3,099 Matching Annotations
  1. Mar 2024
  2. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
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    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    embopress.org/doi/10.1038/s44318-024-00043-2
  4. pubs.acs.org pubs.acs.org
    Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region
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    pubs.acs.org/doi/10.1021/acs.jmedchem.3c01549
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    Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder
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    sciencedirect.com/science/article/pii/S2211124724002742
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    DDX3 regulates cancer immune surveillance via 3′ UTR-mediated cell-surface expression of PD-L1
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    sciencedirect.com/science/article/pii/S2211124724002651
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    Role of CD4+ T-cells for regulating splenic myelopoiesis and monocyte differentiation after experimental myocardial infarction
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    link.springer.com/article/10.1007/s00395-024-01035-3
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    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
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    sciencedirect.com/science/article/pii/S1074761324000840
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926899/
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    PUS1 regulates erythropoiesis via tRNA pseudouridylation and cytoplasmic translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10915626/
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    Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes
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    biorxiv.org/content/10.1101/2024.02.28.582570v1
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    CD8+ T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance
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    sciencedirect.com/science/article/pii/S2211124724002158
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    Combinatorial selective ER-phagy remodels the ER during neurogenesis
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    nature.com/articles/s41556-024-01356-4
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527971/
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    A simple method for rapid cloning of complete herpesvirus genomes
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    sciencedirect.com/science/article/pii/S266723752400002X
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD46-targeted theranostics for Positron Emission Tomography and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905524/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904995/
  19. www.sciencedirect.com www.sciencedirect.com
    Ly6C+ monocytes in the skin promote systemic alphavirus dissemination
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    sciencedirect.com/science/article/pii/S2211124724002043
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    Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase
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    sciencedirect.com/science/article/pii/S1074761324000797
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10528807/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Phase I/II trial of HER-2/neu vaccine primed autologous T-cell infusions in patients with treatment refractory HER-2/neu overexpressing breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10754340/
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    sciencedirect.com/science/article/pii/S1535610824000485
  24. Feb 2024
  25. 52.53.155.43 52.53.155.43
    d7-html.html
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    52.53.155.43/285da8d6b2daddbb90f8efe2aa1fe882a90d6c3e/d7-html.html
  26. 52.53.155.43 52.53.155.43
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  29. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  30. 52.53.155.43 52.53.155.43
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  31. aacrjournals.org aacrjournals.org
    Clinical and Immunologic Features of Germline Pathogenic Variant (gPV) Positive Patients with Melanoma
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    aacrjournals.org/clincancerres/article/30/3/564/733552/Clinical-and-Immunologic-Features-of-Germline
  32. aacrjournals.org aacrjournals.org
    Selective DNA-PK inhibition enhances chemotherapy and ionizing radiation activity in soft-tissue sarcomas
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    aacrjournals.org/clincancerres/article/30/3/629/733549/Selective-DNA-PK-Inhibition-Enhances-Chemotherapy
  33. 52.53.155.43 52.53.155.43
    ccr-23-0430-html.html
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts
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    ncbi.nlm.nih.gov/pmc/articles/PMC10922727/
  35. aacrjournals.org aacrjournals.org
    Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts
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    aacrjournals.org/cancerres/article/84/2/211/733118/Erythroid-Differentiation-Enhances-RNA-Mis
  36. 52.53.155.43 52.53.155.43
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    An iron rheostat controls hematopoietic stem cell fate
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    sciencedirect.com/science/article/pii/S1934590924000419
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    Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1
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    sciencedirect.com/science/article/pii/S1567576924002261
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exhausted tumor-infiltrating CD39+CD103+ CD8+ T cells unveil potential for increased survival in human pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875982/
  42. journals.physiology.org journals.physiology.org
    Monocyte immunometabolic reprogramming in human pregnancy: contribution of trophoblast cells
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    journals.physiology.org/doi/full/10.1152/ajpendo.00357.2023
  43. 52.53.155.43 52.53.155.43
    Combined repetitive inhalant endotoxin and collagen-induced arthritis drives inflammatory lung disease and arthritis severity in a testosterone-dependent manner
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    52.53.155.43/d4f6e6a407021b1ce81f693820e55c2451649406/poole-et-al-2024-combined-repetitive-inhalant-endotoxin-and-collagen-induced-arthritis-drive-inflammatory-lung-disease-html.html
  44. www.biorxiv.org www.biorxiv.org
    KDM6A Regulates Immune Response Genes in Multiple Myeloma
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    biorxiv.org/content/10.1101/2024.02.12.579179v1
  45. www.nature.com www.nature.com
    Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies
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    nature.com/articles/s41467-024-45854-3
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    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    sciencedirect.com/science/article/pii/S2211124724001153
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867660/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BCL2 overcomes resistance and augments response to aurora kinase B inhibition by AZD2811 in small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527398/
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    RORα is required for expansion and memory maintenance of ILC1s via a lymph node-liver axis
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    sciencedirect.com/science/article/pii/S2211124724001141
  51. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
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    biorxiv.org/content/10.1101/2023.12.23.573190v1
  52. www.biorxiv.org www.biorxiv.org
    Parkinson's disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neurons in vitro and in vivo
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    biorxiv.org/content/10.1101/2023.12.19.571978v1
  53. www.biorxiv.org www.biorxiv.org
    PINK1 is a target of T cell responses in Parkinson’s disease
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    biorxiv.org/content/10.1101/2024.02.09.579465v1
  54. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
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    embopress.org/doi/10.1038/s44319-024-00077-x
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    Specialized replication mechanisms maintain genome stability at human centromeres
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    sciencedirect.com/science/article/pii/S1097276524000546
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    Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression
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    sciencedirect.com/science/article/pii/S2211124724000822
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    Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D
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    sciencedirect.com/science/article/pii/S2666379124000405
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841667/
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    Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation
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    sciencedirect.com/science/article/pii/S2211124724000743
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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    ncbi.nlm.nih.gov/pmc/articles/PMC10838956/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10839647/
  62. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  63. link.springer.com link.springer.com
    Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes
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    link.springer.com/article/10.1038/s41467-024-44760-y
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    Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina
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    link.springer.com/article/10.1186/s12974-023-02983-8
  65. www.mdpi.com www.mdpi.com
    Therapeutic Delivery of Soluble Fractalkine Ameliorates Vascular Dysfunction in the Diabetic Retina
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    mdpi.com/1422-0067/25/3/1727
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  67. www.biorxiv.org www.biorxiv.org
    Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP
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    biorxiv.org/content/10.1101/2023.09.15.557965v1
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ultrasound-Targeted Microbubble Technology Facilitates SAHH Gene Delivery to Treat Diabetic Cardiomyopathy by Activating AMPK/FOXO3/SIRT3 Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831940/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glioblastoma Extracellular Vesicles Modulate Immune PD-L1 Expression in Accessory Macrophages upon Radiotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831876/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524955/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10525036/
  73. www.nature.com www.nature.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
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    nature.com/articles/s41598-024-52675-3
  74. Jan 2024
  75. www.nature.com www.nature.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
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    nature.com/articles/s41598-024-52675-3
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maresin 1 repletion improves muscle regeneration after volumetric muscle loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10807862/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Metabolism Drives Low-density Lipoprotein-induced Breast Cancer Cell Migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10132314/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  79. www.nature.com www.nature.com
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    nature.com/articles/s41388-024-02947-z
  80. www.sciencedirect.com www.sciencedirect.com
    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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    sciencedirect.com/science/article/pii/S1097276523010717
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794624/
  82. aacrjournals.org aacrjournals.org
    Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts
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    aacrjournals.org/cancerres/article/84/2/211/733118/Erythroid-Differentiation-Enhances-RNA-Mis
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pdgfrβ is required for embryonic specification and confinement of the adult white adipose lineage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10792241/
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    Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation
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    sciencedirect.com/science/article/pii/S266637912300602X
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
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    sciencedirect.com/science/article/pii/S0092867423013430
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    Inherited blood cancer predisposition through altered transcription elongation
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    sciencedirect.com/science/article/pii/S009286742301348X
  88. www.sciencedirect.com www.sciencedirect.com
    Human uterine natural killer cells regulate differentiation of extravillous trophoblast early in pregnancy
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