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  1. Aug 2021
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    Scalable, FACS-Free Genome-Wide Phenotypic Screening
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    ebiomedicine.com/article/S2352-3964(17)30151-2/abstract
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    Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages
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    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
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    Rigosertib induces mitotic arrest and apoptosis in RAS-mutated rhabdomyosarcoma and neuroblastoma
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    Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis
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    Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members
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    Lower Airway Dysbiosis Affects Lung Cancer Progression
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    Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection
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    Inhibitor of ppGalNAc-T3-mediated O-glycosylation blocks cancer cell invasiveness and lowers FGF23 levels
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    Single-cell transcriptomic landscape reveals tumor specific innate lymphoid cells associated with colorectal cancer progression
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  33. Jul 2021
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    Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells
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    Expression of miRNAs from the Imprinted DLK1/DIO3 Locus Signals the Osteogenic Potential of Human Pluripotent Stem Cells
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    Regulatory T Cells in an Endogenous Mouse Lymphoma Recognize Specific Antigen Peptides and Contribute to Immune Escape
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    Extracellular vesicles from oviductal isthmus and ampulla stimulate the induced acrosome reaction and signaling events associated with capacitation in bovine spermatozoa
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    GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing Sarcoma
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    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
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    Evaluation of Newcastle Disease Virus Mediated Dendritic Cell Activation and Cross‐priming Tumor‐specific Immune Responses Ex Vivo
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    The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells
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    Biological characterization of conserved residues within the cytoplasmic tail of the Pichinde arenaviral glycoprotein subunit 2 (GP2)
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    Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
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    Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules
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  46. link.springer.com link.springer.com
    Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy
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    Fractalkine Modulates Microglia Metabolism in Brain Ischemia
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    Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells
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    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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    GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability
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  53. journals.sagepub.com journals.sagepub.com
    miR-98 reduces endothelial dysfunction by protecting blood–brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model - David L Bernstein, Viviana Zuluaga-Ramirez, Sachin Gajghate, Nancy L Reichenbach, Boris Polyak, Yuri Persidsky, Slava Rom,
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  54. elifesciences.org elifesciences.org
    Natural Tr1-like cells do not confer long-term tolerogenic memory
    1
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  55. www.oncotarget.com www.oncotarget.com
    Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone
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    SRXN1 is Necessary for Resolution of GnRH-induced Oxidative Stress and Induction of Gonadotropin Gene Expression
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  57. elifesciences.org elifesciences.org
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    NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
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    High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype
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  61. www.nature.com www.nature.com
    Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary
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    Urothelial organoids originating from Cd49f high mouse stem cells display Notch-dependent differentiation capacity
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    The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins
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    The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
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  65. insight.jci.org insight.jci.org
    ROR1-CAR T-cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models
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    CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment
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    Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing
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    Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice
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    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    CD16‐158‐Valine Chimeric Receptor T Cells Overcome the Resistance of Kras‐Mutated Colorectal Carcinoma Cells to Cetuximab
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    Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation
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  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages
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    A double blinded, placebo-controlled pilot study to examine reduction of CD34<sup>+</sup>/CD117<sup>+</sup>/CD133<sup>+</sup> lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma
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  81. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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      DOI: 10.7554/eLife.64148

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    Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
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      DOI: 10.1016/j.cell.2018.10.001

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    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
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    Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
    1
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      DOI: 10.1016/j.cell.2018.09.042

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    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
    1
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      DOI: 10.1016/j.devcel.2018.10.001

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  86. www.sciencedirect.com www.sciencedirect.com
    IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
    1
    1. scibot 29 Jul 2021
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2019.10.097

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    Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells
    1
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      DOI: 10.1016/j.celrep.2019.10.079

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    Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor
    1
    1. scibot 29 Jul 2021
      RRID: SCR_008520

      DOI: 10.1016/j.celrep.2019.10.012

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    Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1016/j.immuni.2019.10.008

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    Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD
    1
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      DOI: 10.1016/j.celrep.2019.08.052

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    sciencedirect.com/science/article/pii/S2211124719311003
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    Estrogen Regulates the Satellite Cell Compartment in Females
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1016/j.celrep.2019.06.025

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    Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
    1
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      DOI: 10.1016/j.stem.2019.06.003

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  93. www.hindawi.com www.hindawi.com
    Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists
    1
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      DOI: 10.1155/2019/7692973

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  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HO‐1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition
    1
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      DOI: 10.1002/ijc.32611

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  95. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
    1
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      DOI: 10.7554/eLife.48318

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  96. elifesciences.org elifesciences.org
    Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence
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      DOI: 10.7554/eLife.46677

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  97. www.nature.com www.nature.com
    Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1038/s41598-019-48635-x

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  98. wellcomeopenresearch.org wellcomeopenresearch.org
    Testing the role of SOX15 in human primordial germ cell fate
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      FlowJo

      DOI: 10.12688/wellcomeopenres.15381.1

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  99. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14768

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  100. link.springer.com link.springer.com
    Differentiation of adipose-derived stem cells to functional CD105<Superscript>neg</Superscript> CD73<Superscript>low</Superscript> melanocyte precursors guided by defined culture condition
    1
    1. scibot 29 Jul 2021
      FlowJo

      DOI: 10.1186/s13287-019-1364-0

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  101. www.frontiersin.org www.frontiersin.org
    Chronic Ly49H Receptor Engagement in vivo Decreases NK Cell Response to Stimulation Through ITAM-Dependent and Independent Pathways Both in vitro and in vivo
    1
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      FlowJo

      DOI: 10.3389/fimmu.2019.01692

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  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
    1
    1. scibot 29 Jul 2021
      FlowJo

      DOI: 10.1002/ijc.32594

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  103. jem.rupress.org jem.rupress.org
    Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis
    1
    1. scibot 29 Jul 2021
      FlowJo

      DOI: 10.1084/jem.20180722

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  104. www.frontiersin.org www.frontiersin.org
    Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis
    1
    1. scibot 29 Jul 2021
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      DOI: 10.3389/fonc.2019.00632

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding
    1
    1. scibot 29 Jul 2021
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      DOI: 10.7554/eLife.42271

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  106. www.nature.com www.nature.com
    Standard screening methods underreport AAV-mediated transduction and gene editing
    1
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      DOI: 10.1038/s41467-019-11321-7

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  107. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Invasion by activated macrophages requires delivery of nascent MT1‐MMP through late endosomes/lysosomes to the cell surface
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1111/tra.12675

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  108. journals.plos.org journals.plos.org
    Inflammatory monocytes provide a niche for Salmonella expansion in the lumen of the inflamed intestine
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      DOI: 10.1371/journal.ppat.1007847

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lactational High-Fat Diet Exposure Programs Metabolic Inflammation and Bone Marrow Adiposity in Male Offspring
    1
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      DOI: 10.3390/nu11061393

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  110. www.sciencedirect.com www.sciencedirect.com
    Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic Leukemia
    1
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      DOI: 10.1016/j.celrep.2019.06.069

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    sciencedirect.com/science/article/pii/S2211124719308496
  111. www.sciencedirect.com www.sciencedirect.com
    Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells
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      DOI: 10.1016/j.celrep.2019.06.084

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  112. link.springer.com link.springer.com
    Expression of Breast Cancer-Related Epitopes Targeting the IGF-1 Receptor in Chimeric Human Parvovirus B19 Virus-Like Particles
    1
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      DOI: 10.1007/s12033-019-00198-y

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  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impairing Temozolomide Resistance Driven by Glioma Stem‐like Cells with adjuvant Immunotherapy Targeting O‐acetyl GD2 Ganglioside
    1
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      FlowJo

      DOI: 10.1002/ijc.32533

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  114. mcr.aacrjournals.org mcr.aacrjournals.org
    PARP Inhibition Induces Enrichment of DNA Repair–Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells
    1
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      FlowJo

      DOI: 10.1158/1541-7786.MCR-18-0594

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  115. cancerres.aacrjournals.org cancerres.aacrjournals.org
    HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
    1
    1. scibot 29 Jul 2021
      FlowJo

      DOI: 10.1158/0008-5472.CAN-18-1377

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  116. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors
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      DOI: 10.1016/j.chembiol.2017.11.007

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  117. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine‐induced status epileptics
    1
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      DOI: 10.1002/cne.24734

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  118. www.sciencedirect.com www.sciencedirect.com
    NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
    1
    1. scibot 29 Jul 2021
      RRID:SCR_008520

      DOI: 10.1016/j.cell.2018.10.028

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  119. www.sciencedirect.com www.sciencedirect.com
    Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells
    1
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      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2018.10.074

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    sciencedirect.com/science/article/pii/S2211124718316784
  120. www.sciencedirect.com www.sciencedirect.com
    Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
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      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2019.11.106

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  121. www.sciencedirect.com www.sciencedirect.com
    Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow
    1
    1. scibot 28 Jul 2021
      RRID: SCR_008520

      DOI: 10.1016/j.immuni.2019.05.002

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  122. www.sciencedirect.com www.sciencedirect.com
    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
    1
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      RRID: SCR_008520

      DOI: 10.1016/j.celrep.2018.12.072

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    sciencedirect.com/science/article/pii/S2211124718320175
  123. www.sciencedirect.com www.sciencedirect.com
    Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization
    1
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      RRID:SCR_008520

      DOI: 10.1016/j.chom.2019.03.008

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    sciencedirect.com/science/article/pii/S193131281930160X
  124. www.sciencedirect.com www.sciencedirect.com
    Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells
    1
    1. scibot 28 Jul 2021
      RRID: SCR_008520

      DOI: 10.1016/j.immuni.2019.03.002

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    sciencedirect.com/science/article/pii/S1074761319300925
  125. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Circuit Fragility Influences HIV Proviral Fate
    1
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      RRID: SCR_008520

      DOI: 10.1016/j.celrep.2019.03.007

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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity
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    Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
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    Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody
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    Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages
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    The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
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    Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
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    The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
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    JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells
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    PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients
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  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Absence of infiltrating peripheral myeloid cells in the brains of mouse models of lysosomal storage disorders
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    In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity
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    Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia
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    Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity
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    Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
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    T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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    Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T Cells
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    Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens
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    Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons
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    Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication
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    An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis
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    Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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    Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain
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    Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
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  189. elifesciences.org elifesciences.org
    Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling
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    Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
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      Flowjo

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  191. www.jneurosci.org www.jneurosci.org
    Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke
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      FlowJo software

      DOI: 10.1523/JNEUROSCI.1532-14.2015

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    jneurosci.org/content/35/20/7777.long
  192. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.immuni.2018.11.018

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