Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function
AssayResult: 23.2
AssayResultAssertion: Abnormal
ReplicateCount: 14
StandardErrorMean: 7.1
Comment: This variant had partial loss of function of peak current (10-50% of wildtype) and a >10mV loss of function shift in Vhalf activation, therefore it was considered abnormal (in vitro features consistent with Brugada Syndrome Type 1). (Personal communication: A. Glazer)