlm.nih.gov/pmc/articles/PMC9439236/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
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      RRID:Addgene_12260

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  37. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
    1
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      DOI: 10.1158/2767-9764.CRC-22-0270

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    aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
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    1. scibot 02 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1128/mbio.01456-22

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    ncbi.nlm.nih.gov/pmc/articles/PMC9426521/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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      RRID:Addgene_12260

      DOI: 10.1128/mbio.01055-22

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    ncbi.nlm.nih.gov/pmc/articles/PMC9426523/
  40. www.sciencedirect.com www.sciencedirect.com
    Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy
    1
    1. scibot 01 Sep 2022
      plasmid_12260

      DOI: 10.1016/j.heliyon.2022.e10483

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    sciencedirect.com/science/article/pii/S2405844022017716
  41. Aug 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
    1
    1. scibot 31 Aug 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.111296

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    sciencedirect.com/science/article/pii/S2211124722011160
  43. www.sciencedirect.com www.sciencedirect.com
    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
    1
    1. scibot 31 Aug 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2022.111293

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    sciencedirect.com/science/article/pii/S2211124722011135
  44. www.sciencedirect.com www.sciencedirect.com
    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    1. scibot 31 Aug 2022
      plasmid_12260

      DOI: 10.1016/j.celrep.2022.111288

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    sciencedirect.com/science/article/pii/S2211124722011081
  45. www.sciencedirect.com www.sciencedirect.com
    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    S146L in MYC is a context-dependent activating substitution in cancer development
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    Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites
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  48. 52.53.155.43 52.53.155.43
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  49. 52.53.155.43 52.53.155.43
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions
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    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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    RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of mycobacterium tuberculosis antigen-specific CD4+ T cell responses restricted by single HLA class II allotype in an individual
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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  60. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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  61. journals.plos.org journals.plos.org
    Genome-wide screening identified SEC61A1 as an essential factor for mycolactone-dependent apoptosis in human premonocytic THP-1 cells
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains
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  63. www.nature.com www.nature.com
    Identifying cell receptors for the nanoparticle protein corona using genome screens
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  64. www.sciencedirect.com www.sciencedirect.com
    Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Scaffold‐Based Multimerization of Soluble ACE2 Efficiently Blocks SARS‐CoV‐2 Infection In Vitro and In Vivo
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL
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  67. rupress.org rupress.org
    Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activity
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    METTL14-dependent m6A modification controls iNKT cell development and function
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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  71. Jul 2022
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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  73. www.sciencedirect.com www.sciencedirect.com
    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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  74. 52.53.155.43 52.53.155.43
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  75. 52.53.155.43 52.53.155.43
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  76. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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  77. 52.53.155.43 52.53.155.43
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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  79. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  80. www.sciencedirect.com www.sciencedirect.com
    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the transcriptional activity of STAT3 by a novel fusion protein
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  84. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  85. Jun 2022
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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  87. 52.53.155.43 52.53.155.43
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  88. 52.53.155.43 52.53.155.43
    mcr-22-0111-html.html
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  89. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
    1
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  90. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    1. scibot 25 Jun 2022
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  91. link.springer.com link.springer.com
    Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
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  92. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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  93. www.sciencedirect.com www.sciencedirect.com
    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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  96. www.sciencedirect.com www.sciencedirect.com
    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
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  97. www.sciencedirect.com www.sciencedirect.com
    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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    1. scibot 15 Jun 2022
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  99. www.nature.com www.nature.com
    RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
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  100. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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  101. www.sciencedirect.com www.sciencedirect.com
    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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    Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD
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  103. www.sciencedirect.com www.sciencedirect.com
    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
    2
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    sciencedirect.com/science/article/pii/S1097276522004439
  104. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
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      DOI: 10.1158/2326-6066.CIR-21-0754

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  107. www.sciencedirect.com www.sciencedirect.com
    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
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  108. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  109. May 2022
  110. link.springer.com link.springer.com
    Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation
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      DOI: 10.1007/s00018-022-04312-3

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  111. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
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  112. www.sciencedirect.com www.sciencedirect.com
    Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies
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  113. www.sciencedirect.com www.sciencedirect.com
    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    sciencedirect.com/science/article/pii/S1934590922001709
  114. www.sciencedirect.com www.sciencedirect.com
    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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  115. www.sciencedirect.com www.sciencedirect.com
    F-box protein FBXO41 suppresses breast cancer growth by inducing autophagic cell death through facilitating proteasomal degradation of oncogene SKP2
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
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      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-21-0810

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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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  118. www.sciencedirect.com www.sciencedirect.com
    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
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  119. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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  120. www.sciencedirect.com www.sciencedirect.com
    Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
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  122. www.nature.com www.nature.com
    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
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  123. www.sciencedirect.com www.sciencedirect.com
    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
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  125. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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  126. www.sciencedirect.com www.sciencedirect.com
    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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  127. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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  128. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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  129. www.nature.com www.nature.com
    Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
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  130. www.sciencedirect.com www.sciencedirect.com
    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    1. scibot 11 May 2022
      Addgene12260

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    sciencedirect.com/science/article/pii/S2211124722005642
  131. www.sciencedirect.com www.sciencedirect.com
    SETD4-mediated KU70 methylation suppresses apoptosis
    1
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      Addgene, Cat#12260

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    sciencedirect.com/science/article/pii/S2211124722005617
  132. www.sciencedirect.com www.sciencedirect.com
    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
    1
    1. scibot 11 May 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2211124722005599
  133. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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    1. scibot 11 May 2022
      Addgene: #12260

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    sciencedirect.com/science/article/pii/S1074761322001777
  134. aacrjournals.org aacrjournals.org
    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
    1
    1. scibot 10 May 2022
      Addgene_12260

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    aacrjournals.org/cancerrescommun/article/2/5/293/696275/Repurposing-Itraconazole-and-Hydroxychloroquine-to
  135. www.science.org www.science.org
    Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
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    1. scibot 10 May 2022
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    science.org/doi/full/10.1126/sciadv.abn2748
  136. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
    1
    1. scibot 10 May 2022
      Plasmid_12260

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    nature.com/articles/s41420-022-01044-y
  137. www.sciencedirect.com www.sciencedirect.com
    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
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    1. scibot 04 May 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S0092867422004433
  138. www.nature.com www.nature.com
    Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
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    nature.com/articles/s41467-022-29942-w
  139. Apr 2022
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  141. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
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    1. scibot 23 Apr 2022
      RRID:Addgene_12260

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    nature.com/articles/s41392-022-00946-8
  142. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
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    1. scibot 22 Apr 2022
      Addgene plasmid #12260

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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  143. www.sciencedirect.com www.sciencedirect.com
    Establishing transgenic murine esophageal organoids
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    1. scibot 22 Apr 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2666166722001976
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
    1
    1. scibot 22 Apr 2022
      plasmid_12260

      DOI: 10.3389/fonc.2022.766794

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    ncbi.nlm.nih.gov/pmc/articles/PMC9015667/
  145. www.sciencedirect.com www.sciencedirect.com
    In vitro and in vivo assay of the ER lipid scramblase TMEM41B
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    1. scibot 21 Apr 2022
      Addgene Cat# 12260

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    sciencedirect.com/science/article/pii/S2666166722002131
  146. www.sciencedirect.com www.sciencedirect.com
    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
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    1. scibot 21 Apr 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S1550413122001267
  147. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    1. scibot 21 Apr 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S1534580722002295
  148. www.sciencedirect.com www.sciencedirect.com
    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    1. scibot 21 Apr 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S1097276522002696
  149. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    1. scibot 21 Apr 2022
      Plasmid_12260

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    sciencedirect.com/science/article/pii/S0092867422003403
  150. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
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    1. scibot 20 Apr 2022
      Addgene12260

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    sciencedirect.com/science/article/pii/S2211124722004545
  151. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
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    1. scibot 20 Apr 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2211124722004508
  152. www.sciencedirect.com www.sciencedirect.com
    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    1. scibot 15 Apr 2022
      AddgeneCat#12260

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    sciencedirect.com/science/article/pii/S2211124722004223
  153. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    2
    1. scibot 15 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.03.008

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      RRID: Addgene_12260

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    sciencedirect.com/science/article/pii/S1535610822001234
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
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    1. scibot 14 Apr 2022
      Addgene_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC8926873/
  155. www.sciencedirect.com www.sciencedirect.com
    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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    sciencedirect.com/science/article/pii/S2211124722004259
  156. www.sciencedirect.com www.sciencedirect.com
    Rapid establishment of human colonic organoid knockout lines
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    1. scibot 14 Apr 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S2666166722001885
  157. www.sciencedirect.com www.sciencedirect.com
    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    1. scibot 14 Apr 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S2211124722003199
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs
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    1. scibot 14 Apr 2022
      RRID:Addgene_12

      DOI: 10.1016/j.biomaterials.2022.121509

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    ncbi.nlm.nih.gov/pmc/articles/PMC8999341/
  159. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
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      Plasmid_12260

      DOI: 10.1016/j.ccell.2022.03.006

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    sciencedirect.com/science/article/pii/S1535610822001210
  160. www.sciencedirect.com www.sciencedirect.com
    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    1. scibot 13 Apr 2022
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S1074761322001303
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
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    1. scibot 13 Apr 2022
      RRID:Addgene_12260

      DOI: 10.3389/fgeed.2022.803375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8995503/
  162. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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    1. scibot 07 Apr 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2211124722003898
  163. www.sciencedirect.com www.sciencedirect.com
    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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    1. scibot 07 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2022.03.016

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    sciencedirect.com/science/article/pii/S1097276522002544
  164. aacrjournals.org aacrjournals.org
    GFI1 cooperates with IKZF1/IKAROS to activate gene expression in T-cell acute lymphoblastic leukemia
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    1. scibot 05 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1158/1541-7786.MCR-21-0352

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    aacrjournals.org/mcr/article/20/4/501/682307/GFI1-Cooperates-with-IKZF1-IKAROS-to-Activate-Gene
  165. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:Addgene_12260

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763
  166. Mar 2022
  167. elifesciences.org elifesciences.org
    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
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    1. scibot 31 Mar 2022
      RRID:Addgene_12260

      DOI: 10.7554/eLife.69229

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    elifesciences.org/articles/69229
  168. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
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    1. scibot 31 Mar 2022
      RRID:Addgene_12260

      DOI: 10.1093/nar/gkac178

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac178/6553119
  169. www.sciencedirect.com www.sciencedirect.com
    Genome-wide analysis of haploinsufficiency in human embryonic stem cells
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    1. scibot 30 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722003175
  170. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
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    1. scibot 30 Mar 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.110559

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    sciencedirect.com/science/article/pii/S2211124722003035
  171. www.sciencedirect.com www.sciencedirect.com
    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    sciencedirect.com/science/article/pii/S1097276522002192
  172. www.sciencedirect.com www.sciencedirect.com
    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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  173. www.sciencedirect.com www.sciencedirect.com
    A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis
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    1. scibot 27 Mar 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.chembiol.2022.03.006

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    sciencedirect.com/science/article/pii/S2451945622000940
  174. www.sciencedirect.com www.sciencedirect.com
    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
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      Addgene_12260

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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
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  176. 52.53.155.43 52.53.155.43
    Optochemical Control of mTOR Signaling and mTOR-Dependent Autophagy
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  177. www.sciencedirect.com www.sciencedirect.com
    The mTOR chromatin-bound interactome in prostate cancer
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants
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  179. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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  180. www.sciencedirect.com www.sciencedirect.com
    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
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  181. www.embopress.org www.embopress.org
    CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia
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  182. www.sciencedirect.com www.sciencedirect.com
    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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  183. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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  184. www.sciencedirect.com www.sciencedirect.com
    Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
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  185. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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  186. www.sciencedirect.com www.sciencedirect.com
    Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms
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    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
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  188. www.sciencedirect.com www.sciencedirect.com
    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
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    Local hyperthermia therapy induces browning of white fat and treats obesity
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  192. www.nature.com www.nature.com
    Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
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  193. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
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  197. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
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  198. www.sciencedirect.com www.sciencedirect.com
    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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    Recruitment of DNA to tumor-derived microvesicles
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  201. Feb 2022
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    Generation of a pooled shRNA library for functional genomics screens
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