1,264 Matching Annotations
  1. Nov 2018
  2. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
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    sciencedirect.com/science/article/pii/S1535610817305159
  3. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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    sciencedirect.com/science/article/pii/S153561081730555X
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    Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis
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    sciencedirect.com/science/article/pii/S1550413117307155
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    IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure
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    sciencedirect.com/science/article/pii/S0092867417313661
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    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
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    sciencedirect.com/science/article/pii/S0092867417315003
  7. europepmc.org europepmc.org
    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.
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    europepmc.org/articles/PMC5608509/
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    Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
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    sciencedirect.com/science/article/pii/S2451945617303549
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    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
  10. academic.oup.com academic.oup.com
    The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor
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    academic.oup.com/endo/article/159/2/945/4675087
  11. academic.oup.com academic.oup.com
    Insulinlike Growth Factor–Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance
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    academic.oup.com/endo/article/159/2/696/4657266
  12. academic.oup.com academic.oup.com
    Direct Activation of Angiotensin II Type 2 Receptors Enhances Muscle Microvascular Perfusion, Oxygenation, and Insulin Delivery in Male Rats
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    academic.oup.com/endo/article/159/2/685/4657267
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    Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S1534580717307359
  14. academic.oup.com academic.oup.com
    Untitled document
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    academic.oup.com/endo/article/159/1/184/4605126
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    Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes
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    sciencedirect.com/science/article/pii/S1934590917303211
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    Untitled document
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    academic.oup.com/endo/article/159/1/285/4259053
  17. europepmc.org europepmc.org
    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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    europepmc.org/articles/PMC5734934/
  18. www.sciencedirect.com www.sciencedirect.com
    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1534580717308717
  19. academic.oup.com academic.oup.com
    Region-Specific Suppression of Hypothalamic Responses to Insulin To Adapt to Elevated Maternal Insulin Secretion During Pregnancy
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    academic.oup.com/endo/article/158/12/4257/4283042
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    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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    sciencedirect.com/science/article/pii/S1097276517307025
  21. Nov 2017
  22. academic.oup.com academic.oup.com
    Hydrogen Sulfide and Sulfate Prebiotic Stimulates the Secretion of GLP-1 and Improves Glycemia in Male Mice
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    academic.oup.com/endo/article/158/10/3416/4058080/Hydrogen-Sulfide-and-Sulfate-Prebiotic-Stimulates
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    Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity
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    sciencedirect.com/science/article/pii/S2451945617303136
  24. www.sciencedirect.com www.sciencedirect.com
    The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells
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    sciencedirect.com/science/article/pii/S1074761317303692
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    A Split-Abl Kinase for Direct Activation in Cells
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    sciencedirect.com/science/article/pii/S2451945617302817
  26. www.jneurosci.org www.jneurosci.org
    PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network
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    jneurosci.org/content/37/36/8595
  27. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
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    sciencedirect.com/science/article/pii/S1534580717306305
  28. elifesciences.org elifesciences.org
    Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity
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    elifesciences.org/articles/28527
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagy impairment by caspase‐1‐dependent inflammation mediates memory loss in response to β‐Amyloid peptide accumulation
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24130/full
  30. www.sciencedirect.com www.sciencedirect.com
    Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye
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    sciencedirect.com/science/article/pii/S1534580717305968
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    Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14081/full
  32. academic.oup.com academic.oup.com
    Effects of the Activation of Three Major Hepatic Akt Substrates on Glucose Metabolism in Male Mice
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    academic.oup.com/endo/article/158/8/2659/3814633/Effects-of-the-Activation-of-Three-Major-Hepatic
  33. academic.oup.com academic.oup.com
    Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis
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    academic.oup.com/endo/article/158/8/2503/3861370/Protective-Role-of-Complement-C3-Against-Cytokine
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    A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding
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    sciencedirect.com/science/article/pii/S1550413117304345
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    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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    sciencedirect.com/science/article/pii/S1097276517304914
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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    sciencedirect.com/science/article/pii/S1074761317302339
  37. academic.oup.com academic.oup.com
    EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis
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    academic.oup.com/jes/article/1/2/127/2930778/EGFR-Induces-E2F1-Mediated-Corticotroph
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    IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis
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    sciencedirect.com/science/article/pii/S155041311730342X
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    IGF1R Expression in Ovarian Granulosa Cells is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice
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    academic.oup.com/endo/article/158/7/2309/3605334/IGF1R-Expression-in-Ovarian-Granulosa-Cells-Is
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    Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival
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    sciencedirect.com/science/article/pii/S1097276517302356
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    Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis
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    sciencedirect.com/science/article/pii/S109727651730237X
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    mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
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    sciencedirect.com/science/article/pii/S1097276517303945
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    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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    sciencedirect.com/science/article/pii/S1535610817302027
  44. elifesciences.org elifesciences.org
    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
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    elifesciences.org/articles/26362
  45. academic.oup.com academic.oup.com
    JMJD3 Is Crucial for the Female AVPV RIP-Cre Neuron-Controlled Kisspeptin–Estrogen Feedback Loop and Reproductive Function
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    academic.oup.com/endo/article/158/6/1798/3064423/JMJD3-Is-Crucial-for-the-Female-AVPV-RIP-Cre
  46. academic.oup.com academic.oup.com
    Hyperhomocysteinemia Promotes Insulin Resistance and Adipose Tissue Inflammation in PCOS Mice Through Modulating M2 Macrophage Polarization via Estrogen Suppression
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    academic.oup.com/endo/article/158/5/1181/3070535/Hyperhomocysteinemia-Promotes-Insulin-Resistance
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14033/full
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    Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats
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    link.springer.com/article/10.1007/s12035-017-0538-y
  49. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    elifesciences.org/content/6/e22871
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    The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover
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    sciencedirect.com/science/article/pii/S0092867417304154
  51. elifesciences.org elifesciences.org
    SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
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    elifesciences.org/content/6/e25158
  52. www.sciencedirect.com www.sciencedirect.com
    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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    sciencedirect.com/science/article/pii/S2451945617300636
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    Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes
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    sciencedirect.com/science/article/pii/S0092867417302490
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    Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
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    sciencedirect.com/science/article/pii/S193459091630399X
  55. www.jneurosci.org www.jneurosci.org
    Soluble cpg15 from Astrocytes Ameliorates Neurite Outgrowth Recovery of Hippocampal Neurons after Mouse Cerebral Ischemia
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    jneurosci.org/content/37/6/1628.long
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    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
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    sciencedirect.com/science/article/pii/S1097276517300539
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    Multivalent Small-Molecule Pan-RAS Inhibitors
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    sciencedirect.com/science/article/pii/S0092867417301848
  58. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis
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    sciencedirect.com/science/article/pii/S1534580717300072
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
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    ncbi.nlm.nih.gov/pmc/articles/PMC4931344/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC5241115/
  61. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    elifesciences.org/content/5/e17047