2,607 Matching Annotations
  1. Nov 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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    ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
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    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
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    Nna1, Essential for Purkinje Cell Survival, Is also Associated with Emotion and Memory
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    ncbi.nlm.nih.gov/pmc/articles/PMC9654422/
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    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
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    Identification of regenerating island-derived protein 3E in dogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9650133/
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    The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9655849/
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    Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies
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    sciencedirect.com/science/article/pii/S1550413122004909
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    Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide
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    CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
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    SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice
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    frontiersin.org/articles/10.3389/fphys.2022.992679/full
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    Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer
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    Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia
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    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633742/
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    Shared and unique phosphoproteomics responses in skeletal muscle from exercise models and in hyperammonemic myotubes
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    Foxe1 Deletion in the Adult Mouse is Associated with Increased Thyroidal Mast Cells and Hypothyroidism
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    Isoflurane has no effect on cognitive or behavioral performance in a mouse model of early-stage Alzheimer’s disease
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    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
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    Intestinal Apc-inactivation induces HSP25 dependency
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    embopress.org/doi/10.15252/emmm.202216194
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    NetrinG1+ cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
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    Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis
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    science.org/doi/10.1126/sciimmunol.abm9811
  26. Oct 2022
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    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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    sciencedirect.com/science/article/pii/S0092867422012521
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
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    A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation
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    sciencedirect.com/science/article/pii/S2211124722013985
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    The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9519039/
  31. journals.physiology.org journals.physiology.org
    Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes
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    journals.physiology.org/doi/10.1152/ajpcell.00341.2022
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    Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD36
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    sciencedirect.com/science/article/pii/S0024320522008165
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    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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    sciencedirect.com/science/article/pii/S1097276522009558
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    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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    The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity
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    science.org/doi/10.1126/sciadv.abo5578
  36. elifesciences.org elifesciences.org
    N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia
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    elifesciences.org/articles/74031
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    Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression
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    sciencedirect.com/science/article/pii/S0304383522004475
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth
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    Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection
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    Necroptosis plays a crucial role in the exacerbation of... : Neural Regeneration Research
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  41. Sep 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Hepatic ER stress suppresses adipose browning through ATF4-CIRP-ANGPTL3 cascade
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    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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    Modulation of Specific Sphingosine-1-Phosphate Receptors Augments a Repair Mediating Schwann Cell Phenotype
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    ncbi.nlm.nih.gov/pmc/articles/PMC9499684/
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    Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9495704/
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    Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury
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    sciencedirect.com/science/article/pii/S2352396422004571
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    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
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    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
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    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
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    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2211124722011287
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    Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects
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    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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    Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels
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    Target protein localization and its impact on PROTAC-mediated degradation
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    ncbi.nlm.nih.gov/pmc/articles/PMC9442361/
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    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
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    Methionine metabolism controls the B cell EBV epigenome and viral latency
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    Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy
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    Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
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  61. Aug 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    PH domain-mediated autoinhibition and oncogenic activation of Akt
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    Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma
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    Small extracellular vesicles secreted by induced... : Neural Regeneration Research
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    Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9405998/
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    Knockout of Sirt2 alleviates traumatic brain injury in mice
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    The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation
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    Visual-area-specific tonic modulation of GABA release by endocannabinoids sets the activity and coordination of neocortical principal neurons
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    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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    Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements
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    Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches
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    SARS-CoV-2 Spike N-Terminal Domain modulates TMPRSS2-dependent viral entry and fusogenicity
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    Herpesvirus-induced spermidine synthesis and eIF5A hypusination for viral episomal maintenance
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    STK25 inhibits PKA signaling by phosphorylating PRKAR1A
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    Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis
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    Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation
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    Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints
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    link.springer.com/article/10.1007/s12035-022-02980-7
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    Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
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    Cardiac fibroblast heat shock protein 47 aggravates cardiac fibrosis post myocardial ischemia–reperfusion injury by encouraging ubiquitin specific peptidase 10 dependent Smad4 deubiquitination
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    Combination of type I and type II MET tyrosine kinase inhibitors as therapeutic approach to prevent resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828669/
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    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8831451/
  86. Jul 2022
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
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    Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
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    ncbi.nlm.nih.gov/pmc/articles/PMC9319455/
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  90. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
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