1,170 Matching Annotations
  1. Feb 2021
  2. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer
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    bmccancer.biomedcentral.com/article/10.1186/s12885-021-07900-x
  3. elifesciences.org elifesciences.org
    p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
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    elifesciences.org/articles/31723
  4. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of immune cell metabolism by cancer cell oncogenic mutations
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32888
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    Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy
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    sciencedirect.com/science/article/pii/S0753332219352709
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single‐Cell Analysis of Transcriptome and Telomeres
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    onlinelibrary.wiley.com/doi/10.1002/advs.202004320
  8. elifesciences.org elifesciences.org
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
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    elifesciences.org/articles/61797
  9. Jan 2021
  10. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer
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    sciencedirect.com/science/article/pii/S221112472031665X
  11. www.nature.com www.nature.com
    Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells
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    nature.com/articles/s41596-020-00454-5
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    Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes
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    sciencedirect.com/science/article/pii/S2666166720302641
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    Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation
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    sciencedirect.com/science/article/pii/S2211124720316247
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    Prolonged mitosis causes separase deregulation and chromosome nondisjunction
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    sciencedirect.com/science/article/pii/S2211124720316417
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polyphenolic Fraction Obtained From Thalassia testudinum Marine Plant and Thalassiolin B Exert Cytotoxic Effects in Colorectal Cancer Cells and Arrest Tumor Progression in a Xenograft Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7774314/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7773337/
  17. Dec 2020
  18. www.sciencedirect.com www.sciencedirect.com
    Cetuximab enhances the anti-tumor function of macrophages in an IL-6 dependent manner
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    sciencedirect.com/science/article/pii/S0024320520317136
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7695693/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Gracillin shows potent efficacy against colorectal cancer through inhibiting the STAT3 pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/jcmm.16134
  21. www.sciencedirect.com www.sciencedirect.com
    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease
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    sciencedirect.com/science/article/pii/S2211124720314078
  22. www.embopress.org www.embopress.org
    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
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    embopress.org/doi/abs/10.15252/embj.2019103654
  23. Nov 2020
  24. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12821
  25. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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    pubmed.ncbi.nlm.nih.gov/33147457/
  26. www.sciencedirect.com www.sciencedirect.com
    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
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    sciencedirect.com/science/article/pii/S221112472031336X
  27. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity
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    cancerci.biomedcentral.com/article/10.1186/s12935-020-01598-w
  28. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
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    pubmed.ncbi.nlm.nih.gov/33108759/
  29. Oct 2020
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin D as a Primer for Oncolytic Viral Therapy in Colon Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC7582493/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7584667/
  32. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
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    pubmed.ncbi.nlm.nih.gov/33027658/
  33. Sep 2020
  34. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress
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    pubmed.ncbi.nlm.nih.gov/32966795/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
  36. www.nature.com www.nature.com
    Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer
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    nature.com/articles/s41388-020-01416-7
  37. www.sciencedirect.com www.sciencedirect.com
    Serine Catabolism Feeds NADH when Respiration Is Impaired
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    sciencedirect.com/science/article/pii/S1550413120301145
  38. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
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    pubmed.ncbi.nlm.nih.gov/32966794/
  39. www.sciencedirect.com www.sciencedirect.com
    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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    sciencedirect.com/science/article/pii/S1550413120301881
  40. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12600@10.1002/(ISSN)1878-0261.world-cancer-day-2020
  41. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
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    elifesciences.org/articles/58828
  42. www.cell.com www.cell.com
    Gene-Specific Control of tRNA Expression by RNA Polymerase II
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30191-X
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    Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling
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    sciencedirect.com/science/article/pii/S2352396420301754
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GC content shapes mRNA storage and decay in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6944446/
  45. www.sciencedirect.com www.sciencedirect.com
    Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53
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    sciencedirect.com/science/article/pii/S2211124719317218
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15149
  47. link.springer.com link.springer.com
    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
  48. www.sciencedirect.com www.sciencedirect.com
    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
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    sciencedirect.com/science/article/pii/S2211124720304332
  49. mct.aacrjournals.org mct.aacrjournals.org
    Novel Miniaturized Drug Conjugate Leverages HSP90 Driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors
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    mct.aacrjournals.org/content/19/8/1613
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β‐catenin signaling
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33036
  51. www.sciencedirect.com www.sciencedirect.com
    HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation
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    sciencedirect.com/science/article/pii/S2211124720306756
  52. www.sciencedirect.com www.sciencedirect.com
    Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer
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    sciencedirect.com/science/article/pii/S221112472030560X
  53. www.sciencedirect.com www.sciencedirect.com
    FBXW7 Confers Radiation Survival by Targeting p53 for Degradation
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    sciencedirect.com/science/article/pii/S2211124719316821
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32955
  55. www.sciencedirect.com www.sciencedirect.com
    Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
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    sciencedirect.com/science/article/pii/S2211124720308111
  56. www.cell.com www.cell.com
    NF-κB Dynamics Discriminate between TNF Doses in Single Cells
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    cell.com/cell-systems/abstract/S2405-4712(17)30448-9
  57. link.springer.com link.springer.com
    Roles of DANCR/microRNA-518a-3p/MDMA ceRNA network in the growth and malignant behaviors of colon cancer cells
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    link.springer.com/article/10.1186/s12885-020-06856-8
  58. www.mdpi.com www.mdpi.com
    The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model
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    mdpi.com/2072-6694/12/4/853
  59. www.sciencedirect.com www.sciencedirect.com
    Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation
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    sciencedirect.com/science/article/pii/S2211124720306343
  60. www.mdpi.com www.mdpi.com
    Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP
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    mdpi.com/2073-4409/9/8/1760
  61. www.sciencedirect.com www.sciencedirect.com
    Systematic Analysis of Targets of Pumilio-Mediated mRNA Decay Reveals that PUM1 Repression by DNA Damage Activates Translesion Synthesis
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    sciencedirect.com/science/article/pii/S2211124720304423
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    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes
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    sciencedirect.com/science/article/pii/S1097276520302318
  63. www.sciencedirect.com www.sciencedirect.com
    TFIID Enables RNA Polymerase II Promoter-Proximal Pausing
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    sciencedirect.com/science/article/pii/S1097276520301568
  64. www.sciencedirect.com www.sciencedirect.com
    DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex
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    sciencedirect.com/science/article/pii/S1097276520301921
  65. www.sciencedirect.com www.sciencedirect.com
    Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
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    sciencedirect.com/science/article/pii/S1097276520301520
  66. www.sciencedirect.com www.sciencedirect.com
    KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs
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    sciencedirect.com/science/article/pii/S1097276520302665
  67. www.mdpi.com www.mdpi.com
    Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling
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    mdpi.com/1422-0067/21/5/1773
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    A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging
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    sciencedirect.com/science/article/pii/S0092867420301562
  69. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Identification and Target-Modification of SL-BBI: A Novel Bowman–Birk Type Trypsin Inhibitor from Sylvirana latouchii
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    pubmed.ncbi.nlm.nih.gov/32872343/
  70. www.nature.com www.nature.com
    Systematic quantitative analysis of ribosome inventory during nutrient stress
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    nature.com/articles/s41586-020-2446-y
  71. www.nature.com www.nature.com
    The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach
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    nature.com/articles/s41598-020-62293-4
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cotargeting BET proteins overcomes resistance arising from PI3K/mTOR blockade‐induced protumorigenic senescence in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33047
  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14981
  74. elifesciences.org elifesciences.org
    RNA-guided retargeting of Sleeping Beauty transposition in human cells
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    elifesciences.org/articles/53868
  75. www.sciencedirect.com www.sciencedirect.com
    Distinct Mechanisms of Resistance to a CENP-E Inhibitor Emerge in Near-Haploid and Diploid Cancer Cells
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    sciencedirect.com/science/article/pii/S2451945620301495
  76. www.sciencedirect.com www.sciencedirect.com
    ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition
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    sciencedirect.com/science/article/pii/S2211124720310858
  77. mcb.asm.org mcb.asm.org
    Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquitinated proteins and RA190 cytotoxicity
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    mcb.asm.org/content/40/18/e00122-20
  78. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Transcriptome Analysis of Colon Cancer Cell Response to 5-Fluorouracil-Induced DNA Damage
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    sciencedirect.com/science/article/pii/S2211124720310627
  79. www.sciencedirect.com www.sciencedirect.com
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
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    sciencedirect.com/science/article/pii/S2211124720308767
  80. www.cell.com www.cell.com
    Structure of the Inhibited State of the Sec Translocon
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30398-1
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32845
  82. elifesciences.org elifesciences.org
    The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells
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    elifesciences.org/articles/44525
  83. Aug 2020
  84. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Integrin-Linked-Kinase Overexpression Is Implicated in Mechanisms of Genomic Instability in Human Colorectal Cancer
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    pubmed.ncbi.nlm.nih.gov/32495257/
  85. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
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    cancerres.aacrjournals.org/content/80/2/334
  86. Jan 2020
  87. www.sciencedirect.com www.sciencedirect.com
    Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome
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    sciencedirect.com/science/article/pii/S2451945619302491
  88. www.sciencedirect.com www.sciencedirect.com
    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
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    sciencedirect.com/science/article/pii/S2451945619303927
  89. elifesciences.org elifesciences.org
    Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation
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    elifesciences.org/articles/45068
  90. www.sciencedirect.com www.sciencedirect.com
    PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia
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    sciencedirect.com/science/article/pii/S1097276519307233
  91. www.mdpi.com www.mdpi.com
    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
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    mdpi.com/2072-6694/11/10/1456
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    Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators
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    sciencedirect.com/science/article/pii/S221112471931099X
  93. www.sciencedirect.com www.sciencedirect.com
    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
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    sciencedirect.com/science/article/pii/S1550413119305121
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Chirality‐Dependent Action of Vitamin C in Suppressing KRAS Mutant Tumor Growth by the Oxidative Combination: Rationale for Cancer Therapeutics
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32658
  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CD16‐158‐Valine Chimeric Receptor T Cells Overcome the Resistance of Kras‐Mutated Colorectal Carcinoma Cells to Cetuximab
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