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  1. Sep 2025
    1. Abstract

      General / Study Terms

      AHN – Adult Hippocampal Neurogenesis

      AD – Alzheimer’s Disease

      PMD – Post-Mortem Delay

      DG – Dentate Gyrus

      DGC – Dentate Granule Cell

      GCL – Granule Cell Layer

      ML – Molecular Layer

      SGZ – Subgranular Zone

      H – Hilus

      EC – Entorhinal Cortex

      CA1, CA3 – Cornu Ammonis hippocampal subfields

      Pyr – Pyramidal layer

      Cell Markers & Proteins

      DCX – Doublecortin (marker of immature neurons)

      Prox1 – Prospero Homeobox 1 (granule cell fate marker)

      PSA-NCAM – Polysialic Acid–Neural Cell Adhesion Molecule (immature neuron marker)

      CR – Calretinin (calcium-binding protein; early immature neuron marker)

      CB – Calbindin (calcium-binding protein; marker of more mature neurons)

      NeuN – Neuronal Nuclei (marker of mature neurons)

      βIII-tubulin – Cytoskeletal protein (neuronal identity marker)

      Tau (pTau) – Microtubule-associated protein; phosphorylated tau linked to AD pathology

      β-amyloid (Aβ) – Amyloid-beta peptide, forms plaques in AD

      Methods & Technical

      NaBH₄ – Sodium borohydride (used in tissue treatment)

      HC-AR – Heat and Chemical Antigen Retrieval (histological technique)

      CI – Confidence Interval

      ANOVA – Analysis of Variance (statistical test)

      s.e.m. – Standard Error of the Mean