2,250 Matching Annotations
  1. Sep 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
    1
    1. scibot 07 Sep 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2023.107505

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    ncbi.nlm.nih.gov/pmc/articles/PMC10470315/
  3. www.sciencedirect.com www.sciencedirect.com
    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113070

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    sciencedirect.com/science/article/pii/S2211124723010811
  4. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner
    1
    1. scibot 06 Sep 2023
      RRID:Addgene_12260

      DOI: 10.1096/fj.202202145RRR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202145RRR
  5. Aug 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
    1
    1. scibot 31 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1186/s12967-023-04448-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  7. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
    1
    1. scibot 30 Aug 2023
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      DOI: 10.1016/j.xgen.2023.100399

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    sciencedirect.com/science/article/pii/S2666979X23002136
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
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    1. scibot 26 Aug 2023
      Addgene #12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC10437005/
  9. www.sciencedirect.com www.sciencedirect.com
    4-Octyl itaconate restricts STING activation by blocking its palmitoylation
    1
    1. scibot 25 Aug 2023
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    sciencedirect.com/science/article/pii/S2211124723010513
  10. www.nature.com www.nature.com
    Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
    1
    1. scibot 24 Aug 2023
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      DOI: 10.1038/s41467-023-40222-z

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    nature.com/articles/s41467-023-40222-z
  11. www.nature.com www.nature.com
    An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver
    1
    1. scibot 24 Aug 2023
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    nature.com/articles/s41467-023-40688-x
  12. www.nature.com www.nature.com
    TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
    1
    1. scibot 24 Aug 2023
      plasmid_12260

      DOI: 10.1038/s41467-023-40755-3

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    nature.com/articles/s41467-023-40755-3
  13. link.springer.com link.springer.com
    Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor
    1
    1. scibot 23 Aug 2023
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    link.springer.com/article/10.1186/s12977-023-00629-4
  14. 52.53.155.43 52.53.155.43
    Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses
    3
    1. scibot 19 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2023.112925

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    2. scibot 12 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2023.112925

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    3. scibot 10 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2023.112925

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    52.53.155.43/4c45d6c83e1bf2a7bb63a95a964192d48e86ccfd/PIIS2211124723009361-html.html
  15. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      Plasmid_12260

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      Plasmid_12260

      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  16. www.biorxiv.org www.biorxiv.org
    Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
    1
    1. scibot 18 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.08.08.552533

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    biorxiv.org/content/10.1101/2023.08.08.552533v1
  17. www.nature.com www.nature.com
    Pharmacological perturbation of the phase-separating protein SMNDC1
    1
    1. scibot 17 Aug 2023
      plasmid_12260

      DOI: 10.1038/s41467-023-40124-0

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    nature.com/articles/s41467-023-40124-0
  18. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
    2
    1. scibot 17 Aug 2023
      plasmid_12260

      DOI: 10.1016/j.celrep.2023.112961

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    2. scibot 10 Aug 2023
      plasmid_12260

      DOI: 10.1016/j.celrep.2023.112961

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    52.53.155.43/e4339d2342058d0ba733e06b854674a1d2f752a1/PIIS2211124723009725-html.html
  19. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
    2
    1. scibot 17 Aug 2023
      plasmid_12260

      DOI: 10.1016/j.celrep.2023.112944

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    2. scibot 11 Aug 2023
      plasmid_12260

      DOI: 10.1016/j.celrep.2023.112944

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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  20. 52.53.155.43 52.53.155.43
    2023.08.10.552871v1.full-html.html
    1
    1. scibot 17 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.08.10.552871

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    52.53.155.43/9a921f486a63ee1a20d0dca87aaaa0ac2df996bc/2023.08.10.552871v1.full-html.html
  21. 52.53.155.43 52.53.155.43
    2023.08.14.553170v1.full-html.html
    1
    1. scibot 17 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.08.14.553170

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    52.53.155.43/d7a2d366bab3ad37074f4f2d77760529b19b5477/2023.08.14.553170v1.full-html.html
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing
    1
    1. scibot 16 Aug 2023
      RRID: Addgene_12260

      DOI: 10.1063/5.0156628

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    ncbi.nlm.nih.gov/pmc/articles/PMC10423075/
  23. www.sciencedirect.com www.sciencedirect.com
    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101144

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    sciencedirect.com/science/article/pii/S2666379123002975
  24. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 16 Aug 2023
      plasmid_12260

      DOI: 10.1101/2023.07.26.550648

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.isci.2023.107368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder
    1
    1. scibot 09 Aug 2023
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      DOI: 10.1016/j.isci.2023.107300

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405067/
  27. 52.53.155.43 52.53.155.43
    mcr-22-0916-html.html
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    1. scibot 09 Aug 2023
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      DOI: 10.1158/1541-7786.MCR-22-0916

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    52.53.155.43/ee24162242ef05486fd8a6e1481e2011af4e24fe/mcr-22-0916-html.html
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer
    1
    1. scibot 05 Aug 2023
      RRID:Addgene_12260

      DOI: 10.1158/2326-6066.CIR-22-0644

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    ncbi.nlm.nih.gov/pmc/articles/PMC10398359/
  29. www.sciencedirect.com www.sciencedirect.com
    Mapping the dynamic high-density lipoprotein synapse
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    1. scibot 03 Aug 2023
      addgene:12260

      DOI: 10.1016/j.atherosclerosis.2023.117200

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      DOI: 10.1016/j.atherosclerosis.2023.117200

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    sciencedirect.com/science/article/pii/S0021915023051079
  30. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    1. scibot 03 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112927

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    sciencedirect.com/science/article/pii/S2211124723009385
  31. www.embopress.org www.embopress.org
    The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma
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    1. scibot 03 Aug 2023
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      DOI: 10.15252/embr.202153408

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    embopress.org/doi/10.15252/embr.202153408
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
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      DOI: 10.1101/2023.07.14.549074

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    ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
  33. Jul 2023
  34. www.nature.com www.nature.com
    Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
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      DOI: 10.1038/s41594-023-01041-4

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    nature.com/articles/s41594-023-01041-4
  35. www.sciencedirect.com www.sciencedirect.com
    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
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    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.immuni.2023.07.002

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    sciencedirect.com/science/article/pii/S107476132300314X
  36. www.embopress.org www.embopress.org
    Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
    1
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      DOI: 10.15252/embr.202256279

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    embopress.org/doi/10.15252/embr.202256279
  37. www.sciencedirect.com www.sciencedirect.com
    Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy
    1
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    sciencedirect.com/science/article/pii/S221112472300863X
  38. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.020

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    sciencedirect.com/science/article/pii/S0092867423006967
  39. www.biorxiv.org www.biorxiv.org
    Deep mutational scanning of whole SARS-CoV-2 spike in an inverted infection system
    1
    1. scibot 25 Jul 2023
      addgene_12260

      DOI: 10.1101/2023.07.17.549430

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    biorxiv.org/content/10.1101/2023.07.17.549430v1
  40. www.sciencedirect.com www.sciencedirect.com
    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112819

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    sciencedirect.com/science/article/pii/S2211124723008306
  41. www.sciencedirect.com www.sciencedirect.com
    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
    1
    1. scibot 21 Jul 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2023.112794

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    sciencedirect.com/science/article/pii/S2211124723008057
  42. 52.53.155.43 52.53.155.43
    Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal
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      12260

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  43. www.biorxiv.org www.biorxiv.org
    Neuronal Activation of the Gαq Protein EGL-30/GNAQ Late in Life Rejuvenates Cognition Across Species
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    1. scibot 13 Jul 2023
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      DOI: 10.1101/2023.06.06.543909

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  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer
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      RRID:Addgene_12

      DOI: 10.1002/advs.202301088

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin nucleators safeguard replication forks by limiting nascent strand degradation
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      Addgene_12260

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic profiling of medulloblastoma surfaceome
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      RRID:Addgene_12260

      DOI: 10.1186/s40478-023-01609-7

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  47. www.sciencedirect.com www.sciencedirect.com
    Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
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      Addgene_12260

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  48. 52.53.155.43 52.53.155.43
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    1. scibot 08 Jul 2023
      Addgene, 12260

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  49. www.nature.com www.nature.com
    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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    1. scibot 08 Jul 2023
      RRID:Addgene_12260

      DOI: 10.1038/s41420-023-01526-7

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  50. www.sciencedirect.com www.sciencedirect.com
    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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      RRID:Addgene_12260

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  51. 52.53.155.43 52.53.155.43
    qiad076-html.html
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    1. scibot 07 Jul 2023
      plasmid_12260

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  52. www.sciencedirect.com www.sciencedirect.com
    The anti-SARS-CoV-2 effect and mechanism of Chiehyuan herbal oral protection solution
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    1. scibot 06 Jul 2023
      RRID:Addgene_12260

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  53. www.sciencedirect.com www.sciencedirect.com
    Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways
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      RRID:Addgene_12260

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  54. 52.53.155.43 52.53.155.43
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    2
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  55. Jun 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
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  57. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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  58. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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  59. www.sciencedirect.com www.sciencedirect.com
    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes
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    1. scibot 24 Jun 2023
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  61. link.springer.com link.springer.com
    Development of a Series of Neutralizing Nanobodies against SARS-CoV-2 Spike Protein
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      DOI: 10.1134/S0026893323030196

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  62. www.mdpi.com www.mdpi.com
    Effects of the Co-Overexpression of the BCL and BDNF Genes on the Gamma-Aminobutyric Acid-Ergic Differentiation of Wharton’s-Jelly-Derived Mesenchymal Stem Cells
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    1. scibot 23 Jun 2023
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      DOI: 10.3390/biomedicines11061751

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  63. www.sciencedirect.com www.sciencedirect.com
    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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    1. scibot 23 Jun 2023
      Plasmid_12260

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  64. www.embopress.org www.embopress.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
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    1. scibot 23 Jun 2023
      RRID:Addgene_12260

      DOI: 10.15252/embr.202256399

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  65. www.sciencedirect.com www.sciencedirect.com
    Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression
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      Plasmid_12260

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      RRID:Addgene_12260s

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  66. www.sciencedirect.com www.sciencedirect.com
    LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.devcel.2023.05.009

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    sciencedirect.com/science/article/pii/S1534580723002423
  67. www.sciencedirect.com www.sciencedirect.com
    Adhesion tunes speed and persistence by coordinating protrusions and extracellular matrix remodeling
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronutrient optimization for tissue engineered articular cartilage production of type II collagen
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      DOI: 10.3389/fbioe.2023.1179332

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
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      DOI: 10.1158/2767-9764.CRC-23-0030

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  70. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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    1. scibot 22 Jun 2023
      plasmid_12260

      DOI: 10.1101/2023.06.14.544493

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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  71. www.biorxiv.org www.biorxiv.org
    Host ZCCHC3 blocks HIV-1 infection and production by a dual mechanism
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      RRID:Addgene_12260

      DOI: 10.1101/2023.06.14.544911

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    biorxiv.org/content/10.1101/2023.06.14.544911v2
  72. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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  73. www.sciencedirect.com www.sciencedirect.com
    MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
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    1. scibot 21 Jun 2023
      Addgene_12260

      DOI: 10.1016/j.ccell.2023.05.015

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    LRP12 is an endogenous transmembrane inactivator of α4 integrins
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112667

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  75. www.sciencedirect.com www.sciencedirect.com
    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
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      plasmid_12260

      DOI: 10.1016/j.molcel.2023.05.018

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  76. www.sciencedirect.com www.sciencedirect.com
    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2023.05.026

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  77. www.nature.com www.nature.com
    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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      DOI: 10.1038/s41388-023-02742-2

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  78. aacrjournals.org aacrjournals.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
    1
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      DOI: 10.1158/2326-6066.CIR-22-0374

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    aacrjournals.org/cancerimmunolres/article/11/6/830/726521/EBV-Upregulated-B7-H3-Inhibits-NK-cell-Mediated
  79. aacrjournals.org aacrjournals.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
    1
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      DOI: 10.1158/1541-7786.MCR-22-0554

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    aacrjournals.org/mcr/article/21/5/444/726027/MYC-Glutamine-Dependency-Is-a-Therapeutic
  80. aacrjournals.org aacrjournals.org
    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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      DOI: 10.1158/1541-7786.MCR-22-0552

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    aacrjournals.org/mcr/article/21/6/578/726510/USP10-Regulates-ZEB1-Ubiquitination-and-Protein
  81. www.embopress.org www.embopress.org
    STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory
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    embopress.org/doi/10.15252/embj.2022112259
  82. aacrjournals.org aacrjournals.org
    ASPM activates Hedgehog and Wnt signaling to promote small cell lung cancer stemness and progression
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      RRID: Addgene_12260

      DOI: 10.1158/0008-5472.CAN-22-2496

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    aacrjournals.org/cancerres/article/83/6/830/718576/ASPM-Activates-Hedgehog-and-Wnt-Signaling-to
  83. aacrjournals.org aacrjournals.org
    AMPK phosphorylates ZDHHC13 to increase MC1R activity and suppress melanomagenesis
    1
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      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-22-2595

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  84. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo
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  86. www.sciencedirect.com www.sciencedirect.com
    KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
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  87. May 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screening
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  89. www.sciencedirect.com www.sciencedirect.com
    Proteomics of immune cells from liver tumors reveals immunotherapy targets
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy
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    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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  92. www.biorxiv.org www.biorxiv.org
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation and proteomic profiles in Burkitt lymphoma
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    Unraveling human, rodent and snake Kolmioviridae replication to anticipate cross-species transmission
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    A gene silencing pipeline to interrogate human cDC1 and pDC development and functions
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    Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells
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    Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia
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    The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis
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    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    Modeling human ectopic pregnancies with trophoblast and vascular organoids
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  101. elifesciences.org elifesciences.org
    Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction
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  102. www.biorxiv.org www.biorxiv.org
    Mechanisms controlling membrane recruitment and activation of autoinhibited SHIP1
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    Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells
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  105. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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  107. www.nature.com www.nature.com
    A prime editor mouse to model a broad spectrum of somatic mutations in vivo
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  108. journals.plos.org journals.plos.org
    XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis
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    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized metrics for orthogonal combinatorial CRISPR screens
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  112. www.nature.com www.nature.com
    Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD-associated enhancers shape human cardiomyocyte lineage commitment
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  115. www.sciencedirect.com www.sciencedirect.com
    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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  116. www.sciencedirect.com www.sciencedirect.com
    Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
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    A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
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  118. journals.asm.org journals.asm.org
    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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  120. www.biorxiv.org www.biorxiv.org
    Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly
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  121. Apr 2023
  122. www.sciencedirect.com www.sciencedirect.com
    Integrative dissection of gene regulatory elements at base resolution
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  123. www.sciencedirect.com www.sciencedirect.com
    Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis
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  124. www.biorxiv.org www.biorxiv.org
    Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
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  125. www.sciencedirect.com www.sciencedirect.com
    A tissue injury sensing and repair pathway distinct from host pathogen defense
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  126. www.sciencedirect.com www.sciencedirect.com
    C9ORF72 suppresses JAK-STAT mediated inflammation
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  127. aacrjournals.org aacrjournals.org
    Dual mTORC1/2 inhibition synergistically enhances AML cell death in combination with the BCL2 antagonist venetoclax
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  128. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
    1
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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  129. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer
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  130. www.sciencedirect.com www.sciencedirect.com
    Identifying constitutive and context-specific molecular-tension-sensitive protein recruitment within focal adhesions
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    sciencedirect.com/science/article/pii/S1534580723000746
  131. www.biorxiv.org www.biorxiv.org
    Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons
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  132. www.sciencedirect.com www.sciencedirect.com
    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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  133. link.springer.com link.springer.com
    CD95/Fas ligand mRNA is toxic to cells through more than one mechanism
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  134. www.sciencedirect.com www.sciencedirect.com
    PHLPP1 regulates PINK1-parkin signalling and life span
    2
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-suppressor scanning for systematic discovery of drug resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073897/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10054921/
  137. www.nature.com www.nature.com
    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
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    nature.com/articles/s41467-023-37454-4
  138. reader.elsevier.com reader.elsevier.com
    Phosphorylation barcodes direct biased chemokine signaling at CXCR3
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer’s disease
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  140. www.sciencedirect.com www.sciencedirect.com
    Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
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    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
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  142. www.sciencedirect.com www.sciencedirect.com
    Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens
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  143. 52.53.155.43 52.53.155.43
    A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma
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    52.53.155.43/50807bad4ac98194c420b81c9bc8a62408d03259/Molecular Oncology - 2023 - Montemagno - A group of novel VEGF splice variants as alternative therapeutic targets in renal-html.html
  144. www.biorxiv.org www.biorxiv.org
    Overexpression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo
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    Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities
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    ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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  148. www.biorxiv.org www.biorxiv.org
    Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation
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  150. Mar 2023
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
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  152. www.biorxiv.org www.biorxiv.org
    Alternative splicing of its 5’ untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
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    biorxiv.org/content/10.1101/2023.02.19.529123v2
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    Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
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  155. www.sciencedirect.com www.sciencedirect.com
    A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro
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    Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells
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    Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development
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  158. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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  159. academic.oup.com academic.oup.com
    Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells
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  161. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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  162. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
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  163. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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  164. www.biorxiv.org www.biorxiv.org
    Disease Modifying Osteoarthritis Drug Discovery Using A Temporal Phenotypic Reporter In Primary Human Chondrocytes
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  165. www.mdpi.com www.mdpi.com
    MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors’ Efficacy in Neuroblastoma Cells
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  166. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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  168. www.sciencedirect.com www.sciencedirect.com
    FAM193A is a positive regulator of p53 activity
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    Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB
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    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.chembiol.2023.02.008

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    sciencedirect.com/science/article/pii/S2451945623000570
  170. www.mdpi.com www.mdpi.com
    Inhibition of RNA Polymerase III Augments the Anti-Cancer Properties of TNFα
    1
    1. scibot 09 Mar 2023
      RRID:Addgene_12260

      DOI: 10.3390/cancers15051495

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    mdpi.com/2072-6694/15/5/1495
  171. www.sciencedirect.com www.sciencedirect.com
    IFNγ is a central node of cancer immune equilibrium
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    1. scibot 09 Mar 2023
      Addgene_12260

      DOI: 10.1016/j.celrep.2023.112219

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    sciencedirect.com/science/article/pii/S2211124723002309
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer
    2
    1. scibot 05 Mar 2023
      Addgene_12260

      DOI: 10.1158/0008-5472.CAN-21-3713

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      RRID:Addgene_122

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444950/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
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    1. scibot 05 Mar 2023
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-21-2908

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444958/
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
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    1. scibot 04 Mar 2023
      plasmid_12260

      DOI: 10.1016/j.xcrm.2023.100937

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    ncbi.nlm.nih.gov/pmc/articles/PMC9975292/
  175. www.sciencedirect.com www.sciencedirect.com
    DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
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    1. scibot 03 Mar 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2023.02.009

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    sciencedirect.com/science/article/pii/S1097276523001077
  176. www.biorxiv.org www.biorxiv.org
    LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes
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    1. scibot 03 Mar 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.01.31.526513

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    biorxiv.org/content/10.1101/2023.01.31.526513v1
  177. www.biorxiv.org www.biorxiv.org
    SYNGAP1 deficiency disrupts neoteny in human cortical neurons in vivo
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    1. scibot 03 Mar 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.01.14.524054

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    biorxiv.org/content/10.1101/2023.01.14.524054v1
  178. www.mdpi.com www.mdpi.com
    Inactivation of SARS-CoV-2 on Surfaces by Cold-Plasma-Generated Reactive Species
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    1. scibot 02 Mar 2023
      RRID:Addgene_12260

      DOI: 10.3390/bioengineering10030280

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    mdpi.com/2306-5354/10/3/280
  179. www.biorxiv.org www.biorxiv.org
    Mapping the dynamic cell surface interactome of high-density lipoprotein reveals Aminopeptidase N as modulator of its endothelial uptake
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    1. scibot 02 Mar 2023
      RRID:Addgene_12260

      DOI: 10.1101/2023.01.03.522574

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    biorxiv.org/content/10.1101/2023.01.03.522574v1
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies
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    1. scibot 02 Mar 2023
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      DOI: 10.3390/vaccines11020313

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    ncbi.nlm.nih.gov/pmc/articles/PMC9962293/
  181. Feb 2023
  182. www.sciencedirect.com www.sciencedirect.com
    PIMT regulates Hepatic Gluconeogenesis in Mice
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    1. scibot 25 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2023.106120

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    sciencedirect.com/science/article/pii/S2589004223001979
  183. www.sciencedirect.com www.sciencedirect.com
    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
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    1. scibot 24 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2023.112134

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    sciencedirect.com/science/article/pii/S2211124723001456
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HER2-driven breast cancer suppression by the JNK signaling pathway
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    1. scibot 24 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1073/pnas.2218373120

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942916/
  185. www.sciencedirect.com www.sciencedirect.com
    E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
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    1. scibot 23 Feb 2023
      Plasmid_12260

      DOI: 10.1016/j.molcel.2023.01.019

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    sciencedirect.com/science/article/pii/S1097276523000424
  186. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
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    1. scibot 23 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.xcrm.2023.100941

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    sciencedirect.com/science/article/pii/S2666379123000332
  187. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    1. scibot 23 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.cmet.2023.01.011

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    sciencedirect.com/science/article/pii/S1550413123000116
  188. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8+ T Cells
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    1. scibot 23 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1002/advs.202207499

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    onlinelibrary.wiley.com/doi/10.1002/advs.202207499
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma
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    1. scibot 17 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-21-4313

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    ncbi.nlm.nih.gov/pmc/articles/PMC9388591/
  190. journals.lww.com journals.lww.com
    HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes
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    1. scibot 17 Feb 2023
      plasmid_12260

      DOI: 10.1681/ASN.2022010076

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    journals.lww.com/jasn/Fulltext/9900/HNF1B_Alters_an_Evolutionarily_Conserved.41.aspx
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs
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    1. scibot 15 Feb 2023
      Addgene_12260

      DOI: 10.1371/journal.pbio.3001967

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
  192. www.sciencedirect.com www.sciencedirect.com
    CRISPR-based large-scale modeling of loss-of-function mutations to investigate mechanisms of stress resistance in cancer
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    1. scibot 15 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2023.102097

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    sciencedirect.com/science/article/pii/S2666166723000552
  193. www.nature.com www.nature.com
    ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions
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    1. scibot 11 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1038/s12276-023-00945-x

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    nature.com/articles/s12276-023-00945-x
  194. www.sciencedirect.com www.sciencedirect.com
    Monitoring cell fate in 3D organotypic human squamous epithelial cultures
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    1. scibot 09 Feb 2023
      Addgene_12260

      DOI: 10.1016/j.xpro.2023.102101

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    sciencedirect.com/science/article/pii/S266616672300059X
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression
    1
    1. scibot 09 Feb 2023
      RRID:Addgene_12260

      DOI: 10.1158/1541-7786.MCR-22-0111

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357060/