60 Matching Annotations
  1. Last 7 days
  2. media.springernature.com media.springernature.com
    41467_2026_75542_MOESM1_ESM.pdf
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    Brain assembloids reveal efficacy and off target effects in high grade glioma brain cancer
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    sciencedirect.com/science/article/pii/S2589004226026258
  4. Jul 2026
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    NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy model
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    sciencedirect.com/science/article/pii/S258900422602239X
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    Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis
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    sciencedirect.com/science/article/pii/S1934590926002286
  7. Jun 2026
  8. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    A Wireless 3D Magneto-Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.75958
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin-like growth factor 1 receptor regulates breast cancer cell adhesion through beta-1 integrin
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    pmc.ncbi.nlm.nih.gov/articles/PMC13229645/
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    Targeting the macrophage mechanosensing regulator CKAP4 accelerates the inflammatory-to-proliferative transition in wound healing
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    sciencedirect.com/science/article/pii/S2211124726004730
  11. Apr 2026
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    Atf3 Integrates Lipid and Cytoskeletal Remodeling to Drive Macrophage Fusion
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    biorxiv.org/content/10.64898/2026.04.01.715652v1
  13. Mar 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Divergent proteome tolerance against gain and loss of chromosome arms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12991381/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MRCKα Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12984664/
  16. Feb 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12876907/
  18. Nov 2025
  19. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models
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    Insulin-Like Growth Factor 1 Receptor Regulates Breast Cancer Cell Adhesion through Beta-1 Integrin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458451/
  21. Aug 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Scavenger Receptor CD36 in Tumor-Associated Macrophages Promotes Cancer Progression by Dampening Type I Interferon Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11788022/
  23. Jun 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
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  25. May 2025
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    Direct Arp2/3-vinculin binding is required for pseudopod extension, but only on compliant substrates and in 3D
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  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A
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  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux
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    onlinelibrary.wiley.com/doi/10.1111/eci.70051
  29. Apr 2025
  30. 52.53.155.43 52.53.155.43
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  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits
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  33. Mar 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Cofilactin rod formation mediates inflammation-induced neurite degeneration
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  35. Oct 2023
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    A Haspin-ARHGAP11A axis regulates epithelial morphogenesis through Rho-ROCK dependent modulation of LIMK1-Cofilin
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    sciencedirect.com/science/article/pii/S2589004223020886
  37. Sep 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  39. Aug 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZXDC Enhances Cervical Cancer Metastasis Through IGF2BP3-Mediated Activation of RhoA/ROCK Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10433122/
  41. www.nature.com www.nature.com
    Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
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    nature.com/articles/s42003-023-05223-0
  42. Mar 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977963/
  44. Feb 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Cofilin promotes tau pathology in Alzheimer’s disease
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  46. www.embopress.org www.embopress.org
    The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential
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    embopress.org/doi/10.15252/embr.202255069
  47. Dec 2022
  48. link.springer.com link.springer.com
    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
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    link.springer.com/article/10.1186/s10020-022-00581-7
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    Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios
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    sciencedirect.com/science/article/pii/S221112472201600X
  50. Nov 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation
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  52. www.researchsquare.com www.researchsquare.com
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  53. Sep 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice
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  55. Aug 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124722010798
  57. journals.plos.org journals.plos.org
    Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
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    A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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    sciencedirect.com/science/article/pii/S1550413122003084
  59. May 2022
  60. link.springer.com link.springer.com
    The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
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    link.springer.com/article/10.1007/s40618-022-01807-5
  61. Aug 2021
  62. www.sciencedirect.com www.sciencedirect.com
    The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies
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    sciencedirect.com/science/article/pii/S2211124721010391
  63. www.sciencedirect.com www.sciencedirect.com
    NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
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    sciencedirect.com/science/article/pii/S2211124721009451
  64. www.sciencedirect.com www.sciencedirect.com
    Sex-specific regulation of spine density and synaptic proteins by G-protein-coupled estrogen receptor (GPER)1 in developing hippocampus
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    sciencedirect.com/science/article/pii/S0306452221003894
  65. Jul 2021
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15448
  67. Jun 2021
  68. link.springer.com link.springer.com
    Vinculin-mediated axon growth requires interaction with actin but not talin in mouse neocortical neurons
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    link.springer.com/article/10.1007/s00018-021-03879-7
  69. May 2021
  70. www.sciencedirect.com www.sciencedirect.com
    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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  71. www.sciencedirect.com www.sciencedirect.com
    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
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  72. www.sciencedirect.com www.sciencedirect.com
    Dissecting ELANE neutropenia pathogenicity by human HSC gene editing
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  73. Apr 2021
  74. link.springer.com link.springer.com
    Semaphorin3F Drives Dendritic Spine Pruning Through Rho-GTPase Signaling
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    link.springer.com/article/10.1007/s12035-021-02373-2
  75. Mar 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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    ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
  77. www.sciencedirect.com www.sciencedirect.com
    Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK
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    sciencedirect.com/science/article/pii/S2211124721001145
  78. Jan 2021
  79. www.sciencedirect.com www.sciencedirect.com
    Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin
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    sciencedirect.com/science/article/pii/S0960982220318261
  80. Sep 2020
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    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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  82. www.sciencedirect.com www.sciencedirect.com
    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
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  83. www.jneurosci.org www.jneurosci.org
    Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination
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    jneurosci.org/content/40/15/2993
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact
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  85. Jan 2020
  86. www.sciencedirect.com www.sciencedirect.com
    RhoA Controls Axon Extension Independent of Specification in the Developing Brain
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  87. www.sciencedirect.com www.sciencedirect.com
    USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification
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  88. www.sciencedirect.com www.sciencedirect.com
    Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization
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  89. Nov 2018
  90. www.jneurosci.org www.jneurosci.org
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  92. Nov 2017
  93. cancerres.aacrjournals.org cancerres.aacrjournals.org
    LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
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    cancerres.aacrjournals.org/content/76/12/3541.full