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    Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
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    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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  5. 52.53.155.43 52.53.155.43
    elife-90523-v1-html.html
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    Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation
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  7. Apr 2024
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    Time-series reconstruction of the molecular architecture of human centriole assembly
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    Decreases in the number of microglia and neural circuit dysfunction elicited by developmental exposure to neonicotinoid pesticides in mice
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    GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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  12. Mar 2024
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    New genetic tools for mushroom body output neurons in Drosophila
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    Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation
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    Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
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    Generation of induced pluripotent stem cells (UCLi024-A) from a patient with argininosuccinate lyase deficiency carrying a homozygous c.437G > A (p.Arg146Gln) mutation
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    Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line
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    Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response
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    sciencedirect.com/science/article/pii/S0960982224001568
  19. Feb 2024
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury
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    Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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  25. Jan 2024
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    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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    Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system
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    KMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans
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      DOI: 10.3390/genes15010048

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth
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  30. Dec 2023
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    Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation
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    Maternal separation early in life induces excessive activity of the central amygdala related to abnormal aggression
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      DOI: 10.1111/jnc.16020

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    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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    Nutrient-regulated control of lysosome function by signaling lipid conversion
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      DOI: 10.1016/j.cell.2023.09.027

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  35. www.biorxiv.org www.biorxiv.org
    Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line
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      DOI: 10.1101/2023.11.20.567945

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    biorxiv.org/content/10.1101/2023.11.20.567945v1
  36. Nov 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Disruptions in cell fate decisions and transformed enteroendocrine cells drive intestinal tumorigenesis in Drosophila
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  38. www.cell.com www.cell.com
    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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    cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    Impact of Heat and Cold Shock on Epigenetics and Chromatin Structure
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      DOI: 10.1016/j.ejcb.2023.151373

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    Generation of induced pluripotent stem cell line (TMOi001-A-11) carrying a homozygous deletion in the synemin gene using CRISPR/Cas9
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    sciencedirect.com/science/article/pii/S1873506123002404
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    Stress-induced β cell early senescence confers protection against type 1 diabetes
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  43. Oct 2023
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    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
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    Neural circuit mechanisms for transforming learned olfactory valences into wind-oriented movement
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      DOI: 10.7554/eLife.85756

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification
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  47. www.biorxiv.org www.biorxiv.org
    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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      DOI: 10.1101/2023.10.02.560011

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    Generation and characterization of induced pluripotent stem cells from a Parkinson’s disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    Typhoid toxin hijacks Wnt5a to establish host senescence and Salmonella infection
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
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    Neuronal activity drives IGF2 expression from pericytes to form long-term memory
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  53. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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  54. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
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      DOI: 10.15252/embj.2023114032

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  55. Sep 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hunger- and thirst-sensing neurons modulate a neuroendocrine network to coordinate sugar and water ingestion
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  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Salt-inducible kinases are required for glucose uptake and insulin signaling in human adipocytes
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout
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  59. www.embopress.org www.embopress.org
    Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease
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  60. Aug 2023
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    Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
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    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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  63. Jul 2023
  64. www.sciencedirect.com www.sciencedirect.com
    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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  66. 52.53.155.43 52.53.155.43
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice
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  68. Jun 2023
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    Protocol to analyze endogenous translesion DNA synthesis in single mammalian cells
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    Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3
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    Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
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    Input density tunes Kenyon cell sensory responses in the Drosophila mushroom body
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    Detection of endogenous translesion DNA synthesis in single mammalian cells
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    Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
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  77. www.science.org www.science.org
    Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification
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  78. May 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Compartmentalization of soluble endocytic proteins in synaptic vesicle clusters by phase separation
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  80. academic.oup.com academic.oup.com
    FriendlyClearMap: an optimized toolkit for mouse brain mapping and analysis
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila Tachykininergic Neurons Modulate the Activity of Two Groups of Receptor-Expressing Neurons to Regulate Aggressive Tone
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      DOI: 10.1523/JNEUROSCI.1734-22.2023

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  82. Apr 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
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    A tubule-sheet continuum model for the mechanism of nuclear envelope assembly
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    Thymidine kinase 1 drives hepatocellular carcinoma in enzyme-dependent and -independent manners
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    Optineurin provides a mitophagy contact site for TBK1 activation
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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      DOI: 10.7554/eLife.78629

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Extracellular matrix protein anosmin-1 overexpression alters dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in a MPTP model of Parkinson’s disease
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    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A>G (p.T351A) or c.2067A>G (p.T610A) in the RHOT1 gene encoding Miro1
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    Social deprivation induces astrocytic TRPA1-GABA suppression of hippocampal circuits
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    Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression
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    D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase
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    Generation of glutamatergic/GABAergic neuronal co-cultures derived from human induced pluripotent stem cells for characterizing E/I balance in vitro
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    A high-throughput electron tomography workflow reveals over-elongated centrioles in relapsed/refractory multiple myeloma
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  130. Sep 2022
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    Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy
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    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
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    The NHE3 Inhibitor Tenapanor Prevents Intestinal Obstructions in CFTR-Deleted Mice
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    Tonotopic differentiation of presynaptic neurotransmitter-releasing machinery in the auditory brainstem during the prehearing period and its selective deficits in Fmr1 knockout mice
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays
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  137. Aug 2022
  138. www.sciencedirect.com www.sciencedirect.com
    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice
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    Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop
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    Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
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    A regulatory network of Sox and Six transcription factors initiate a cell fate transformation during hearing regeneration in adult zebrafish
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    Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
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    Improved Fluorescent Signal in Expansion Microscopy Using Fluorescent Fab Fragment Secondary Antibodies
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    Melanopsin retinal ganglion cells mediate light-promoted brain development
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  146. Jul 2022
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    An improved organotypic cell culture system to study tissue-resident macrophages ex vivo
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    Sox11b regulates the migration and fate determination of... : Neural Regeneration Research
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    Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
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  151. Jun 2022
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    Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy
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    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
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  154. aacrjournals.org aacrjournals.org
    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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    Effects of noise exposure and aging on behavioral tone detection in quiet and noise by mice
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    Interplay between symmetric arginine dimethylation and ubiquitylation regulates TDP1 proteostasis for the repair of topoisomerase I-DNA adducts
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    Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
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  158. elifesciences.org elifesciences.org
    Drosophila gustatory projections are segregated by taste modality and connectivity
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    Glioma progression is shaped by genetic evolution and microenvironment interactions
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  160. May 2022
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    Feedback from nuclear RNA on transcription promotes robust RNA concentration homeostasis in human cells
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    Glutamate released by Cajal-Retzius cells impacts specific hippocampal circuits and behaviors
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    Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson‘s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1)
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    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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  166. journals.plos.org journals.plos.org
    Vocal changes in a zebra finch model of Parkinson’s disease characterized by alpha-synuclein overexpression in the song-dedicated anterior forebrain pathway
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    Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
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  168. Apr 2022
  169. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of a genetic Parkinson‘s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A)
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    Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture
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    Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements
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    Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake
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  173. www.nature.com www.nature.com
    Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
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  174. Mar 2022
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    A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis
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    A local insulin reservoir in Drosophila alpha cell homologs ensures developmental progression under nutrient shortage
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  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subventricular zone neural precursor cell responses after traumatic brain injury and binge alcohol in male rats
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  178. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures
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  179. www.nature.com www.nature.com
    Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1G93A mice
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    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
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    Metabolic incorporation of electron-rich ribonucleosides enhances APEX-seq for profiling spatially restricted nascent transcriptome
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    Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters
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    Boar spermadhesin AWN: Novel insights in its binding behavior and localization on sperm
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    Generation of induced pluripotent stem cell lines carrying monoallelic (UCSFi001-A-60) or biallelic (UCSFi001-A-61; UCSFi001-A-62) frameshift variants in CACNA1A using CRISPR/Cas9
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    Differential dendritic integration of long-range inputs in association cortex via subcellular changes in synaptic AMPA-to-NMDA receptor ratio
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    C-type natriuretic peptide-induced PKA activation promotes endochondral bone formation in hypertrophic chondrocytes
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    Chlamydomonas ARMC2/PF27 is an obligate cargo adapter for intraflagellar transport of radial spokes
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    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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  194. Dec 2021
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  197. Nov 2021
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    Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
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    Identification and characterization of rostral ventromedial medulla (RVM) neurons synaptically connected to the urinary bladder afferents in female rats with or without neonatal cystitis
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    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
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    Individual bitter-sensing neurons in Drosophila exhibit both ON and OFF responses that influence synaptic plasticity
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  207. Oct 2021
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    An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury
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    Exocyst complex mediates recycling of internal cilia
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    Generation of DMBi002-A human induced pluripotent stem cell line from patient with Spinal Muscular Atrophy type 3
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    The hippocampus converts dynamic entorhinal inputs into stable spatial maps
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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  213. Sep 2021
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    The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons
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    Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
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    Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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    Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
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    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus
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    AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions
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  225. Aug 2021
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    Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections
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      RRID:AB_10563566

      DOI: 10.1016/j.celrep.2021.109614

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  227. rupress.org rupress.org
    zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways
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    1. scibot 12 Aug 2021
      10563566

      DOI: 10.1083/jcb.202103186

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  228. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_10563566

      DOI: 10.1002/cne.23779

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  229. elifesciences.org elifesciences.org
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      AB_10563566

      DOI: 10.7554/eLife.31326

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  230. www.sciencedirect.com www.sciencedirect.com
    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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    1. scibot 11 Aug 2021
      RRID:AB_10563566

      DOI: 10.1016/j.molcel.2017.09.024

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