2,087 Matching Annotations
  1. Feb 2024
  2. 52.53.155.43 52.53.155.43
    16a7c226-f27d-4a9e-9485-8d25fbca685c_130126_-_kathleen_southern-html.html
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    52.53.155.43/93e1d16e27c8161612933dea24e99e671d4f6f76/5e876839-9f6f-4bea-9e7d-55aa16426283_130126_-_kathleen_southern-html.html
  3. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17088
  4. aacrjournals.org aacrjournals.org
    First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
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    aacrjournals.org/clincancerres/article/30/3/506/733551/First-in-Human-Study-with-Preclinical-Data-of-BCL
  5. www.nature.com www.nature.com
    Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts
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    nature.com/articles/s43587-024-00575-6
  6. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13613
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
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    Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex
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    sciencedirect.com/science/article/pii/S2211124724001177
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866696/
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    Mouse oocytes sequester aggregated proteins in degradative super-organelles
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    sciencedirect.com/science/article/pii/S0092867424000680
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34883
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17015
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    The sequence of events of enteropathogenic E. coli’s type III secretion system translocon assembly
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    sciencedirect.com/science/article/pii/S2589004224003298
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    sciencedirect.com/science/article/pii/S1534580724000406
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aspartate β-hydroxylase Regulates Expression of Ly6 Genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10861829/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14806
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
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    ncbi.nlm.nih.gov/pmc/articles/PMC10851258/
  18. 52.53.155.43 52.53.155.43
    PIIS2589004224003444-html.html
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    52.53.155.43/b2be18a8a322041c27066db8e254c128d7d10a06/PIIS2589004224003444-html.html
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  20. www.biorxiv.org www.biorxiv.org
    Comparative analysis of methodologies for detecting extrachromosomal circular DNA
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    biorxiv.org/content/10.1101/2023.12.01.569546v1
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    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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    sciencedirect.com/science/article/pii/S2211124724000779
  22. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    sciencedirect.com/science/article/pii/S1097276524000480
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mieap forms membrane-less organelles involved in cardiolipin metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845071/
  24. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17081
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16062
  26. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17064
  27. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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    sciencedirect.com/science/article/pii/S2451945624000382
  28. www.sciencedirect.com www.sciencedirect.com
    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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    sciencedirect.com/science/article/pii/S1097276524000091
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nudt21-mediated alternative polyadenylation of MZT1 3’UTR contributes to pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831950/
  30. www.sciencedirect.com www.sciencedirect.com
    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    sciencedirect.com/science/article/pii/S221112472400024X
  31. Jan 2024
  32. www.sciencedirect.com www.sciencedirect.com
    HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling
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    sciencedirect.com/science/article/pii/S0014482724000399
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Serum Interleukin 10 Levels Are Associated with Increased Disease Activity and Increased Risk of Anti-SS-A/Ro Antibody Positivity in Patients with Systemic Lupus Erythematosus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10296207/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10340532/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PepFect14 mediates the delivery of mRNA into human primary keratinocytes and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10374019/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798561/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction of PINK1 with nucleotides and kinetin
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798554/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
  40. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13577
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H2O2 Activation of Syk/PI3K/Akt Signaling Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788729/
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Arrestin-3 binds parkin and enhances parkin-dependent mitophagy
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16043
  44. link.springer.com link.springer.com
    Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion
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    link.springer.com/article/10.1007/s00018-023-05072-4
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10777466/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated Serum Levels of Soluble Transferrin Receptor Are Associated with an Increased Risk of Cardiovascular, Pulmonary, and Hematological Manifestations and a Decreased Risk of Neuropsychiatric Manifestations in Systemic Lupus Erythematosus Patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10743550/
  48. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13563
  49. www.sciencedirect.com www.sciencedirect.com
    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
  50. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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    52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
  51. Dec 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite
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    sciencedirect.com/science/article/pii/S2589004223026445
  53. www.sciencedirect.com www.sciencedirect.com
    A rapid isothermal CRISPR‒Cas13a diagnostic test for genital Herpes simplex virus infection.
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    sciencedirect.com/science/article/pii/S2589004223026585
  54. www.sciencedirect.com www.sciencedirect.com
    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    sciencedirect.com/science/article/pii/S2211124723015930
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10723637/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10724652/
  57. www.sciencedirect.com www.sciencedirect.com
    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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    sciencedirect.com/science/article/pii/S2451945623004233
  58. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    sciencedirect.com/science/article/pii/S2451945623004257
  59. www.sciencedirect.com www.sciencedirect.com
    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    sciencedirect.com/science/article/pii/S1097276523009607
  60. www.sciencedirect.com www.sciencedirect.com
    SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer
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    sciencedirect.com/science/article/pii/S109727652300919X
  61. www.sciencedirect.com www.sciencedirect.com
    The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation
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    sciencedirect.com/science/article/pii/S0969212623004082
  62. www.sciencedirect.com www.sciencedirect.com
    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
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    sciencedirect.com/science/article/pii/S109727652300967X
  63. link.springer.com link.springer.com
    Investigation of the mixed origins of the MGC-803 cell line reveals that it is a hybrid cell line derived from HeLa
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    link.springer.com/article/10.1007/s13577-023-01011-4
  64. www.sciencedirect.com www.sciencedirect.com
    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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    sciencedirect.com/science/article/pii/S221112472301567X
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10711208/
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The impact of cycling hypoxia on the phenotype of HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29280
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Highlights from MBoC Selection: Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10559312/
  69. www.sciencedirect.com www.sciencedirect.com
    Exploiting the endogenous yeast nuclear proteome to identify short linear motifs in vivo
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    sciencedirect.com/science/article/pii/S2667237523003089
  70. www.biorxiv.org www.biorxiv.org
    Spartin-mediated lipid transfer facilitates lipid droplet turnover
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    biorxiv.org/content/10.1101/2023.11.29.569220v1
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29230
  72. Nov 2023
  73. www.sciencedirect.com www.sciencedirect.com
    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
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    sciencedirect.com/science/article/pii/S2211124723014663
  74. www.sciencedirect.com www.sciencedirect.com
    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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    sciencedirect.com/science/article/pii/S2211124723014961
  75. www.sciencedirect.com www.sciencedirect.com
    Extensive elimination of acinar cells during normal postnatal pancreas growth
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    sciencedirect.com/science/article/pii/S2211124723014699
  76. link.springer.com link.springer.com
    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
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    link.springer.com/article/10.1007/s00018-023-05011-3
  77. www.sciencedirect.com www.sciencedirect.com
    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
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    sciencedirect.com/science/article/pii/S1097276521001714
  78. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    sciencedirect.com/science/article/pii/S2451945623003719
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
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    ncbi.nlm.nih.gov/pmc/articles/PMC10150294/
  82. www.sciencedirect.com www.sciencedirect.com
    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
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    sciencedirect.com/science/article/pii/S2211124723013700
  83. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pohlers - Th17 cells target the metabolic miR‐142‐5p succinate dehydrogenase subunit C D SDHC-html.html
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    52.53.155.43/a186f6fbd2a3289ac6933335bf9b0efbe74c0f93/Molecular Oncology - 2023 - Pohlers - Th17 cells target the metabolic miR-142-5p succinate dehydrogenase subunit C D SDHC-html.html
  84. www.embopress.org www.embopress.org
    Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
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    embopress.org/doi/10.15252/msb.202311782
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
  86. Oct 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10611716/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts
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