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Hexokinase-2 moonlights as a suppressor of STING-mediated innate immunity

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1. scibot 24 Oct 2026
  
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  DOI: 10.1016/j.celrep.2026.118187
  
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sciencedirect.com/science/article/pii/S2211124726012660
Sep 2026
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The long non-coding RNA-encoded microprotein MKKS3 drives colorectal cancer chemoresistance

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  DOI: 10.1038/s12276-026-01817-w
  
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  DOI: 10.1038/s12276-026-01817-w
  
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nature.com/articles/s12276-026-01817-w
Aug 2026
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A STING inhibitor suppresses ferroptosis through radical-trapping antioxidant activity

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1. scibot 29 Aug 2026
  
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  DOI: 10.1016/j.chembiol.2026.08.004
  
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sciencedirect.com/science/article/pii/S2451945626002916
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SADS-CoV nucleocapsid protein antagonizes DAD1-mediated STING activation to prevent cytosolic DNA sensing

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1. scibot 29 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117917
  
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MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA

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1. scibot 13 Aug 2026
  
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  DOI: 10.1038/s41418-026-01834-2
  
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nature.com/articles/s41418-026-01834-2
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C3aR inhibition alleviates cerebral ischemia-reperfusion injury via STING-mediated ferroptosis through SLC7A11/GPX4

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1. scibot 03 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.116982
  
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sciencedirect.com/science/article/pii/S2589004226023606
Jun 2026
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PKCα-mediated nuclear translocation of cGAS stabilizes β-catenin and drives metastasis

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.05.023
  
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sciencedirect.com/science/article/pii/S1097276526003473
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Cytoplasmic relocation of nuclear Ku70 by Bruceine A augments cGAS–STING pathway-mediated anti-tumor immunity

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.apsb.2026.06.010
  
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sciencedirect.com/science/article/pii/S2211383526003400
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STING-OPTN signaling confers cytoprotection through TBK1-dependent mitophagy

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1. scibot 11 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117515
  
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sciencedirect.com/science/article/pii/S2211124726005930
Apr 2026
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FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.020
  
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1-s2.0-S2589004226010862-main-html.html

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1. scibot 11 Apr 2026
  
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54.241.53.176/be028d43344bab6907bc9e771fd88e2dec1a0cd7/1-s2.0-S2589004226010862-main-html.html
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advs74967-sup-0001-suppmat.docx-html.html

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1. scibot 11 Apr 2026
  
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  DOI: 10.1002/advs.202522764
  
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54.241.53.176/8f7474ccb0db38ef3abc02e1f9942a511c5917ed/advs74967-sup-0001-suppmat.docx-html.html
Feb 2026
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Regulation of AP1 adaptor assembly by the bi-handed chaperone MEA1

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1. scibot 24 Feb 2026
  
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  DOI: 10.1038/s41467-026-68662-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12923701/
Jan 2026
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Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression

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1. scibot 30 Jan 2026
  
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  DOI: 10.7150/ijbs.123790
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12836506/
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Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.013
  
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sciencedirect.com/science/article/pii/S1535610825005471
Dec 2025
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Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.002
  
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sciencedirect.com:5037/science/article/pii/S1550413125004863
Nov 2025
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Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.007
  
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sciencedirect.com/science/article/pii/S1074761325004613
Oct 2025
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Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116480
  
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sciencedirect.com/science/article/pii/S2211124725012513
Jun 2025
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A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence

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1. scibot 25 Jun 2025
  
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  DOI: 10.12688/f1000research.155929.2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12175898/
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ILC3s sense gut microbiota through STING to initiate immune tolerance

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.016
  
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sciencedirect.com/science/article/pii/S1074761325002377
May 2025
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Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition

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1. scibot 21 May 2025
  
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  DOI: 10.1186/s12974-025-03451-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12044788/
Apr 2025
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1-s2.0-S2589004225006522-main-html.html

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112391
  
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52.53.155.43/65da5ba6fe747fbc09139b682088b351a925dfd8/1-s2.0-S2589004225006522-main-html.html
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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.03.008
  
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
Mar 2025
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Diffuse Traumatic Brain Injury Induced Stimulator of Interferons (STING) Signaling in Microglia Drives Cortical Neuroinflammation, Neuronal Dysfunction, and Impaired Cognition

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1. scibot 13 Mar 2025
  
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  DOI: 10.21203/rs.3.rs-5960640/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875282/
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Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia

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  DOI: 10.1002/advs.202414260
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12021055/
Feb 2025
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Exercise-induced adipokine Nrg4 alleviates MASLD by disrupting hepatic cGAS-STING signaling

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  DOI: 10.1016/j.celrep.2025.115251
  
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sciencedirect.com/science/article/pii/S2211124725000221
Jan 2025
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Mechanical Force-Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis

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  DOI: 10.1002/advs.202401127
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202401127
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AIM2 promotes excitatory glutamate receptor expression by inhibiting STING and contributes to bone cancer pain in male mice

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  DOI: 10.1038/s41598-024-83027-w
  
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nature.com/articles/s41598-024-83027-w
Dec 2024
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MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling

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  DOI: 10.1016/j.molcel.2024.11.026
  
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The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.017
  
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sciencedirect.com/science/article/pii/S1074761324005326
Sep 2024
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Click-chemistry-based protocol for detecting 4-octyl-itaconate-alkylated proteins in primary mouse macrophages

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.xpro.2024.103314
  
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sciencedirect.com/science/article/pii/S2666166724004799
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
Jul 2024
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Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110144
  
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RGD Targeted Magnetic Ferrite Nanoparticles Enhance Antitumor Immunotherapeutic Efficacy by Activating STING Signaling Pathway

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1-s2.0-S2589004224002839-main-html.html

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Mar 2024
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Ebola virus sequesters IRF3 in viral inclusion bodies to evade host antiviral immunity

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Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses

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RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion

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Nov 2023
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Impaired cortical neuronal homeostasis and cognition after diffuse traumatic brain injury are dependent on microglia and type I interferon responses

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Itaconate inhibits SYK through alkylation and suppresses inflammation against hvKP induced intestinal dysbiosis

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Regulation of STING activity in DNA sensing by ISG15 modification

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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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4-Octyl itaconate restricts STING activation by blocking its palmitoylation

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STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages

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Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy

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C9ORF72 suppresses JAK-STAT mediated inflammation

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The mechanism of STING autoinhibition and activation

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis

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Mar 2023
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STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion

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Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING

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ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING

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4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING

1
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Stimulator of interferon genes (STING) expression in the enteric nervous system and contributions of glial STING in disease

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Jan 2023
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Protocol using lentivirus to establish THP-1 suspension cell lines for immunostaining and confocal microscopy

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Dec 2022
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Mitochondrial cristae architecture protects against mtDNA release and inflammation

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cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease

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Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy

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Jul 2022
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Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation

1
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Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C

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FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

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Apr 2021
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Mutant p53 suppresses innate immune signaling to promote tumorigenesis

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Feb 2021
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Reactive oxygen species oxidize STING and suppress interferon production

1
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Jan 2021
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A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA

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Sep 2020
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SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

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1. scibot 09 Sep 2020
  
  in Public
  
  RRID:AB_10665370
  
  DOI: 10.1016/j.celrep.2020.02.112
  
  Resource: (Proteintech Cat# 19851-1-AP, RRID:AB_10665370)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10665370
  
  What is this?
  
  RRID:AB_10665370 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112472030293X

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