33 Matching Annotations
  1. May 2024
  2. www.cell.com www.cell.com
    Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
    2
    1. scibot 03 May 2024
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2024.114165

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    2. scibot 03 May 2024
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2024.114165

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    cell.com/cell-reports/fulltext/S2211-1247(24)00493-5
  3. Nov 2023
  4. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
    1
    1. scibot 12 Nov 2023
      RRID:AB_10672401

      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  5. Jul 2023
  6. www.sciencedirect.com www.sciencedirect.com
    A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling
    1
    1. scibot 21 Jul 2023
      RRID:AB_10672401

      DOI: 10.1016/j.molcel.2023.06.024

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    sciencedirect.com/science/article/pii/S1097276523004719
  7. Jun 2023
  8. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
    1. scibot 28 Jun 2023
      RRID:AB_10672401

      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  9. www.sciencedirect.com www.sciencedirect.com
    A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth
    1
    1. scibot 27 Jun 2023
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2023.112688

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    sciencedirect.com/science/article/pii/S221112472300699X
  10. www.sciencedirect.com www.sciencedirect.com
    METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells
    1
    1. scibot 22 Jun 2023
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2023.112650

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    sciencedirect.com/science/article/pii/S2211124723006617
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease
    1
    1. scibot 15 Jun 2023
      RRID:AB_10672401

      DOI: 10.1111/jnc.15882

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15882
  12. www.sciencedirect.com www.sciencedirect.com
    Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells
    1
    1. scibot 03 Jun 2023
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2023.112596

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    sciencedirect.com/science/article/pii/S2211124723006071
  13. Oct 2022
  14. www.cell.com www.cell.com
    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
    1
    1. scibot 28 Oct 2022
      RRID:AB_10672401

      DOI: 10.1016/j.ccell.2022.10.004

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    cell.com/cancer-cell/fulltext/S1535-6108(22)00495-0
  15. www.sciencedirect.com www.sciencedirect.com
    METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma
    1
    1. scibot 26 Oct 2022
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2022.111530

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    sciencedirect.com/science/article/pii/S2211124722013869
  16. Aug 2022
  17. www.sciencedirect.com www.sciencedirect.com
    m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs
    1
    1. scibot 23 Aug 2022
      RRID:AB_10672401

      DOI: 10.1016/j.isci.2022.104908

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    sciencedirect.com/science/article/pii/S2589004222011804
  18. www.sciencedirect.com www.sciencedirect.com
    METTL14-dependent m6A modification controls iNKT cell development and function
    1
    1. scibot 06 Aug 2022
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2022.111156

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    sciencedirect.com/science/article/pii/S2211124722009652
  19. www.sciencedirect.com www.sciencedirect.com
    N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis
    1
    1. scibot 04 Aug 2022
      RRID:AB_10672401

      DOI: 10.1016/j.devcel.2022.07.006

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    sciencedirect.com/science/article/pii/S1534580722004956
  20. Jul 2022
  21. www.sciencedirect.com www.sciencedirect.com
    METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma
    1
    1. scibot 08 Jul 2022
      AB_10672401

      DOI: 10.1016/j.ebiom.2022.104142

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    sciencedirect.com/science/article/pii/S2352396422003231
  22. Mar 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
    1
    1. scibot 02 Mar 2022
      AB_10672401

      DOI: 10.1016/j.molcel.2022.02.006

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    sciencedirect.com/science/article/pii/S1097276522001113
  24. Oct 2021
  25. academic.oup.com academic.oup.com
    METTL3-mediated RNA m6A hypermethylation promotes tumorigenesis and GH secretion of pituitary somatotroph adenomas
    1
    1. scibot 20 Oct 2021
      RRID:AB_10672401

      DOI: 10.1210/clinem/dgab652

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab652/6365751
  26. May 2021
  27. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
    1
    1. scibot 28 May 2021
      RRID:AB_10672401

      DOI: 10.1016/j.ccell.2021.04.017

      Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S1535610821002257
  28. www.sciencedirect.com www.sciencedirect.com
    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
    1
    1. scibot 06 May 2021
      RRID:AB_10672401

      DOI: 10.1016/j.immuni.2020.05.003

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    sciencedirect.com/science/article/pii/S1074761320301849
  29. www.sciencedirect.com www.sciencedirect.com
    N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation
    1
    1. scibot 05 May 2021
      RRID:AB_10672401

      DOI: 10.1016/j.devcel.2020.10.023

      Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S1534580720308431
  30. Apr 2021
  31. www.sciencedirect.com www.sciencedirect.com
    YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis
    1
    1. scibot 22 Apr 2021
      RRID:AB_10672401

      DOI: 10.1016/j.ccell.2020.10.004

      Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S1535610820304980
  32. www.sciencedirect.com www.sciencedirect.com
    A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease
    1
    1. scibot 14 Apr 2021
      RRID:AB_10672401

      DOI: 10.1016/j.cmet.2021.03.024

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    sciencedirect.com/science/article/pii/S1550413121001315
  33. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
    1
    1. scibot 02 Apr 2021
      RRID:AB_10672401

      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  34. Mar 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine
    1
    1. scibot 03 Mar 2021
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2021.108798

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    sciencedirect.com/science/article/pii/S2211124721001121
  36. Jan 2020
  37. www.sciencedirect.com www.sciencedirect.com
    m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination
    1
    1. scibot 13 Jan 2020
      RRID:AB_10672401

      DOI: 10.1016/j.neuron.2019.12.013

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      Curator: @ethanbadger

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      RRID:AB_10672401 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319310554
  38. www.sciencedirect.com www.sciencedirect.com
    Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning
    1
    1. scibot 13 Jan 2020
      RRID:AB_10672401

      DOI: 10.1016/j.neuron.2018.06.007

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      RRID:AB_10672401 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627318304756
  39. www.sciencedirect.com www.sciencedirect.com
    Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection
    1
    1. scibot 13 Jan 2020
      RRID:AB_10672401

      DOI: 10.1016/j.molcel.2019.11.007

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      Curator: @ethanbadger

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      RRID:AB_10672401 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519308366
  40. www.sciencedirect.com www.sciencedirect.com
    Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site
    1
    1. scibot 13 Jan 2020
      RRID:AB_10672401

      DOI: 10.1016/j.celrep.2019.02.100

      Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)

      Curator: @ethanbadger

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      RRID:AB_10672401 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719302864
  41. www.sciencedirect.com www.sciencedirect.com
    Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex
    1
    1. scibot 12 Jan 2020
      RRID:AB_10672401

      DOI: 10.1016/j.molcel.2019.02.034

      Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)

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      RRID:AB_10672401 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519301455
  42. Nov 2018
  43. www.sciencedirect.com www.sciencedirect.com
    METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
    1
    1. scibot 05 Nov 2018
      RRID:AB_10672401

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      (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S193459091730468X
  44. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
    1
    1. scibot 05 Nov 2018
      RRID:AB_10672401

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      (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S1097276518300480
  45. www.sciencedirect.com www.sciencedirect.com
    Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
    1
    1. scibot 05 Nov 2018
      RRID:AB_10672401

      Curator: @Jmenke

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      (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S1097276518301345
  46. www.sciencedirect.com www.sciencedirect.com
    m6A Facilitates eIF4F-Independent mRNA Translation
    1
    1. scibot 05 Nov 2018
      RRID:AB_10672401

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      (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)

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    sciencedirect.com/science/article/pii/S1097276517307517