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  1. Apr 2026
    1. Urgent treatment for neoplasm consists of (1) cautious use of intravenous diuretics and (2) mediastinal irradiation, starting within 24 hours, with a treatment plan designed to give a high daily dose of radiation but a short total course of therapy to rapidly shrink the local tumor. Intensive radiation therapy combined with chemotherapy will palliate the process in up to 90% of patients. In patients with a subacute presentation, radiation therapy alone usually suffices. Chemotherapy is added if lymphoma or small-cell carcinoma is diagnosed

      endovascular stenting emerging as first-line therapy for rapid symptom relief, while definitive treatment targets the underlying cause

      Glucocorticoids (dexamethasone 4 mg every 6 hours) are commonly prescribed but lack robust supporting data; they may be more beneficial in lymphoma or thymoma and as prophylaxis against radiation-induced edema. [2-4] Importantly, SVC syndrome is no longer considered a medical emergency except in rare cases with life-threatening cerebral edema, laryngeal edema, or altered mental status. When thrombosis is present, catheter-directed thrombolysis or aspiration thrombectomy should be performed within 2-5 days of symptom onset before thrombus organization occurs. [3] The role of long-term anticoagulation after stenting remains unclear, though it is standard when significant thrombosis is present The American College of Chest Physicians recommends obtaining histologic diagnosis before treatment in suspected lung cancer cases, as stenting does not interfere with tissue diagnosis. [2] For small cell lung cancer (SCLC), chemotherapy alone is recommended as first-line treatment given rapid response rates. [2] For non-small cell lung cancer (NSCLC), radiation therapy and/or stent insertion are recommended, with response rates of 59% for chemotherapy and 63% for radiation therapy. [2] Patients with chemotherapy- or radiation-refractory disease should receive vascular stents For device-related thrombosis (catheters, pacemakers), catheter removal should be considered in conjunction with anticoagulation. [4] Endovascular therapy is first-line for device-related obstruction, while surgical bypass may be preferred for mediastinal fibrosis. [7] Both approaches show good mid-term patency, though secondary interventions are common (approximately 27-28%

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  2. Jun 2025
  3. Feb 2025
    1. Najtańsze chińskie auta w Polsce. Dominuje jedna marka

      Chinese cars with record sales growth in Poland, in January 1000% increase in registrations year-on-year (2 thousand), and their market share jumped to 5%; the most popular brand is MG (1 thousand units), ahead of e.g. Fiat, Citroën, Suzuki and Opel.

      In the whole of 2024, 11 thousand Chinese cars were registered, and in 2023 only 160.

      Prices of the cheapest Chinese cars:

      • MG3 PLN 73.5 thousand, 1.5 l engine
      • BAIC Beijing 3: PLN 79 thousand, 1.5 l engine
      • MG ZS Classic PLN 80 thousand, 1.5 l engine

      The cheapest hybrid: MG ZS Hybrid+: PLN 99 thousand, 1.5 l engine.

  4. Jul 2018
    1. Mg Citrate 0.26 ± 0.02 0.32 ± 0.03   0.33 ± 0.04*

      Interestingly, the superiority of magnesium citrate over other forms is most evident in salivary excretion, both acute and chronic. In particular, I had been led to believe that amino acid chelate was superior. Given that these results are consistent superior plasma levels, I take this to be reasonable evidence that the citrate form is superior for a given value of elemental magnesium. In this case, 300mg elemental Mg.