36 Matching Annotations
  1. Oct 2024
  2. www.nature.com www.nature.com
    QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
    1
    1. scibot 01 Oct 2024
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      DOI: 10.1038/s41467-024-52587-w

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    nature.com/articles/s41467-024-52587-w
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
    1
    1. scibot 18 Sep 2024
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      DOI: 10.1038/s41523-024-00687-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.devcel.2024.08.003

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    sciencedirect.com/science/article/pii/S1534580724004866
  7. Jul 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
    1
    1. scibot 24 Jul 2024
      AB_10544692

      DOI: 10.1016/j.immuni.2024.05.025

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    sciencedirect.com/science/article/pii/S1074761324002796
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101645

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.isci.2024.110137

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    ncbi.nlm.nih.gov/pmc/articles/PMC11246000/
  11. Apr 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101526

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    sciencedirect.com/science/article/pii/S2666379124001952
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
    1
    1. scibot 06 Mar 2024
      RRID:AB_10544692

      DOI: 10.1016/j.celrep.2023.113661

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851928/
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
    1
    1. scibot 16 Dec 2023
      RRID:AB_10548756

      DOI: 10.1016/j.celrep.2023.113564

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    sciencedirect.com/science/article/pii/S2211124723015760
  17. Nov 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia
    1
    1. scibot 28 Nov 2023
      RRID:AB_10544692

      DOI: 10.1016/j.biopha.2023.115905

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    sciencedirect.com/science/article/pii/S0753332223017031
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
    2
    1. scibot 11 Nov 2023
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      DOI: 10.1097/BS9.0000000000000168

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    2. scibot 11 Nov 2023
      RRID:AB_10544692

      DOI: 10.1097/BS9.0000000000000168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  20. Aug 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
    1
    1. scibot 04 Aug 2023
      RRID:AB_10544692

      DOI: 10.1016/j.isci.2023.107369

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    ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
  22. Jul 2023
  23. www.nature.com www.nature.com
    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
    1
    1. scibot 15 Jul 2023
      RRID:AB_10544692

      DOI: 10.1038/s41467-023-39715-8

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    nature.com/articles/s41467-023-39715-8
  24. Jun 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis
    1
    1. scibot 08 Jun 2023
      RRID:AB_10544692

      DOI: 10.1016/j.isci.2023.106924

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    ncbi.nlm.nih.gov/pmc/articles/PMC10239700/
  26. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.007

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    sciencedirect.com/science/article/pii/S2451945623001502
  27. May 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
    1
    1. scibot 10 May 2023
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      DOI: 10.1016/j.celrep.2023.112490

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    sciencedirect.com/science/article/pii/S2211124723005016
  29. academic.oup.com academic.oup.com
    Characterisation of dominant-negative GH receptor variants reveals a potential therapeutic target for short stature
    1
    1. scibot 04 May 2023
      RRID:AB_10544692

      DOI: 10.1093/ejendo/lvad039

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    academic.oup.com/ejendo/article/188/4/353/7082475
  30. Mar 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes
    1
    1. scibot 16 Mar 2023
      RRID:AB_10544692

      DOI: 10.1158/2767-9764.CRC-22-0368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10010194/
  32. Nov 2022
  33. academic.oup.com academic.oup.com
    Ketone Body Infusion abrogates Growth Hormone Induced Lipolysis and Insulin Resistance
    1
    1. scibot 18 Nov 2022
      RRID:AB_10544692

      DOI: 10.1210/clinem/dgac595

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac595/6761325
  34. Sep 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
    1
    1. scibot 02 Sep 2022
      RRID:AB_10544692

      DOI: 10.1158/2159-8290.CD-21-0694

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  36. Jul 2022
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma
    1
    1. scibot 12 Jul 2022
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      DOI: 10.1002/ctm2.939

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    onlinelibrary.wiley.com/doi/10.1002/ctm2.939
  38. Apr 2022
  39. www.sciencedirect.com www.sciencedirect.com
    HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells
    1
    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110650

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    sciencedirect.com/science/article/pii/S2211124722004028
  40. Dec 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
    1
    1. scibot 15 Dec 2021
      RRID:AB_10548756

      DOI: 10.1016/j.celrep.2021.110068

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    sciencedirect.com/science/article/pii/S2211124721015540
  42. Sep 2021
  43. academic.oup.com academic.oup.com
    Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity
    1
    1. scibot 04 Sep 2021
      RRID:AB_10544692

      DOI: 10.1210/clinem/dgab550

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab550/6329461
  44. www.sciencedirect.com www.sciencedirect.com
    Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming
    1
    1. scibot 01 Sep 2021
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      DOI: 10.1016/j.immuni.2021.05.005

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    sciencedirect.com/science/article/pii/S1074761321002119
  45. Jul 2021
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis
    1
    1. scibot 27 Jul 2021
      RRID:AB_10544692

      DOI: 10.1096/fj.201901718RR

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      Curator comments: Phospho-Stat5 (Tyr694) (D47E7) XP Rabbit mAb antibody Cell Signaling Technology Cat# 4322

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    onlinelibrary.wiley.com/doi/10.1096/fj.201901718RR
  47. May 2021
  48. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
    1
    1. scibot 10 May 2021
      RRID:AB_10544692

      DOI: 10.1210/clinem/dgaa893

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    academic.oup.com/jcem/article/106/3/718/6009067
  49. Feb 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models
    1
    1. scibot 27 Feb 2021
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      DOI: 10.1371/journal.pone.0231877

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    ncbi.nlm.nih.gov/pmc/articles/PMC7313537/
  51. Nov 2020
  52. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
    1
    1. scibot 07 Nov 2020
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      DOI: 10.1016/j.celrep.2020.108333

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    sciencedirect.com/science/article/pii/S221112472031322X
  53. Oct 2020
  54. www.cell.com www.cell.com
    Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
    1
    1. scibot 16 Oct 2020
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      DOI: 10.1016/j.stem.2020.05.008

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    cell.com/cell-stem-cell/abstract/S1934-5909(20)30206-X
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
    1
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      DOI: 10.1016/j.celrep.2020.108158

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    sciencedirect.com/science/article/pii/S2211124720311475
  57. Jan 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
    1
    1. scibot 13 Jan 2020
      RRID:AB_10544692

      DOI: 10.1016/j.cmet.2019.10.015

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    sciencedirect.com/science/article/pii/S1550413119306060
  59. www.sciencedirect.com www.sciencedirect.com
    Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.09.035

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    sciencedirect.com/science/article/pii/S2211124719312239
  60. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
    1
    1. scibot 13 Jan 2020
      RRID:AB_10544692

      DOI: 10.1016/j.ccell.2019.10.002

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    sciencedirect.com/science/article/pii/S1535610819304763
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.05.020

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    sciencedirect.com/science/article/pii/S221112471930631X