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Nov 2021
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Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments

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The Extensive and Expensive Impacts of HEp-2 [HeLa], Intestine 407 [HeLa], and Other False Cell Lines in Journal Publications - Christopher T. Korch, Amanda Capes-Davis, 2021

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AKIRIN2 controls the nuclear import of proteasomes in vertebrates

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circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing

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ncbi.nlm.nih.gov/pmc/articles/PMC8550772/
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The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7

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Oct 2021
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The Extensive and Expensive Impacts of HEp-2 [HeLa], Intestine 407 [HeLa], and Other False Cell Lines in Journal Publications - Christopher T. Korch, Amanda Capes-Davis, 2021

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Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells

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nature.com/articles/s41596-021-00614-1
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Purification of infection-associated macropinosomes by magnetic isolation for proteomic characterization

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nature.com/articles/s41596-021-00610-5
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Capture of the newly transcribed RNA interactome using click chemistry

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Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers

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onlinelibrary.wiley.com/doi/full/10.1002/ijc.33832
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Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

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Mechanistic Insights into COVID-19 by Global Analysis of the SARS-CoV-2 3CLpro Substrate Degradome

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ncbi.nlm.nih.gov/pmc/articles/PMC8501228/
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Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

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ncbi.nlm.nih.gov/pmc/articles/PMC8523161/
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Glycogen accumulation and phase separation drives liver tumor initiation

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sciencedirect.com/science/article/pii/S0092867421011752
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Screening compound libraries for H2O2-mediated cancer therapeutics using a peroxiredoxin-based sensor

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1. scibot 22 Oct 2021
  
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sciencedirect.com/science/article/pii/S2451945621004347
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PUPIL enables mapping and stamping of transient electrical connectivity in developing nervous systems

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Lysosomal Zn2+ release triggers rapid, mitochondria-mediated, non-apoptotic cell death in metastatic melanoma

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1. scibot 21 Oct 2021
  
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Delineating the Switch between Senescence and Apoptosis in Cervical Cancer Cells under Ciclopirox Treatment

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1. scibot 15 Oct 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8508512/
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Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome

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USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork

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Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

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Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines

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ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
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S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity

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ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy

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Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics

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Sep 2021
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Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15630
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DNA-guided photoactivatable probe-based chemical proteomics reveals the reader protein of mRNA methylation

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ncbi.nlm.nih.gov/pmc/articles/PMC8441146/
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SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways

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science.org/doi/10.1126/scisignal.abc7611
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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

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Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

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Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism

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Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration

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Light-Inducible Spatio-Temporal Control of TLR4 and NF-κB-Gluc Reporter in Human Pancreatic Cell Line

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ncbi.nlm.nih.gov/pmc/articles/PMC8431472/
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Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter

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Genetically Encoded Protein Thermometer Enables Precise Electrothermal Control of Transgene Expression

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Controlled lipid β-oxidation and carnitine biosynthesis by a vitamin D metabolite

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Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations

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HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis

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Applicability of Scrape Loading-Dye Transfer Assay for Non-Genotoxic Carcinogen Testing

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GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility

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Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint

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High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment

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A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication

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Structured elements drive extensive circular RNA translation

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A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells

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Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

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Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection

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Characterizing microRNA-mediated modulation of gene expression noise and its effect on synthetic gene circuits

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Quantitative control of noise in mammalian gene expression by dynamic histone regulation

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A light-switching pyrene probe to detect phase separated biomolecules

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HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization

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Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition

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Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation

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Phosphorylation of Trans-active response DNA binding protein-of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing

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Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation

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Inhibitor of ppGalNAc-T3-mediated O-glycosylation blocks cancer cell invasiveness and lowers FGF23 levels

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NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells

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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation

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Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6

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Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection

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Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection

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The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity

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Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

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Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer

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Acetylation of Cytidine in mRNA Promotes Translation Efficiency

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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

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Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization

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MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

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CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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Localized Intercellular Transfer of Ephrin-As by Trans-endocytosis Enables Long-Term Signaling

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A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice

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Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis

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Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader

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PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin

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The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1

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Exon-Mediated Activation of Transcription Starts

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Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops

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Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems

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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering

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SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance

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PCNA Unloading Is Negatively Regulated by BET Proteins

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KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis

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ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response

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  DOI: 10.1016/j.celrep.2019.09.008
  
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Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons

1
1. scibot 30 Jul 2021
  
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  HeLa cell line
  
  DOI: 10.1016/j.celrep.2019.09.018
  
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AUTACs: Cargo-Specific Degraders Using Selective Autophagy

1
1. scibot 30 Jul 2021
  
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.09.009
  
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Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2

1
1. scibot 30 Jul 2021
  
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  HeLa
  
  DOI: 10.1016/j.celrep.2019.08.087
  
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A Consensus Binding Motif for the PP4 Protein Phosphatase

1
1. scibot 30 Jul 2021
  
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.08.029
  
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Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

1
1. scibot 30 Jul 2021
  
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  Hela
  
  DOI: 10.7554/eLife.48119
  
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Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase

1
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.08.021
  
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Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons

1
1. scibot 30 Jul 2021
  
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  Human: HeLa
  
  DOI: 10.1016/j.stem.2019.08.013
  
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Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics

1
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.08.018
  
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Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

1
1. scibot 30 Jul 2021
  
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  Human: HeLa cells
  
  DOI: 10.1016/j.chom.2019.08.017
  
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sciencedirect.com/science/article/pii/S1931312819304263
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CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment

1
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  HeLa
  
  DOI: 10.1186/s12915-019-0694-9
  
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link.springer.com/article/10.1186/s12915-019-0694-9
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The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers

1
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  Human:HeLa
  
  DOI: 10.1016/j.chom.2019.08.010
  
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Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling

1
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  HeLa
  
  DOI: 10.1016/j.chembiol.2019.07.010
  
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Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9

1
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Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network

1
1. scibot 30 Jul 2021
  
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.devcel.2018.10.012
  
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Untitled document

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  DOI: 10.7554/eLife.36530
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6086667/
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MAVS O-GlcNAcylation Is Essential for Host Antiviral Immunity against Lethal RNA Viruses

1
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  RRID: CVCL_0030
  
  DOI: 10.1016/j.celrep.2019.07.085
  
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Regulation of Autophagic Flux by the 20S Proteasome

1
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  DOI: 10.1016/j.chembiol.2019.07.002
  
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The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

1
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  RRID: CVCL_0030
  
  DOI: 10.1016/j.cell.2019.05.035
  
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C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex

1
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.06.023
  
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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

1
1. scibot 29 Jul 2021
  
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  Human: HeLa
  
  DOI: 10.1016/j.celrep.2019.07.050
  
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SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing

1
1. scibot 29 Jul 2021
  
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  Human: HeLa
  
  DOI: 10.1016/j.celrep.2019.07.040
  
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TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion

1
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  HeLa
  
  DOI: 10.1016/j.celrep.2019.07.036
  
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Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability

1
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  HeLa
  
  DOI: 10.1016/j.celrep.2019.07.010
  
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Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation

1
1. scibot 29 Jul 2021
  
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  Human: HeLa
  
  DOI: 10.1016/j.celrep.2019.06.048
  
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Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

1
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.06.006
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.060
  
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sciencedirect.com/science/article/pii/S2211124719303900
onlinelibrary.wiley.com onlinelibrary.wiley.com

Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0030
  
  DOI: 10.1111/jnc.15445
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15445
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Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy

1
1. scibot 28 Jul 2021
  
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  RRID:CVCL_0030
  
  DOI: 10.1080/15384047.2018.1504722
  
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tandfonline.com/doi/full/10.1080/15384047.2018.1504722
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Light-Activated ROS Production Induces Synaptic Autophagy

1
1. scibot 28 Jul 2021
  
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  RRID:CVCL_0030
  
  DOI: 10.1523/JNEUROSCI.1317-18.2019
  
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jneurosci.org/content/39/12/2163
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Complement C4 Prevents Viral Infection through Capsid Inactivation

1
1. scibot 28 Jul 2021
  
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  RRID: CVCL_0030
  
  DOI: 10.1016/j.chom.2019.02.016
  
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The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity

1
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  RRID:CVCL_0030
  
  DOI: 10.1016/j.celrep.2018.11.046
  
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sciencedirect.com/science/article/pii/S2211124718318096
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The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes

1
1. scibot 28 Jul 2021
  
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  HeLa
  
  DOI: 10.1016/j.celrep.2019.05.071
  
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sciencedirect.com/science/article/pii/S2211124719307004
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Lysosome Positioning Influences mTORC2 and AKT Signaling

1
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  HeLa
  
  DOI: 10.1016/j.molcel.2019.05.009
  
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sciencedirect.com/science/article/pii/S1097276519303624
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SLC19A1 Is an Importer of the Immunotransmitter cGAMP

1
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  RRID: CVCL_0030
  
  DOI: 10.1016/j.molcel.2019.05.006
  
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HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells

1
1. scibot 28 Jul 2021
  
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  HeLa cells
  
  DOI: 10.1016/j.celrep.2019.03.016
  
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sciencedirect.com/science/article/pii/S2211124719303237
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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

1
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  Human: HeLa
  
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Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms

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In Situ Architecture and Cellular Interactions of PolyQ Inclusions

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2. scibot 28 Jul 2021
  
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A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication

2
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Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

1
1. scibot 27 Jul 2021
  
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  CCL-2
  
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Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2

1
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  CCL-2
  
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Perturbation-Based Proteomic Correlation Profiling as a Target Deconvolution Methodology

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  CCL-2
  
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The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers

1
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  CCL-2
  
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Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

1
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  CCL-2
  
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TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

1
1. scibot 27 Jul 2021
  
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  HeLa cells
  
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Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy

1
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  CCL 2
  
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

1
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  CCL-2
  
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Rapid manipulation of mitochondrial morphology in a living cell with iCMM

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  CCL-2
  
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capCLIP: a new tool to probe translational control in human cells through capture and identification of the eIF4E–mRNA interactome

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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab604/6320419
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Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

2
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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

1
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  CCL-2
  
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Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

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CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells

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Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity

1
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  ATCCCat# CCL-2
  
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A synthetic circuit for buffering gene dosage variation between individual mammalian cells

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Protocol for photoactivation of YAP in cancer cell spheroids embedded in collagen gels

1
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  CCL-2
  
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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

1
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Protocol for nuclear export signal characterization of cGAS in mammalian cells

1
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Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

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Global mapping of Salmonella enterica-host protein-protein interactions during infection

1
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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

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The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

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Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis

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  DOI: 10.1016/j.chembiol.2021.06.003
  
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Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

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1. scibot 01 Jul 2021
  
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  DOI: 10.18632/oncotarget.27989
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
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Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics

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  DOI: 10.1016/j.chembiol.2021.06.002
  
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sciencedirect.com/science/article/pii/S2451945621003019
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The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair

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1. scibot 30 Jun 2021
  
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  CCL-2
  
  DOI: 10.1016/j.celrep.2021.109306
  
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An Hsp90 co-chaperone links protein folding and degradation and is part of a conserved protein quality control

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1. scibot 30 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109328
  
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TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis

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1. scibot 25 Jun 2021
  
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  CCL-2
  
  DOI: 10.1016/j.celrep.2021.109277
  
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cell.com/cell-reports/fulltext/S2211-1247(21)00644-6
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HRMAn 2.0: Next generation artificial intelligence‐driven analysis for broad host‐pathogen interactions

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  DOI: 10.1111/cmi.13349
  
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onlinelibrary.wiley.com/doi/10.1111/cmi.13349
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BPS Publications

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  DOI: 10.1111/bph.15467
  
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On The Mechanism Of Tumor Cell Entry Of Aloe-Emodin, A Natural Compound Endowed With Anticancer Activity

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  DOI: 10.1002/ijc.33686
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33686
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Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage

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  DOI: 10.1016/j.chembiol.2021.05.016
  
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Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter

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  DOI: 10.1016/j.celrep.2021.109275
  
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Light-inducible deformation of mitochondria in live cells

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1. scibot 22 Jun 2021
  
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  DOI: 10.1016/j.chembiol.2021.05.015
  
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LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes

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1. scibot 19 Jun 2021
  
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  CCL-2
  
  DOI: 10.1016/j.cub.2021.05.052
  
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The metabolite 5-methyl-1,3-benzenediol and its derivative methyl-2,4-dihydroxy-6-methylbenzoate from the lichen Parmotrema tinctorum with potent apoptotic and anti-angiogenesis effects

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  DOI: 10.1007/s13205-021-02883-9
  
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