63 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
  3. Aug 2024
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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    sciencedirect.com/science/article/pii/S2589004224017243
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    Sestrin2 drives ER-phagy in response to protein misfolding
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    sciencedirect.com/science/article/pii/S1534580724004416
  6. Jul 2024
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    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
    1
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      DOI: 10.3390/ijms25137168

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  8. Jun 2024
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    Short-term cold exposure induces persistent epigenomic memory in brown fat
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    sciencedirect.com/science/article/pii/S1550413124001876
  10. Apr 2024
  11. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
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      DOI: 10.1083/jcb.202307026

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  12. Feb 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
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    Specialized replication mechanisms maintain genome stability at human centromeres
    2
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    sciencedirect.com/science/article/pii/S1097276524000546
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
    1
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    CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome
    1
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  17. Nov 2023
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    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
    1
    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S1097276523008481
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
    1
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    sciencedirect.com/science/article/pii/S1097276521001787
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    Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function
    1
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      DOI: 10.1016/j.isci.2023.108151

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    sciencedirect.com/science/article/pii/S2589004223022289
  21. Oct 2023
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    GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study
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      DOI: 10.1016/j.ebiom.2023.104849

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    sciencedirect.com/science/article/pii/S2352396423004152
  23. Aug 2023
  24. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
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      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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  25. Jul 2023
  26. www.sciencedirect.com www.sciencedirect.com
    FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns
    1
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      DOI: 10.1016/j.molcel.2023.07.002

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    sciencedirect.com/science/article/pii/S1097276523005166
  27. Apr 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
    1
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      DOI: 10.7554/eLife.78629

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  29. Feb 2023
  30. www.sciencedirect.com www.sciencedirect.com
    PIMT regulates Hepatic Gluconeogenesis in Mice
    1
    1. scibot 25 Feb 2023
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      DOI: 10.1016/j.isci.2023.106120

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    sciencedirect.com/science/article/pii/S2589004223001979
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    DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
    1
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      DOI: 10.1016/j.celrep.2023.112148

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    sciencedirect.com/science/article/pii/S2211124723001596
  32. Nov 2022
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15971

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15971
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    Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
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      DOI: 10.1016/j.cell.2022.10.003

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    sciencedirect.com/science/article/pii/S0092867422013186
  35. Oct 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
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    sciencedirect.com/science/article/pii/S1534580722006323
  37. Aug 2022
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    Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
    1
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      DOI: 10.1016/j.devcel.2022.07.016

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    sciencedirect.com/science/article/pii/S1534580722005470
  39. Mar 2022
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    CENP-B-mediated DNA loops regulate activity and stability of human centromeres
    1
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    sciencedirect.com/science/article/pii/S1097276522002064
  41. Dec 2021
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    Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation
    1
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    sciencedirect.com/science/article/pii/S1550413121005313
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine deprivation triggers NAGK-dependent hexosamine salvage
    1
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      DOI: 10.7554/eLife.62644

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
  44. Nov 2021
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
    1
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      DOI: 10.7554/eLife.58313

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    ncbi.nlm.nih.gov/pmc/articles/PMC8547954/
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    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
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    sciencedirect.com/science/article/pii/S2211124721013978
  47. Oct 2021
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    Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
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    sciencedirect.com/science/article/pii/S2211124721012171
  49. Sep 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
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      DOI: 10.1038/s41598-021-96444-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
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    Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
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    sciencedirect.com/science/article/pii/S2211124721010354
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy
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    sciencedirect.com/science/article/pii/S2211124721010123
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.celrep.2019.01.105

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    ncbi.nlm.nih.gov/pmc/articles/PMC6391843/
  55. Jul 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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      DOI: 10.1016/j.cub.2019.07.052

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    sciencedirect.com/science/article/pii/S0960982219309327
  57. www.cell.com www.cell.com
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      DOI: 10.1016/j.cell.2017.09.015

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    cell.com/cell/abstract/S0092-8674(17)31064-4
  58. Jun 2021
  59. www.sciencedirect.com www.sciencedirect.com
    NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124721005970
  60. May 2021
  61. www.cell.com www.cell.com
    Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
    1
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  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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  64. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      DOI: 10.1016/j.ccell.2020.07.008

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  65. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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  66. Mar 2021
  67. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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      DOI: 10.1016/j.celrep.2021.108808

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  68. Nov 2020
  69. www.sciencedirect.com www.sciencedirect.com
    Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum
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  70. Oct 2020
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Androgen Receptor signaling promotes the neural progenitor cell pool in the developing cortex
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  72. Sep 2020
  73. www.sciencedirect.com www.sciencedirect.com
    A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV
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  74. www.sciencedirect.com www.sciencedirect.com
    Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma
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    Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway
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  76. Jan 2020
  77. elifesciences.org elifesciences.org
    Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration
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      DOI: 10.7554/eLife.45853

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    Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
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    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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    sciencedirect.com/science/article/pii/S0960982219309327
  81. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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      DOI: 10.1016/j.cell.2019.09.008

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    sciencedirect.com/science/article/pii/S0092867419310141
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      DOI: 10.1016/j.celrep.2019.01.106

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      DOI: 10.1016/j.celrep.2019.01.105

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    sciencedirect.com/science/article/pii/S2211124719301421
  84. Nov 2018
  85. www.sciencedirect.com www.sciencedirect.com
    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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  86. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
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  87. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity
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    sciencedirect.com/science/article/pii/S0092867417310644
  88. Nov 2017
  89. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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    sciencedirect.com/science/article/pii/S1097276517304914
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    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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    sciencedirect.com/science/article/pii/S0960982217307236
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing
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