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  1. Last 7 days
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    STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts
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    sciencedirect.com:5037/science/article/pii/S2211124725014755
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695159/
  5. Jun 2025
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    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    sciencedirect.com/science/article/pii/S2451945625001667
  7. May 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
  9. Nov 2024
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    High fat diet induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550620/
  11. Oct 2024
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    Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10545554/
  13. Sep 2024
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    Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway
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    sciencedirect.com/science/article/pii/S2211124724010970
  15. Jan 2024
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    science.org/doi/10.1126/scisignal.adg5289
  17. Jul 2023
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    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  19. Jan 2023
  20. academic.oup.com academic.oup.com
    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
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    academic.oup.com/endo/article/164/3/bqac214/6969391
  21. Dec 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
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    sciencedirect.com/science/article/pii/S1550413122005034
  23. May 2022
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    Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment
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    link.springer.com/article/10.1186/s40478-022-01352-5
  25. Jan 2022
  26. 52.53.155.43 52.53.155.43
    en.2019-00132-html.html
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  27. Jul 2021
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of candidates for driver oncogenes in scirrhous‐type gastric cancer cell lines
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    onlinelibrary.wiley.com/doi/full/10.1111/cas.14111
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5761602/
  30. Apr 2021
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    Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference
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    sciencedirect.com/science/article/pii/S1550413120304861
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    A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance
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    sciencedirect.com/science/article/pii/S1550413120304149
  33. Feb 2021
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    CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
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    sciencedirect.com/science/article/pii/S2211124721000814
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    Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes
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    sciencedirect.com/science/article/pii/S2211124721000425
  36. Sep 2020
  37. dev.biologists.org dev.biologists.org
    Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis
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    dev.biologists.org/content/147/11/dev190488
  38. Nov 2018
  39. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
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    sciencedirect.com/science/article/pii/S1535610818303696
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    academic.oup.com/endo/article/159/1/285/4259053