According to this statement, those who are diagnosed with RME sleep behavior syndrome have an increased risk of developing Parkinson’s disease. A number of questions arise from this statement.

• What are the characteristics of REM sleep behavior syndrome? How does it manifest itself? How often does it manifest itself? Do those individuals in which it manifests itself more frequently have an increased chance of developing Parkinson’s disease?
• What is the neurological mechanism that is causing REM sleep behavior syndrome? Is the mechanism that is causing this the actual cause of the reduction of dopamine production that is characteristic of Parkinson’s disease?