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  1. Apr 2020
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    Cryo-EM structure of the human MLL1 core complex bound to the nucleosome
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    1. zhentg 01 Apr 2020
      distance between Lys37 on each H3 tail and the active site ofMLL1SETwas ~60 Å, allowing active-site access to H3 K4 and K9,but not to H3K27

      this distance betwen K37 and K4 may be similar to 60A, so that H3K4 methylation is possible

      MLL histone nucleosome

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