84 Matching Annotations
  1. Last 7 days
  2. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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    sciencedirect.com/science/article/pii/S1535610824001314
  4. Apr 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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      DOI: 10.7554/eLife.94265

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
  6. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
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    1. scibot 19 Apr 2024
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      DOI: 10.1158/0008-5472.CAN-23-0910

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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  7. Mar 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pip5k1γ regulates axon formation by limiting Rap1 activity
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    1. scibot 07 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10912816/
  9. Feb 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  11. Jan 2024
  12. www.jneurosci.org www.jneurosci.org
    Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord
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    1. scibot 11 Jan 2024
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      DOI: 10.1523/JNEUROSCI.2206-21.2023

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    jneurosci.org/content/43/39/6592
  13. Dec 2023
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    EFNB1 levels determine distinct drug response patterns guiding precision therapy for B-cell neoplasms
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    sciencedirect.com/science/article/pii/S258900422302744X
  15. Oct 2023
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
    1
    1. scibot 27 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012822
  17. www.nature.com www.nature.com
    RhoA balances microglial reactivity and survival during neuroinflammation
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    1. scibot 21 Oct 2023
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    nature.com/articles/s41419-023-06217-w
  18. Aug 2023
  19. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    sciencedirect.com/science/article/pii/S1097276523005580
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    Targeting CD36 determines nicotine derivative NNK-induced lung adenocarcinoma carcinogenesis
    1
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
    1
    1. scibot 01 Aug 2023
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  22. Jul 2023
  23. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    2
    1. scibot 18 Jul 2023
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  24. Jun 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating FcγR function depends on endosomal-signaling platforms
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285637/
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    Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
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    sciencedirect.com/science/article/pii/S1097276523003325
  27. May 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
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    sciencedirect.com/science/article/pii/S2211124723005016
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  30. Mar 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035898/
  32. Feb 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    sciencedirect.com/science/article/pii/S1550413123000116
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    sciencedirect.com/science/article/pii/S1534580723000370
  35. Jan 2023
  36. www.sciencedirect.com www.sciencedirect.com
    CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance
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    sciencedirect.com/science/article/pii/S2666379123000022
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    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
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    sciencedirect.com/science/article/pii/S2211124723000086
  38. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16007
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
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      DOI: 10.1158/1535-7163.MCT-21-0964

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    A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration
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    sciencedirect.com/science/article/pii/S1534580722008498
  41. Oct 2022
  42. www.nature.com www.nature.com
    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
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      DOI: 10.1038/s41419-022-05318-2

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    nature.com/articles/s41419-022-05318-2
  43. Sep 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
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    sciencedirect.com/science/article/pii/S221112472201227X
  45. Jul 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis
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      DOI: 10.1016/j.stem.2022.06.004

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    sciencedirect.com/science/article/pii/S1934590922002533
  47. Jun 2022
  48. www.sciencedirect.com www.sciencedirect.com
    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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    sciencedirect.com/science/article/pii/S2211124722008087
  49. May 2022
  50. aacrjournals.org aacrjournals.org
    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
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      DOI: 10.1158/2159-8290.CD-21-1168

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    aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
  51. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  52. Feb 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822000058
  54. Jan 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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      DOI: 10.1016/j.immuni.2021.12.002

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    sciencedirect.com/science/article/pii/S1074761321005355
  56. Dec 2021
  57. link.springer.com link.springer.com
    Synergy of epidermal growth factor (EGFR) and angiotensin II (AT1R) receptor determines composition and temporal pattern of transcriptome variation
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      DOI: 10.1007/s00018-021-04065-5

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    link.springer.com/article/10.1007/s00018-021-04065-5
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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      DOI: 10.1016/j.isci.2021.103442

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633986/
  59. Nov 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124721015424
  61. Oct 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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      DOI: 10.1016/j.ebiom.2021.103617

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    ncbi.nlm.nih.gov/pmc/articles/PMC8517284/
  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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  64. www.sciencedirect.com www.sciencedirect.com
    Biosensors based on peptide exposure show single molecule conformations in live cells
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  65. Sep 2021
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    SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages
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  67. Aug 2021
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    RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of the firing activity by PKA‐PKC‐Src family kinases in cultured neurons of hypothalamic arcuate nucleus
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD36 initiates the secretory phenotype during the establishment of cellular senescence
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src
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      DOI: 10.3389/fnmol.2018.00344

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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase
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      DOI: 10.1523/JNEUROSCI.2519-16.2017

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  74. Jul 2021
  75. www.sciencedirect.com www.sciencedirect.com
    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
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  76. Jun 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Roles of adenosine A1 receptors in the regulation of SFK activity in the rat forebrain
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  78. www.sciencedirect.com www.sciencedirect.com
    Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
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    Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis
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  80. May 2021
  81. journals.plos.org journals.plos.org
    The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
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    Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
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  83. Feb 2021
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of the firing activity by PKA‐PKC‐Src family kinases in cultured neurons of hypothalamic arcuate nucleus
    1
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  85. Jan 2021
  86. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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  87. Nov 2020
  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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  89. Sep 2020
  90. www.sciencedirect.com www.sciencedirect.com
    Linkage of Non-receptor Tyrosine Kinase Fyn to mGlu5 Receptors in Striatal Neurons in a Depression Model
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  91. www.cell.com www.cell.com
    Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer
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      DOI: 10.1016/j.ccell.2019.12.012

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    cell.com/cancer-cell/abstract/S1535-6108(19)30582-3
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    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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  93. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer
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      DOI: 10.1016/j.ebiom.2020.102988

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  94. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
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      DOI: 10.1016/j.stem.2020.04.001

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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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  96. www.nature.com www.nature.com
    Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients
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      DOI: 10.1038/s12276-020-0413-1

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  97. www.sciencedirect.com www.sciencedirect.com
    Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway
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  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
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      DOI: 10.1111/jnc.14960

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  99. www.sciencedirect.com www.sciencedirect.com
    c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3
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  100. www.sciencedirect.com www.sciencedirect.com
    PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation
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  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
    1
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      Y416 phospho‐Src family

      DOI: 10.1002/ijc.32955

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  102. link.springer.com link.springer.com
    Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis
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      p-Src(Tyr416)

      DOI: 10.1186/s12885-020-07203-7

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  103. Jan 2020
  104. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐ angiogenesis effects via targeting VEGFR‐2 signaling
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      RRID:AB_10013641

      DOI: 10.1111/bph.14813

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  105. www.sciencedirect.com www.sciencedirect.com
    Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
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      DOI: 10.1016/j.ccell.2019.05.003

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    sciencedirect.com/science/article/pii/S1535610819302417
  106. www.sciencedirect.com www.sciencedirect.com
    Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
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      RRID:AB_10013641

      DOI: 10.1016/j.celrep.2019.11.036

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    sciencedirect.com/science/article/pii/S2211124719315189
  107. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of the firing activity by PKA‐PKC‐Src family kinases in cultured neurons of hypothalamic arcuate nucleus
    1
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      RRID:AB_10860257

      DOI: 10.1002/jnr.24516

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  108. www.sciencedirect.com www.sciencedirect.com
    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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      RRID:AB_10013641

      DOI: 10.1016/j.celrep.2019.09.047

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    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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      DOI: 10.1016/j.ccell.2019.08.006

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    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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      RRID:AB_10013641

      DOI: 10.1016/j.ccell.2018.10.001

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    sciencedirect.com/science/article/pii/S1535610818304677
  111. www.sciencedirect.com www.sciencedirect.com
    Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression
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      RRID:AB_10013641

      DOI: 10.1016/j.ebiom.2019.02.015

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    sciencedirect.com/science/article/pii/S2352396419300878
  112. www.jneurosci.org www.jneurosci.org
    Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss
    1
    1. scibot 13 Jan 2020
      RRID:AB_10013641

      DOI: 10.1523/JNEUROSCI.2983-18.2018

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    jneurosci.org/content/39/10/1910
  113. Nov 2018
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src
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    1. scibot 05 Nov 2018
      RRID: AB_10013641

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6172853/
  115. www.sciencedirect.com www.sciencedirect.com
    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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  116. Nov 2017
  117. www.sciencedirect.com www.sciencedirect.com
    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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      AB_10013641

      Curator: @chewbeccax

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  118. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dopamine D2 receptors are involved in the regulation of fyn and metabotropic glutamate receptor 5 phosphorylation in the rat striatum in vivo
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      Curator: @jcabotaj

      Curator note: table

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23713/full