2,154 Matching Annotations
  1. Dec 2022
  2. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    1
    1. scibot 08 Dec 2022
      plasmid_12259

      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  3. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
    1
    1. scibot 03 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1158/2159-8290.CD-22-0287

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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  4. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    1
    1. scibot 02 Dec 2022
      RRID:Addgene_12259

      DOI: 10.15252/emmm.202115631

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    embopress.org/doi/10.15252/emmm.202115631
  5. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016059
  6. www.sciencedirect.com www.sciencedirect.com
    BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
    1
    1. scibot 01 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016060
  7. Nov 2022
  8. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
    1
    1. scibot 24 Nov 2022
      Addgene_12259

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    sciencedirect.com/science/article/pii/S2211124722015492
  9. www.sciencedirect.com www.sciencedirect.com
    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
    1
    1. scibot 24 Nov 2022
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    sciencedirect.com/science/article/pii/S2211124722015522
  10. 52.53.155.43 52.53.155.43
    Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis
    1
    1. scibot 22 Nov 2022
      plasmid_12259

      DOI: 10.1093/hmg/ddac235

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    52.53.155.43/cc79e40c92dade70c5729b9199717becabfd0bfe/ddac235-html.html
  11. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
    1
    1. scibot 22 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1158/1078-0432.CCR-22-1357

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    aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
    1
    1. scibot 19 Nov 2022
      RRID:Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC9668739/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
    1
    1. scibot 18 Nov 2022
      RRID: Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  14. www.pnas.org www.pnas.org
    Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
    1
    1. scibot 17 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1073/pnas.2122188119

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    pnas.org/doi/abs/10.1073/pnas.2122188119
  15. www.sciencedirect.com www.sciencedirect.com
    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
    1
    1. scibot 16 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2022.111645

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    sciencedirect.com/science/article/pii/S2211124722015169
  16. www.sciencedirect.com www.sciencedirect.com
    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
    1
    1. scibot 16 Nov 2022
      12259

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    sciencedirect.com/science/article/pii/S2666379122003809
  17. academic.oup.com academic.oup.com
    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
    1
    1. scibot 15 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1093/brain/awac325

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    academic.oup.com/brain/advance-article/doi/10.1093/brain/awac325/6694190
  18. www.sciencedirect.com www.sciencedirect.com
    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
    1
    1. scibot 11 Nov 2022
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1535610822005001
  19. www.sciencedirect.com www.sciencedirect.com
    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
    1
    1. scibot 10 Nov 2022
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    sciencedirect.com/science/article/pii/S2211124722014632
  20. www.sciencedirect.com www.sciencedirect.com
    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
    1
    1. scibot 09 Nov 2022
      Plasmid_12259

      DOI: 10.1016/j.chembiol.2022.10.003

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    sciencedirect.com/science/article/pii/S2451945622003579
  21. www.sciencedirect.com www.sciencedirect.com
    The phenotypic landscape of essential human genes
    1
    1. scibot 08 Nov 2022
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      DOI: 10.1016/j.cell.2022.10.017

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    sciencedirect.com/science/article/pii/S0092867422013599
  22. www.sciencedirect.com www.sciencedirect.com
    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
    1
    1. scibot 05 Nov 2022
      RRID: Addgene_12259

      DOI: 10.1016/j.celrep.2022.111482

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    sciencedirect.com/science/article/pii/S2211124722013328
  23. www.sciencedirect.com www.sciencedirect.com
    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
    1
    1. scibot 04 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.ccell.2022.10.002

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    sciencedirect.com/science/article/pii/S1535610822004937
  24. www.sciencedirect.com www.sciencedirect.com
    Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
    1
    1. scibot 04 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.xpro.2022.101813

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    sciencedirect.com/science/article/pii/S2666166722006931
  25. www.sciencedirect.com www.sciencedirect.com
    Multiphase coalescence mediates Hippo pathway activation
    1
    1. scibot 03 Nov 2022
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    sciencedirect.com/science/article/pii/S0092867422012557
  26. 52.53.155.43 52.53.155.43
    Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12259

      DOI: 10.21203/rs.3.rs-1913714/v1

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    52.53.155.43/dcaead73d85858fbd3a58018d7559608353495d7/7c83488d-0d7f-4b8a-b1aa-e1329998961d-html.html
  27. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.str.2022.10.003

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    sciencedirect.com/science/article/pii/S0969212622003926
  28. www.nature.com www.nature.com
    HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
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    1. scibot 03 Nov 2022
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      DOI: 10.1038/s41467-022-34252-2

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    nature.com/articles/s41467-022-34252-2
  29. www.nature.com www.nature.com
    HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
    1
    1. scibot 02 Nov 2022
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      DOI: 10.1038/s41598-022-21714-2

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    nature.com/articles/s41598-022-21714-2
  30. Oct 2022
  31. 52.53.155.43 52.53.155.43
    ccr-22-1357-html.html
    1
    1. scibot 27 Oct 2022
      RRID:Addgene_12259

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    52.53.155.43/b06e31323fa05ae99a3ee4406ee4cfeac8533d8b/ccr-22-1357-html.html
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral vector mediated gene therapy for type I Dent disease effectively ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice
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    1. scibot 27 Oct 2022
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      DOI: 10.1016/j.omtm.2022.09.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC9574595/
  33. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Imaging Inflammasome Activation in Microglia
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    1. scibot 27 Oct 2022
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      DOI: 10.1002/cpz1.578

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.578
  34. www.sciencedirect.com www.sciencedirect.com
    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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    sciencedirect.com/science/article/pii/S2211124722014024
  35. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
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    sciencedirect.com/science/article/pii/S221112472201422X
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments
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      DOI: 10.1126/sciadv.abp8416

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    ncbi.nlm.nih.gov/pmc/articles/PMC9524834/
  37. journals.asm.org journals.asm.org
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
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      DOI: 10.1128/mbio.02446-22

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    journals.asm.org/doi/10.1128/mbio.02446-22
  38. www.nature.com www.nature.com
    The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies
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    nature.com/articles/s41467-022-33434-2
  39. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    sciencedirect.com/science/article/pii/S1074761322005088
  40. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
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    sciencedirect.com/science/article/pii/S221112472201364X
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
  42. link.springer.com link.springer.com
    Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector
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    1. scibot 19 Oct 2022
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      DOI: 10.1038/s41598-022-20970-6

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    link.springer.com/article/10.1038/s41598-022-20970-6
  43. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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      DOI: 10.1007/s00018-022-04586-7

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    link.springer.com/article/10.1007/s00018-022-04586-7
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
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      plasmid_12259

      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  45. www.nature.com www.nature.com
    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
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      DOI: 10.1038/s41587-022-01494-w

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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
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    Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing
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    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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    Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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    EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity
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    FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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  90. www.sciencedirect.com www.sciencedirect.com
    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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  91. Jul 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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  93. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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  94. www.sciencedirect.com www.sciencedirect.com
    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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  95. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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  97. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  98. www.sciencedirect.com www.sciencedirect.com
    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    sciencedirect.com/science/article/pii/S2666379122002221
  99. www.sciencedirect.com www.sciencedirect.com
    Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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  100. www.medrxiv.org www.medrxiv.org
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the transcriptional activity of STAT3 by a novel fusion protein
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  104. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  105. Jun 2022
  106. 52.53.155.43 52.53.155.43
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  107. 52.53.155.43 52.53.155.43
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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  112. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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  113. www.sciencedirect.com www.sciencedirect.com
    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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  115. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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      RRID: Addgene_12259

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  116. www.sciencedirect.com www.sciencedirect.com
    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2405471222002241
  117. www.sciencedirect.com www.sciencedirect.com
    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes
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  120. www.sciencedirect.com www.sciencedirect.com
    Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs
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  121. www.sciencedirect.com www.sciencedirect.com
    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
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  122. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  123. May 2022
  124. link.springer.com link.springer.com
    Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation
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  125. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
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  126. www.sciencedirect.com www.sciencedirect.com
    HIV-1 exploits the Fanconi anemia pathway for viral DNA integration
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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  128. www.sciencedirect.com www.sciencedirect.com
    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interpretation of cancer mutations using a multi-scale map of protein systems
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  130. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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  131. www.sciencedirect.com www.sciencedirect.com
    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
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  133. www.sciencedirect.com www.sciencedirect.com
    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
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      DOI: 10.1016/j.ebiom.2022.104060

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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
    1
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  135. aacrjournals.org aacrjournals.org
    Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma
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  136. www.sciencedirect.com www.sciencedirect.com
    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
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  138. www.sciencedirect.com www.sciencedirect.com
    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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  139. www.nature.com www.nature.com
    Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
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  140. www.sciencedirect.com www.sciencedirect.com
    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    SETD4-mediated KU70 methylation suppresses apoptosis
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    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
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    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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  144. www.sciencedirect.com www.sciencedirect.com
    Synthetic Carbohydrate Binding Agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2.
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  145. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568653/
  147. www.sciencedirect.com www.sciencedirect.com
    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
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    sciencedirect.com/science/article/pii/S0092867422004433
  148. Apr 2022
  149. www.nature.com www.nature.com
    TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
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  150. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
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  151. www.sciencedirect.com www.sciencedirect.com
    Establishing transgenic murine esophageal organoids
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    sciencedirect.com/science/article/pii/S2666166722001976
  152. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
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  154. www.sciencedirect.com www.sciencedirect.com
    In vitro and in vivo assay of the ER lipid scramblase TMEM41B
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    sciencedirect.com/science/article/pii/S2666166722002131
  155. www.sciencedirect.com www.sciencedirect.com
    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
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    sciencedirect.com/science/article/pii/S1550413122001267
  156. www.sciencedirect.com www.sciencedirect.com
    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    sciencedirect.com/science/article/pii/S1097276522002696
  157. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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  158. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
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    sciencedirect.com/science/article/pii/S2211124722004545
  159. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
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    sciencedirect.com/science/article/pii/S2211124722004508
  160. www.sciencedirect.com www.sciencedirect.com
    Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
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  161. www.sciencedirect.com www.sciencedirect.com
    Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling
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  162. www.sciencedirect.com www.sciencedirect.com
    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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  163. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
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  164. www.sciencedirect.com www.sciencedirect.com
    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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  165. www.sciencedirect.com www.sciencedirect.com
    Rapid establishment of human colonic organoid knockout lines
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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  167. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
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  169. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
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  171. www.sciencedirect.com www.sciencedirect.com
    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  172. www.sciencedirect.com www.sciencedirect.com
    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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  174. Mar 2022
  175. elifesciences.org elifesciences.org
    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
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  176. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac178/6553119
  177. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
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    1. scibot 30 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722003035
  178. www.sciencedirect.com www.sciencedirect.com
    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    sciencedirect.com/science/article/pii/S1097276522002192
  179. www.sciencedirect.com www.sciencedirect.com
    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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    sciencedirect.com/science/article/pii/S1074761322001248
  180. www.sciencedirect.com www.sciencedirect.com
    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
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    sciencedirect.com/science/article/pii/S2405471222000849
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
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    ncbi.nlm.nih.gov/pmc/articles/PMC8945883/
  182. 52.53.155.43 52.53.155.43
    Optochemical Control of mTOR Signaling and mTOR-Dependent Autophagy
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  183. www.sciencedirect.com www.sciencedirect.com
    The mTOR chromatin-bound interactome in prostate cancer
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    sciencedirect.com/science/article/pii/S2211124722002753
  184. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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  185. www.sciencedirect.com www.sciencedirect.com
    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
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    sciencedirect.com/science/article/pii/S2211124722002741
  186. www.nature.com www.nature.com
    Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer
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  188. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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  189. www.sciencedirect.com www.sciencedirect.com
    Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations
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  191. www.sciencedirect.com www.sciencedirect.com
    Generation of highly pure motor neurons from human induced pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2666166722001034
  192. www.sciencedirect.com www.sciencedirect.com
    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
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  195. www.sciencedirect.com www.sciencedirect.com
    Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms
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    sciencedirect.com/science/article/pii/S2211124722002091
  196. www.sciencedirect.com www.sciencedirect.com
    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
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  197. www.sciencedirect.com www.sciencedirect.com
    Local hyperthermia therapy induces browning of white fat and treats obesity
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  198. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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      DOI: 10.1158/2767-9764.CRC-21-0103

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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  199. www.nature.com www.nature.com
    Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
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      DOI: 10.1038/s41377-022-00729-4

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    nature.com/articles/s41377-022-00729-4
  200. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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      DOI: 10.1038/s41596-021-00669-0

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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
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      DOI: 10.7554/eLife.65421

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  202. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
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      DOI: 10.7554/eLife.66869

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    elifesciences.org/articles/66869
  203. www.sciencedirect.com www.sciencedirect.com
    Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough
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