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72 Matching Annotations

Jul 2026
aacrjournals.org aacrjournals.org

IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2313
  
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aacrjournals.org/cancerres/article/86/8/2004/782636/IDH1-Reprograms-Nucleotide-Metabolism-by-Inducing
Jun 2026
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STAT3 interference-driven nanomodulators reverse lipid metabolism-associated chemoresistance and potentiate metalloimmunotherapy in breast cancer

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1. scibot 05 Jun 2026
  
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  DOI: 10.1016/j.xcrm.2026.102844
  
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sciencedirect.com/science/article/pii/S2666379126002612
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AMPK-p38 axis converts human pluripotent stem cells to naive state

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115569
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13122662/
Aug 2025
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Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells

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1. scibot 11 Aug 2025
  
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  DOI: 10.1038/s42255-025-01325-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12286850/
May 2025
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Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115680
  
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sciencedirect.com/science/article/pii/S2211124725004516
Apr 2025
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Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation

1
1. scibot 19 Apr 2025
  
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  DOI: 10.1186/s12915-025-02205-y
  
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link.springer.com/article/10.1186/s12915-025-02205-y
Mar 2025
www.biorxiv.org www.biorxiv.org

Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation

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1. scibot 07 Mar 2025
  
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  DOI: 10.1101/2025.02.21.639484
  
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biorxiv.org/content/10.1101/2025.02.21.639484v1
Feb 2025
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Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome

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1. scibot 20 Feb 2025
  
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  DOI: 10.1038/s41467-025-56928-1
  
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link.springer.com/article/10.1038/s41467-025-56928-1
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes

1
1. scibot 18 Jan 2025
  
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  DOI: 10.1038/s42004-024-01382-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11662004/
Dec 2024
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Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114789
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11639441/
Sep 2024
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Maternal high-fat diet alters Tet-mediated epigenetic regulation during heart development

1
1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110631
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11388159/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome

1
1. scibot 01 May 2024
  
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  DOI: 10.21203/rs.3.rs-4131804/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030528/
Jan 2024
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ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1

1
1. scibot 19 Jan 2024
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.devcel.2023.12.018
  
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sciencedirect.com/science/article/pii/S1534580723006986
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Selective Targeting of Human TET1 by Cyclic Peptide Inhibitors: Insights from Biochemical Profiling

1
1. scibot 18 Jan 2024
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.bmc.2024.117597
  
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sciencedirect.com/science/article/pii/S0968089624000117
Oct 2023
www.embopress.org www.embopress.org

Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes

1
1. scibot 20 Oct 2023
  
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  RRID:AB_10013602
  
  DOI: 10.15252/embj.2023113955
  
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embopress.org/doi/10.15252/embj.2023113955
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Standardized Computer-Assisted Analysis of 5-hmC Immunoreactivity in Dysplastic Nevi and Superficial Spreading Melanomas

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1. scibot 18 Oct 2023
  
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  RRID:AB_10013602
  
  DOI: 10.3390/ijms241914711
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10572721/
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Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness

1
1. scibot 13 Oct 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2023.113246
  
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sciencedirect.com/science/article/pii/S2211124723012585
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TET3 plays a critical role in white adipose development and diet-induced remodeling

1
1. scibot 06 Oct 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2023.113196
  
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sciencedirect.com/science/article/pii/S2211124723012081
Sep 2023
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TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

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1. scibot 29 Sep 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.stem.2023.07.001
  
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sciencedirect.com/science/article/pii/S1934590923002461
Jul 2023
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Title: TET1 Facilitates Specification of Early Human Lineages including Germ Cells

1
1. scibot 15 Jul 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.isci.2023.107191
  
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sciencedirect.com/science/article/pii/S2589004223012683
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Tet2 acts in the lateral habenula to regulate social preference in mice

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1. scibot 06 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112695
  
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sciencedirect.com/science/article/pii/S2211124723007064
Jun 2023
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Culture conditions of mouse ESCs impact the tumor appearance in vivo

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1. scibot 22 Jun 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2023.112645
  
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sciencedirect.com/science/article/pii/S2211124723006563
May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

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1. scibot 20 May 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.cell.2023.04.035
  
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sciencedirect.com/science/article/pii/S0092867423004695
Feb 2023
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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

1
1. scibot 03 Feb 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.ccell.2023.01.003
  
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sciencedirect.com/science/article/pii/S153561082300003X
Jan 2023
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Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia

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1. scibot 24 Jan 2023
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2023.112027
  
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sciencedirect.com/science/article/pii/S2211124723000384
Nov 2022
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Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

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1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111612
  
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sciencedirect.com/science/article/pii/S2211124722014814
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma

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1. scibot 02 Sep 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1077
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
Aug 2022
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The intrinsic and extrinsic effects of TET proteins during gastrulation

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1. scibot 02 Aug 2022
  
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  DOI: 10.1016/j.cell.2022.06.049
  
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sciencedirect.com/science/article/pii/S009286742200842X
Jul 2022
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Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle

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1. scibot 30 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111105
  
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sciencedirect.com/science/article/pii/S221112472200907X
Jun 2022
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A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

1
1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110928
  
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sciencedirect.com/science/article/pii/S2211124722007100
Mar 2022
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dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region

1
1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110457
  
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sciencedirect.com/science/article/pii/S221112472200184X
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8C-like cells capture the human zygotic genome activation program in vitro

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1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.stem.2022.01.014
  
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sciencedirect.com/science/article/pii/S1934590922000509
Jan 2022
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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

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1. scibot 26 Jan 2022
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2021.110253
  
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sciencedirect.com/science/article/pii/S2211124721017654
Nov 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia

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1. scibot 30 Nov 2021
  
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  RRID:AB_10013602
  
  DOI: 10.1111/jcmm.17060
  
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onlinelibrary.wiley.com/doi/10.1111/jcmm.17060
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Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring

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1. scibot 03 Nov 2021
  
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  RRID:AB_10013602
  
  DOI: 10.1016/j.celrep.2021.109912
  
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sciencedirect.com/science/article/pii/S2211124721013851
Aug 2021
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Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ

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TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice

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Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

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Glutamine Metabolism Controls Chondrocyte Identity and Function

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Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health

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5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease

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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

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Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency

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Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro‐myelinating genes

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TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition

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Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway

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Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

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Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

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Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis

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RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability

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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

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R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

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A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming

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Epigenetic Effects of an Adenosine Derivative in a Wistar Rat Model of Liver Cirrhosis

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Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ

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An Intrinsic Epigenetic Barrier for Functional Axon Regeneration

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A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming

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