2,250 Matching Annotations
  1. Jun 2022
  2. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
    1
    1. scibot 02 Jun 2022
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S1097276522004427
  3. May 2022
  4. link.springer.com link.springer.com
    Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation
    1
    1. scibot 28 May 2022
      RRID:Addgene_12260

      DOI: 10.1007/s00018-022-04312-3

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    link.springer.com/article/10.1007/s00018-022-04312-3
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    DDX41 is required for cGAS-STING activation against DNA virus infection
    1
    1. scibot 26 May 2022
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    sciencedirect.com/science/article/pii/S2211124722006295
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    Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies
    1
    1. scibot 26 May 2022
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    sciencedirect.com/science/article/pii/S2211124722006143
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
    1
    1. scibot 26 May 2022
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    sciencedirect.com/science/article/pii/S1934590922001709
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
    1
    1. scibot 26 May 2022
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    sciencedirect.com/science/article/pii/S153458072200332X
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    F-box protein FBXO41 suppresses breast cancer growth by inducing autophagic cell death through facilitating proteasomal degradation of oncogene SKP2
    1
    1. scibot 25 May 2022
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S1357272522000735
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
    1
    1. scibot 24 May 2022
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-21-0810

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122831/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
    1
    1. scibot 24 May 2022
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      DOI: 10.7554/eLife.75594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
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    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
    1
    1. scibot 19 May 2022
      RRID: Addgene_12260

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    sciencedirect.com/science/article/pii/S2352396422002419
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    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
    1
    1. scibot 19 May 2022
      Plasmid_12260

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    sciencedirect.com/science/article/pii/S258900422200596X
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    Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
    1
    1. scibot 19 May 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2022.104349

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    sciencedirect.com/science/article/pii/S2589004222006204
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
    1
    1. scibot 18 May 2022
      RRID:Addgene_12260

      DOI: 10.7554/eLife.76541

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    ncbi.nlm.nih.gov/pmc/articles/PMC9094746/
  16. www.nature.com www.nature.com
    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
    1
    1. scibot 17 May 2022
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    nature.com/articles/s41467-022-30362-z
  17. www.sciencedirect.com www.sciencedirect.com
    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
    1
    1. scibot 13 May 2022
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    sciencedirect.com/science/article/pii/S2589004222005491
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
    1
    1. scibot 13 May 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9097013/
  19. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
    1
    1. scibot 13 May 2022
      RRID:Addgene_12260

      DOI: 10.1158/2159-8290.CD-21-1006

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    aacrjournals.org/cancerdiscovery/article/12/5/1314/694563/Melanoma-Secreted-Amyloid-Beta-Suppresses
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    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
    1
    1. scibot 13 May 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.110790

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    sciencedirect.com/science/article/pii/S2211124722005575
  21. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
    2
    1. scibot 12 May 2022
      Addgene #12260

      DOI: 10.1016/j.molcel.2022.04.015

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    2. scibot 12 May 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2022.04.015

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    sciencedirect.com/science/article/pii/S1097276522003264
  22. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
    1
    1. scibot 12 May 2022
      plasmid_12260

      DOI: 10.1016/j.cell.2022.04.019

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    sciencedirect.com/science/article/pii/S0092867422004664
  23. www.nature.com www.nature.com
    Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
    1
    1. scibot 12 May 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41596-022-00695-6

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    nature.com/articles/s41596-022-00695-6
  24. www.sciencedirect.com www.sciencedirect.com
    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
    1
    1. scibot 11 May 2022
      Addgene12260

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    sciencedirect.com/science/article/pii/S2211124722005642
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    SETD4-mediated KU70 methylation suppresses apoptosis
    1
    1. scibot 11 May 2022
      Addgene, Cat#12260

      DOI: 10.1016/j.celrep.2022.110794

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    sciencedirect.com/science/article/pii/S2211124722005617
  26. www.sciencedirect.com www.sciencedirect.com
    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
    1
    1. scibot 11 May 2022
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      DOI: 10.1016/j.celrep.2022.110792

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    sciencedirect.com/science/article/pii/S2211124722005599
  27. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
    1
    1. scibot 11 May 2022
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      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  28. aacrjournals.org aacrjournals.org
    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
    1
    1. scibot 10 May 2022
      Addgene_12260

      DOI: 10.1158/2767-9764.CRC-22-0037

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    aacrjournals.org/cancerrescommun/article/2/5/293/696275/Repurposing-Itraconazole-and-Hydroxychloroquine-to
  29. www.science.org www.science.org
    Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
    1
    1. scibot 10 May 2022
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      DOI: 10.1126/sciadv.abn2748

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    science.org/doi/10.1126/sciadv.abn2748
  30. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
    1
    1. scibot 10 May 2022
      Plasmid_12260

      DOI: 10.1038/s41420-022-01044-y

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    nature.com/articles/s41420-022-01044-y
  31. www.sciencedirect.com www.sciencedirect.com
    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
    1
    1. scibot 04 May 2022
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      DOI: 10.1016/j.cell.2022.04.005

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    sciencedirect.com/science/article/pii/S0092867422004433
  32. www.nature.com www.nature.com
    Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
    1
    1. scibot 03 May 2022
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      DOI: 10.1038/s41467-022-29942-w

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    nature.com/articles/s41467-022-29942-w
  33. Apr 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
    1
    1. scibot 27 Apr 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  35. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
    1
    1. scibot 23 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41392-022-00946-8

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    nature.com/articles/s41392-022-00946-8
  36. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
    1
    1. scibot 22 Apr 2022
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      DOI: 10.1158/2326-6066.CIR-21-0806

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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  37. www.sciencedirect.com www.sciencedirect.com
    Establishing transgenic murine esophageal organoids
    1
    1. scibot 22 Apr 2022
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      DOI: 10.1016/j.xpro.2022.101317

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    sciencedirect.com/science/article/pii/S2666166722001976
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
    1
    1. scibot 22 Apr 2022
      plasmid_12260

      DOI: 10.3389/fonc.2022.766794

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    ncbi.nlm.nih.gov/pmc/articles/PMC9015667/
  39. www.sciencedirect.com www.sciencedirect.com
    In vitro and in vivo assay of the ER lipid scramblase TMEM41B
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.xpro.2022.101333

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    sciencedirect.com/science/article/pii/S2666166722002131
  40. www.sciencedirect.com www.sciencedirect.com
    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
    1
    1. scibot 21 Apr 2022
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    sciencedirect.com/science/article/pii/S1550413122001267
  41. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
    1
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    sciencedirect.com/science/article/pii/S1534580722002295
  42. www.sciencedirect.com www.sciencedirect.com
    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
    1
    1. scibot 21 Apr 2022
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    sciencedirect.com/science/article/pii/S1097276522002696
  43. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
      Plasmid_12260

      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  44. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
    1
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    sciencedirect.com/science/article/pii/S2211124722004545
  45. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
    1
    1. scibot 20 Apr 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2211124722004508
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    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    1. scibot 15 Apr 2022
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    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
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    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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    Rapid establishment of human colonic organoid knockout lines
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs
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    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
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    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  58. aacrjournals.org aacrjournals.org
    GFI1 cooperates with IKZF1/IKAROS to activate gene expression in T-cell acute lymphoblastic leukemia
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  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  60. Mar 2022
  61. elifesciences.org elifesciences.org
    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
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  62. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
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    Genome-wide analysis of haploinsufficiency in human embryonic stem cells
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    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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    A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis
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    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
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  70. 52.53.155.43 52.53.155.43
    Optochemical Control of mTOR Signaling and mTOR-Dependent Autophagy
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    The mTOR chromatin-bound interactome in prostate cancer
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants
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    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
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  75. www.embopress.org www.embopress.org
    CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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    Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
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  79. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms
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    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
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    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
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    Local hyperthermia therapy induces browning of white fat and treats obesity
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  86. www.nature.com www.nature.com
    Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
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  87. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
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      DOI: 10.7554/eLife.65421

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  91. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
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  92. www.sciencedirect.com www.sciencedirect.com
    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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    Recruitment of DNA to tumor-derived microvesicles
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  95. Feb 2022
  96. www.sciencedirect.com www.sciencedirect.com
    Generation of a pooled shRNA library for functional genomics screens
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    The transcriptional profile of adipose-derived stromal cells (ASC) mirrors the whitening of adipose tissue with age
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    High-throughput identification of autoantibodies that target the human exoproteome
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    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
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    An AMPKα2-specific phospho-switch controls lysosomal targeting for activation
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  101. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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    Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing
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  103. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
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  104. www.sciencedirect.com www.sciencedirect.com
    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C-type natriuretic peptide-induced PKA activation promotes endochondral bone formation in hypertrophic chondrocytes
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  106. www.sciencedirect.com www.sciencedirect.com
    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
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  107. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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  108. www.sciencedirect.com www.sciencedirect.com
    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing is an alternate oncogenic pathway activation mechanism in glioma
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    Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts
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  112. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network
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    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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    Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties
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    Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death
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    Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
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  119. Jan 2022
  120. www.sciencedirect.com www.sciencedirect.com
    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis
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  122. www.sciencedirect.com www.sciencedirect.com
    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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  123. www.sciencedirect.com www.sciencedirect.com
    The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression
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  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
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  127. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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  128. www.sciencedirect.com www.sciencedirect.com
    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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  129. www.nature.com www.nature.com
    Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
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      DOI: 10.1038/s42003-021-02953-x

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    nature.com/articles/s42003-021-02953-x
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
    1
    1. scibot 15 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2021.12.026

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    ncbi.nlm.nih.gov/pmc/articles/PMC8695127/
  131. www.sciencedirect.com www.sciencedirect.com
    Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
    1
    1. scibot 12 Jan 2022
      Addgene12260

      DOI: 10.1016/j.cell.2021.12.021

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    sciencedirect.com/science/article/pii/S0092867421014847
  132. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    2
    1. scibot 12 Jan 2022
      Addgene plasmid # 12260

      DOI: 10.1016/j.celrep.2021.110233

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      plasmid_12260

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  133. www.sciencedirect.com www.sciencedirect.com
    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
    1
    1. scibot 12 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103621

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    sciencedirect.com/science/article/pii/S2589004221015911
  134. www.sciencedirect.com www.sciencedirect.com
    Identification and functional characterization of transcriptional activators in human cells
    1
    1. scibot 11 Jan 2022
      Addgene_12260

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    sciencedirect.com/science/article/pii/S1097276521010704
  135. www.sciencedirect.com www.sciencedirect.com
    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
    1
    1. scibot 08 Jan 2022
      plasmid_12

      DOI: 10.1016/j.celrep.2021.110226

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    sciencedirect.com/science/article/pii/S2211124721017307
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2
    1
    1. scibot 07 Jan 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2021.110256

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    ncbi.nlm.nih.gov/pmc/articles/PMC8695190/
  137. www.sciencedirect.com www.sciencedirect.com
    Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice
    1
    1. scibot 05 Jan 2022
      12260

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    sciencedirect.com/science/article/pii/S2352396421005971
  138. www.sciencedirect.com www.sciencedirect.com
    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
    1
    1. scibot 05 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.110197

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    sciencedirect.com/science/article/pii/S2211124721017010
  139. Dec 2021
  140. www.sciencedirect.com www.sciencedirect.com
    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
    1
    1. scibot 29 Dec 2021
      plasmid_12260

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    sciencedirect.com/science/article/pii/S2589004221015753
  141. www.cell.com www.cell.com
    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
    1
    1. scibot 29 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.110155

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    cell.com/cell-reports/fulltext/S2211-1247(21)01651-X
  142. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
    1
    1. scibot 22 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1158/1535-7163.MCT-20-1034

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    mct.aacrjournals.org/content/20/11/2228
  143. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
    1
    1. scibot 15 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1186/s40170-021-00277-2

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    link.springer.com/article/10.1186/s40170-021-00277-2
  144. www.sciencedirect.com www.sciencedirect.com
    Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1
    1
    1. scibot 15 Dec 2021
      Plasmid_12260

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    sciencedirect.com/science/article/pii/S2211124721015989
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
    1
    1. scibot 11 Dec 2021
      AddgenePlasmid# 12260

      DOI: 10.1016/j.isci.2021.103448

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633987/
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
    1
    1. scibot 11 Dec 2021
      plasmid_12260

      DOI: 10.1038/s41467-021-26498-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC8605023/
  147. elifesciences.org elifesciences.org
    Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
    1
    1. scibot 11 Dec 2021
      Plasmid_12260

      DOI: 10.7554/eLife.73027

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    elifesciences.org/articles/73027
  148. www.sciencedirect.com www.sciencedirect.com
    Structure, mechanism, and inhibition of Hedgehog acyltransferase
    1
    1. scibot 10 Dec 2021
      plasmid_12260

      DOI: 10.1016/j.molcel.2021.11.018

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    sciencedirect.com/science/article/pii/S1097276521009989
  149. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
    1
    1. scibot 08 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.immuni.2021.11.006

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    sciencedirect.com/science/article/pii/S1074761321004970
  150. www.sciencedirect.com www.sciencedirect.com
    Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation
    1
    1. scibot 07 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.jbc.2021.101459

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    sciencedirect.com/science/article/pii/S0021925821012680
  151. www.sciencedirect.com www.sciencedirect.com
    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
    1
    1. scibot 03 Dec 2021
      Cat#12260

      DOI: 10.1016/j.cell.2021.11.011

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    sciencedirect.com/science/article/pii/S009286742101326X
  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
    1
    1. scibot 02 Dec 2021
      AddgenePlasmid #12260

      DOI: 10.1371/journal.pbio.3001432

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    ncbi.nlm.nih.gov/pmc/articles/PMC8610276/
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetically Edited Hepatic Cells Expressing the NTCP-S267F Variant are Resistant to Hepatitis B Virus Infection
    1
    1. scibot 02 Dec 2021
      Addgene_12260

      DOI: 10.1016/j.omtm.2021.11.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608598/
  154. Nov 2021
  155. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
    1
    1. scibot 30 Nov 2021
      Cat# 12260

      DOI: 10.1016/j.molcel.2021.11.002

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  156. www.sciencedirect.com www.sciencedirect.com
    Immuno-transcriptomic profiling of extracranial pediatric solid malignancies
    1
    1. scibot 30 Nov 2021
      Addgene_12260

      DOI: 10.1016/j.celrep.2021.110047

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    sciencedirect.com/science/article/pii/S2211124721015333
  157. www.sciencedirect.com www.sciencedirect.com
    Deciphering cell signaling networks with massively multiplexed biosensor barcoding
    1
    1. scibot 30 Nov 2021
      plasmid_12260

      DOI: 10.1016/j.cell.2021.11.005

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    sciencedirect.com/science/article/pii/S0092867421013209
  158. elifesciences.org elifesciences.org
    Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
    1
    1. scibot 24 Nov 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.65109

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    elifesciences.org/articles/65109
  159. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
    1
    1. scibot 24 Nov 2021
      Addgene_12260

      DOI: 10.1016/j.celrep.2021.110056

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    sciencedirect.com/science/article/pii/S2211124721015424
  160. www.sciencedirect.com www.sciencedirect.com
    PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
    1
    1. scibot 23 Nov 2021
      Addgene, Cat# 12260

      DOI: 10.1016/j.chembiol.2021.11.001

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    sciencedirect.com/science/article/pii/S2451945621004785
  161. www.sciencedirect.com www.sciencedirect.com
    Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2
    1
    1. scibot 18 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103295

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    sciencedirect.com/science/article/pii/S2589004221012645
  162. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      plasmid_12260

      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
  163. www.sciencedirect.com www.sciencedirect.com
    Modulating mesendoderm competence during human germ layer differentiation
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    1. scibot 10 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109990

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    sciencedirect.com/science/article/pii/S2211124721014698
  164. www.sciencedirect.com www.sciencedirect.com
    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
    1
    1. scibot 10 Nov 2021
      Plasmid_12260

      DOI: 10.1016/j.celrep.2021.109981

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    sciencedirect.com/science/article/pii/S2211124721014601
  165. www.nature.com www.nature.com
    RNA-responsive elements for eukaryotic translational control
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    1. scibot 06 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1038/s41587-021-01068-2

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    nature.com/articles/s41587-021-01068-2
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Improved CRISPR/dCas9 Interference Tool for Neuronal Gene Suppression
    1
    1. scibot 05 Nov 2021
      plasmid_12260

      DOI: 10.3389/fgeed.2020.00009

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    ncbi.nlm.nih.gov/pmc/articles/PMC8525373/
  167. www.sciencedirect.com www.sciencedirect.com
    A multi-omic single-cell landscape of human gynecologic malignancies
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    1. scibot 05 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2021.10.013

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    sciencedirect.com/science/article/pii/S109727652100842X
  168. Oct 2021
  169. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
    1
    1. scibot 29 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103224

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    sciencedirect.com/science/article/pii/S2589004221011925
  170. www.jneurosci.org www.jneurosci.org
    Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells
    1
    1. scibot 27 Oct 2021
      Addgene_12260

      DOI: 10.1523/JNEUROSCI.3243-20.2021

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    jneurosci.org/content/41/42/8710
  171. www.sciencedirect.com www.sciencedirect.com
    GCN2 adapts protein synthesis to scavenging-dependent growth
    1
    1. scibot 27 Oct 2021
      Addgene_12260

      DOI: 10.1016/j.cels.2021.09.014

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    sciencedirect.com/science/article/pii/S2405471221003823
  172. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
    1
    1. scibot 23 Oct 2021
      12260

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    sciencedirect.com/science/article/pii/S1097276521008340
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
    1
    1. scibot 23 Oct 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.65672

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523159/
  174. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
    1
    1. scibot 22 Oct 2021
      RRID:Addgene 12260

      DOI: 10.1016/j.cub.2021.09.067

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    sciencedirect.com/science/article/pii/S0960982221013233
  175. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
    1
    1. scibot 21 Oct 2021
      12260

      DOI: 10.1016/j.molcel.2021.09.029

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    sciencedirect.com/science/article/pii/S109727652100798X
  176. www.sciencedirect.com www.sciencedirect.com
    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
    1
    1. scibot 21 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
  177. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
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    1. scibot 21 Oct 2021
      Addgene_12260

      DOI: 10.1016/j.celrep.2021.109873

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    sciencedirect.com/science/article/pii/S2211124721013401
  178. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 20 Oct 2021
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      DOI: 10.1111/bph.15631

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15631
  179. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
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    1. scibot 14 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A highly potent antibody effective against SARS-CoV-2 variants of concern
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      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109814

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    ncbi.nlm.nih.gov/pmc/articles/PMC8452523/
  181. www.sciencedirect.com www.sciencedirect.com
    Cancer cell immune mimicry delineates onco-immunologic modulation
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    1. scibot 11 Oct 2021
      Addgene_12260

      DOI: 10.1016/j.isci.2021.103133

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    sciencedirect.com/science/article/pii/S2589004221011019
  182. www.sciencedirect.com www.sciencedirect.com
    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
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    1. scibot 05 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2021.100870

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    sciencedirect.com/science/article/pii/S2666166721005761
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system
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      DOI: 10.1038/s41598-021-98657-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
  184. Sep 2021
  185. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells
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    1. scibot 30 Sep 2021
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      DOI: 10.1111/gtc.12893

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    onlinelibrary.wiley.com/doi/10.1111/gtc.12893
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    1. scibot 28 Sep 2021
      RRID:Addgene_12260

      DOI: 10.1158/2643-3230.bcd-21-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ observation of mitochondrial biogenesis as the early event of apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8441175/
  188. www.sciencedirect.com www.sciencedirect.com
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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      DOI: 10.1016/j.xcrm.2021.100394

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    sciencedirect.com/science/article/pii/S2666379121002524
  189. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
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      RRID: Addgene_12260

      DOI: 10.1016/j.cell.2021.09.001

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    sciencedirect.com/science/article/pii/S0092867421010485
  190. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
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    1. scibot 24 Sep 2021
      12260

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    sciencedirect.com/science/article/pii/S1097276521007292
  191. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    sciencedirect.com/science/article/pii/S1097276521007139
  192. www.sciencedirect.com www.sciencedirect.com
    Assessing the Wnt-reactivity of cytonemes of mouse embryonic stem cells using a bioengineering approach
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    1. scibot 21 Sep 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2021.100813

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    sciencedirect.com/science/article/pii/S2666166721005190
  193. www.sciencedirect.com www.sciencedirect.com
    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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    1. scibot 17 Sep 2021
      Addgene_12260

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    sciencedirect.com/science/article/pii/S1097276521006961
  194. www.sciencedirect.com www.sciencedirect.com
    Pro-inflammatory and proliferative microglia drive progression of glioblastoma
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    1. scibot 16 Sep 2021
      12260

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    sciencedirect.com/science/article/pii/S2211124721011670
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFP36L2 Role in Thyroid Functionality
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    1. scibot 14 Sep 2021
      RRID:Addgene_12260

      DOI: 10.3390/ijms22179379

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    ncbi.nlm.nih.gov/pmc/articles/PMC8431063/
  196. www.sciencedirect.com www.sciencedirect.com
    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    1. scibot 11 Sep 2021
      Cat# 12260

      DOI: 10.1016/j.cmet.2021.08.012

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    sciencedirect.com/science/article/pii/S1550413121003752
  197. www.sciencedirect.com www.sciencedirect.com
    Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2
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    1. scibot 10 Sep 2021
      Plasmid_12260

      DOI: 10.1016/j.neuron.2021.08.011

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    sciencedirect.com/science/article/pii/S0896627321006085
  198. www.sciencedirect.com www.sciencedirect.com
    Cilium induction triggers differentiation of glioma stem cells
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      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109656

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    sciencedirect.com/science/article/pii/S2211124721010998
  199. www.sciencedirect.com www.sciencedirect.com
    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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    1. scibot 04 Sep 2021
      12260

      DOI: 10.1016/j.devcel.2021.08.006

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    sciencedirect.com/science/article/pii/S1534580721006365
  200. link.springer.com link.springer.com
    Methods for Quantitative Assessment of <IndexTerm ID="ITerm1">Protein Degradation</IndexTerm>
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_12260

      DOI: 10.1007/978-1-0716-1665-9_13

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    link.springer.com/protocol/10.1007/978-1-0716-1665-9_13