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  1. Sep 2021
  2. www.cancer-research-network.com www.cancer-research-network.com
    Afatinib is an Irreversible and Orally Active EGFR Family Inhibitor - Network of Cancer Research
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    1. dwmackey 02 Sep 2021
      Thus, Afatinib is an irreversible EGFR family inhibitor. The IC50s are 0.5 nM, 0.4 nM, 10 nM, and 14 nM for EGFR wt, EGFR L858R, EGFR L858R/T790M, and HER2, respectively.
      afatinib ERBB1 ERBB2 EGFR HER2
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    cancer-research-network.com/lung-cancer/afatinib-is-an-irreversible-and-orally-active-egfr-family-inhibitor/2021-01-18/