319 Matching Annotations
  1. Last 7 days
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    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    sciencedirect.com/science/article/pii/S0092867424012005
  3. Oct 2024
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    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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  5. Sep 2024
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    A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation
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    CATP-8/P5A ATPase Regulates ER Processing of the DMA-1 Receptor for Dendritic Branching
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    Dynamic allostery drives autocrine and paracrine TGF-β signaling
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  9. Aug 2024
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    The conformational plasticity of structurally unrelated lipid transport proteins correlates with their mode of action
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    ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes
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    Impact of aging on the GABAB receptor-mediated connectome
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  13. 52.53.155.43 52.53.155.43
    PMC10174194 S1 Table-html.html
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    EphA4 has distinct functionality from EphA7 in the corticothalamic system during mouse brain development
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    Immunohistochemical localization of DPP10 in rat brain supports the existence of a Kv4/KChIP/DPPL ternary complex in neurons
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  16. Jul 2024
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    TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
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    Intracellular tau fragment droplets serve as seeds for tau fibrils
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    Patterning in stratified epithelia depends on cell–cell adhesion
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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    Competition between two HUSH complexes orchestrates the immune response to retroelement invasion
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    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    PIIS2589004224017000-html.html
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    Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue
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  25. Jun 2024
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    Evolution of paralogous multicomponent systems for site-specific O-sialylation of flagellin in Gram-negative and Gram-positive bacteria
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  27. May 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ventromedial Hypothalamic Nucleus Subset Stimulates Tissue Thermogenesis via Preoptic Area Outputs
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    Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer
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    The brain-specific kinase LMTK3 regulates neuronal excitability by decreasing KCC2-dependent neuronal Cl− extrusion
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    PDZD8 promotes autophagy at ER-Lysosome contact sites to regulate synaptogenesis
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    Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness
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  33. Apr 2024
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    JNEUROSCI.1563-23.2024.full (1)-html.html
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    Association of DNA methylation/demethylation with the functional outcome of stroke in a hyperinflammatory state
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  36. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
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    Molecular basis for pH sensing in the KDEL trafficking receptor
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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      DOI: 10.7554/eLife.96891

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  39. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass and adipose metabolism for the promotion of thermogenesis
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  41. Mar 2024
  42. www.sciencedirect.com www.sciencedirect.com
    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
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    sciencedirect.com/science/article/pii/S2211124724003322
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951324/
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    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    A humoral stress response protects Drosophila tissues from antimicrobial peptides
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    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
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  47. Feb 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID
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    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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  88. May 2023
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    Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
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    BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses
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  95. Apr 2023
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    Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains
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    A tissue injury sensing and repair pathway distinct from host pathogen defense
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    Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors
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      DOI: 10.1210/clinem/dgad136

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    Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
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    Conformational dynamics of lipid transfer domains provide a general framework to decode their functional mechanism
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    X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species
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    Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration
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  103. Mar 2023
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    Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients
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  105. Feb 2023
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    Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
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    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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    TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions
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  109. Jan 2023
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    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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    Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication
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    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
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    Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant
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    Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
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  117. Dec 2022
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    β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models
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    Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila
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  121. Nov 2022
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    MPS1 localizes to end-on microtubule-attached kinetochores to promote microtubule release
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    Monitoring fusion kinetics of viral and target cell membranes in living cells using a SARS-CoV-2 spike protein-mediated membrane fusion assay
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    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
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  125. Oct 2022
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    K+ channel Kv4.1 is expressed in the nociceptors/secondary nociceptive neurons and participates in pain regulation
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    Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress
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  128. www.science.org www.science.org
    Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity
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      DOI: 10.1126/sciadv.abq8678

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    Role for <i>N</i>-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity.
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  130. Aug 2022
  131. www.sciencedirect.com www.sciencedirect.com
    Non-degradable autophagic vacuoles are indispensable for cell competition
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    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
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    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
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    Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues
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  136. www.sciencedirect.com www.sciencedirect.com
    Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
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  137. Jul 2022
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor
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    Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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  142. Jun 2022
  143. www.sciencedirect.com www.sciencedirect.com
    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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    Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion
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    Pten heterozygosity restores neuronal morphology in fragile X syndrome mice
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  146. May 2022
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    Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males
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    A TLR4-independent critical role for CD14 in intracellular LPS sensing
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    Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells
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    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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  153. Apr 2022
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    Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells
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    Characterization and functional interrogation of the SARS-CoV-2 RNA interactome
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    GABAA and Glycine Receptor-Mediated Inhibitory Synaptic Transmission onto Adult Rat Lamina IIi PKC&gamma;-Interneurons: Pharmacological but Not Anatomical Specialization
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    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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    Functional elements of the cis-regulatory lincRNA-p21
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    Extracellular ATP facilitates cell extrusion from epithelial layers mediated by cell competition or apoptosis
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  160. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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  161. Mar 2022
  162. www.sciencedirect.com www.sciencedirect.com
    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts
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    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
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  165. Feb 2022
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    Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion
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    Silencing of hippocampal somatostatin interneurons induces recurrent spontaneous limbic seizures in mice
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    Heat shock induces premature transcript termination and reconfigures the human transcriptome
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    βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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    A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells
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  172. Jan 2022
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    E3 Ubiquitin Ligase Nedd4-2 Exerts Neuroprotective Effects During Endoplasmic Reticulum Stress
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  174. Dec 2021
  175. www.sciencedirect.com www.sciencedirect.com
    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila
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  177. Nov 2021
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    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
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    A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
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  180. Oct 2021
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    P5A ATPase controls ER translocation of Wnt in neuronal migration
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    Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity
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  183. Sep 2021
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    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
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  185. elifesciences.org elifesciences.org
    The amyloid precursor protein is a conserved Wnt receptor
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    Neuroimmunological complications arising from chemotherapy-induced gut toxicity and opioid exposure in female dark agouti rats
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    Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in Pten Haploinsufficient Mice
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      DOI: 10.3390/genes12091366

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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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  190. Aug 2021
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    Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed
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      DOI: 10.1016/j.neuron.2021.07.006

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  192. elifesciences.org elifesciences.org
    The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules
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      DOI: 10.7554/eLife.67294

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    The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes
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    VEGF/VEGFR2 signaling regulates hippocampal axon branching during development
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    Brain mapping of the gonadotropin‐inhibitory hormone‐related peptide 2 with a novel antibody suggests a connection with emotional reactivity in the Japanese quail (Coturnix japonica, Temminck & Schlegel, 1849)
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    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Pharmacological inhibition of Vanin-1 is not protective in models of acute and chronic kidney disease
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
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    Changes in testicular gene expression following reduced estradiol synthesis: a complex pathway to increased porcine Sertoli cell proliferation‡
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    Secretion Relieves Translational Co-repression by a Specialized Flagellin Paralog
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    Profiling of microRNA targets using activity-based protein profiling: linking enzyme activity to microRNA-185 function
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    CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
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    Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease
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    sciencedirect.com/science/article/pii/S1534580721003105
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    1. scibot 21 Apr 2021
      RRID:AB_10015282

      DOI: 10.1016/j.celrep.2021.109012

      Resource: (Jackson ImmunoResearch Labs Cat# 711-035-152, RRID:AB_10015282)

      Curator: @Naa003

      SciCrunch record: RRID:AB_10015282

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      RRIDCUR:Validated RRID:AB_10015282
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    sciencedirect.com/science/article/pii/S2211124721003260
  236. www.sciencedirect.com www.sciencedirect.com
    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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    1. scibot 17 Apr 2021
      RRID:AB_10015282

      DOI: 10.1016/j.ccell.2020.05.005

      Resource: (Jackson ImmunoResearch Labs Cat# 711-035-152, RRID:AB_10015282)

      Curator: @Naa003

      SciCrunch record: RRID:AB_10015282

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      RRID:AB_10015282 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820302555
  237. www.cell.com www.cell.com
    The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface
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    1. scibot 08 Apr 2021
      RRID:AB_10015282

      DOI: 10.1016/j.cub.2021.02.039

      Resource: (Jackson ImmunoResearch Labs Cat# 711-035-152, RRID:AB_10015282)

      Curator: @evieth

      SciCrunch record: RRID:AB_10015282

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      RRIDCUR:Validated RRID:AB_10015282
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    cell.com/current-biology/abstract/S0960-9822(21)00283-9