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  1. Jan 2021
  2. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist
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    1. Drugs_and_Ethics 15 Jan 2021
      IC50 values for histamine-H1, dopamine-D2, and adrenergic-alpha 1 and -alpha 2 sites were 39-, 77-, 107-, and 166-fold higher

      Thus, ritanserin is highly selective for 5HT2 receptors. By comparison, ketanserin antagonizes.adrenergic alpha 1 in addition to serotonin receptors.

      ritanserin IC50
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    pubmed.ncbi.nlm.nih.gov/2860558/