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  1. Jan 2026
    1. In biology the term "high-energy bond" is used to describe an exergonic reaction involving the hydrolysis of the bond in question that results in a "large," negative change in free energy.

      This helps clear up some previous confusions I've had regarding the energy of the chemical bonds of molecules.

      In AP Chemistry, I was taught that in order to break bonds, you use energy to break that bond. Like smashing something with a hammer, you use energy to swing the hammer and strike the substrate.

      However, in pervious Biology courses, I was told to simply understand that the bonds of molecules like ATP and Glucose store a lot of energy and release it when the bond is broken or changed.

      I'm glad that I was able to clear this up with a stronger understanding of Gibb's Free Energy.