38 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
    1
    1. scibot 16 Nov 2024
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      DOI: 10.1016/j.cell.2024.10.010

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    sciencedirect.com/science/article/pii/S0092867424011589
  3. www.sciencedirect.com www.sciencedirect.com
    Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis
    1
    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.celrep.2024.114966

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    sciencedirect.com/science/article/pii/S2211124724013172
  4. Jul 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An immunohistochemical atlas of necroptotic pathway expression
    1
    1. scibot 18 Jul 2024
      RRID:AB_10545768

      DOI: 10.1038/s44321-024-00074-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11250867/
  6. www.cell.com www.cell.com
    Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis
    1
    1. scibot 12 Jul 2024
      RRID:AB_10545768

      DOI: 10.1016/j.celrep.2024.114453

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    cell.com/cell-reports/fulltext/S2211-1247(24)00782-4
  7. Jun 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interaction between RIPK1 and FADD controls perinatal lethality and inflammation
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114335

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    ncbi.nlm.nih.gov/pmc/articles/PMC11256114/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
    1
    1. scibot 03 Jun 2024
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      DOI: 10.1016/j.isci.2024.109983

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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  10. May 2024
  11. www.sciencedirect.com www.sciencedirect.com
    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.04.016

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    sciencedirect.com/science/article/pii/S1074761324002218
  12. Apr 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
    1
    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S0006295224001813
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114004

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    sciencedirect.com/science/article/pii/S2211124724003322
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113581

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    sciencedirect.com/science/article/pii/S2211124723015930
  18. www.sciencedirect.com www.sciencedirect.com
    Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death
    1
    1. scibot 02 Dec 2023
      RRID:AB_10545768

      DOI: 10.1016/j.celrep.2023.113513

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    sciencedirect.com/science/article/pii/S2211124723015255
  19. Nov 2023
  20. www.biorxiv.org www.biorxiv.org
    An immunohistochemical atlas of necroptotic pathway expression
    1
    1. scibot 10 Nov 2023
      RRID:AB_10545768

      DOI: 10.1101/2023.10.31.565039

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    biorxiv.org/content/10.1101/2023.10.31.565039v1
  21. Aug 2023
  22. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
  23. Jun 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.039

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    sciencedirect.com/science/article/pii/S0092867423005913
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112008

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    sciencedirect.com/science/article/pii/S2211124723000190
  27. www.sciencedirect.com www.sciencedirect.com
    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111961

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    sciencedirect.com/science/article/pii/S2211124722018654
  28. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 14 Jan 2023
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      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  29. www.sciencedirect.com www.sciencedirect.com
    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
    1
    1. scibot 04 Jan 2023
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      DOI: 10.1016/j.str.2022.12.002

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    sciencedirect.com/science/article/pii/S0969212622004889
  30. Dec 2022
  31. www.science.org www.science.org
    Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies
    1
    1. scibot 24 Dec 2022
      RRID:AB_10545768

      DOI: 10.1126/scisignal.abl6781

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    science.org/doi/10.1126/scisignal.abl6781
  32. Nov 2022
  33. www.science.org www.science.org
    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
    1
    1. scibot 12 Nov 2022
      RRID:AB_10545768

      DOI: 10.1126/scisignal.abi8713

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    science.org/doi/10.1126/scisignal.abi8713
  34. Jul 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells
    1
    1. scibot 09 Jul 2022
      RRID:AB_10545768

      DOI: 10.7554/eLife.74443

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262386/
  36. Jun 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
    1
    1. scibot 25 Jun 2022
      RRID:AB_10545768

      DOI: 10.1016/j.isci.2022.104518

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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  38. www.sciencedirect.com www.sciencedirect.com
    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
    1
    1. scibot 22 Jun 2022
      RRID:AB_10545768

      DOI: 10.1016/j.isci.2022.104527

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    sciencedirect.com/science/article/pii/S2589004222007982
  39. academic.oup.com academic.oup.com
    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
    1
    1. scibot 02 Jun 2022
      AB_10545768

      DOI: 10.1210/endocr/bqac048

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    academic.oup.com/endo/article/163/6/bqac048/6569208
  40. Feb 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
    1
    1. scibot 05 Feb 2022
      RRID: AB_10545768

      DOI: 10.21037/tcr-20-1677

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    ncbi.nlm.nih.gov/pmc/articles/PMC8797319/
  42. Nov 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103256

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    sciencedirect.com/science/article/pii/S2589004221012256
  44. Aug 2021
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
    1
    1. scibot 17 Aug 2021
      RRID:AB_10545768

      DOI: 10.1158/1078-0432.CCR-18-3683

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    ncbi.nlm.nih.gov/pmc/articles/PMC7887036/
  46. Jun 2021
  47. elifesciences.org elifesciences.org
    Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis
    1
    1. scibot 17 Jun 2021
      RRID:AB_10545768

      DOI: 10.7554/eLife.58342

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    elifesciences.org/articles/58342
  48. May 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
    1
    1. scibot 12 May 2021
      RRID:AB_10545768

      DOI: 10.1016/j.immuni.2021.04.012

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    sciencedirect.com/science/article/pii/S1074761321001746
  50. www.sciencedirect.com www.sciencedirect.com
    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
    1
    1. scibot 07 May 2021
      RRID:AB_10545768

      DOI: 10.1016/j.molcel.2020.09.004

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    sciencedirect.com/science/article/pii/S1097276520306122
  51. www.sciencedirect.com www.sciencedirect.com
    Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
    1
    1. scibot 06 May 2021
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      DOI: 10.1016/j.immuni.2020.04.010

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    sciencedirect.com/science/article/pii/S1074761320301680
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.017

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    sciencedirect.com/science/article/pii/S1550413120305507
  54. www.sciencedirect.com www.sciencedirect.com
    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
    1
    1. scibot 14 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108998

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    sciencedirect.com/science/article/pii/S2211124721003120
  55. Jan 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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      DOI: 10.1016/j.cell.2019.06.014

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    sciencedirect.com/science/article/pii/S0092867419306774
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fluoxetine and its metabolite norfluoxetine induce microglial apoptosis
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1111/jnc.14661

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14661
  58. Nov 2018
  59. www.sciencedirect.com www.sciencedirect.com
    Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death
    1
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    sciencedirect.com/science/article/pii/S2451945618301855
  60. Nov 2017
  61. www.sciencedirect.com www.sciencedirect.com
    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S2451945617300922