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43 Matching Annotations

Jun 2026
aacrjournals.org aacrjournals.org

ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation

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1. scibot 30 Jun 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-3975
  
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aacrjournals.org/cancerres/article/86/3/622/771927/ZC3H13-Loss-Drives-Cancer-Metastatic-Progression
Oct 2025
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Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116311
  
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sciencedirect.com/science/article/pii/S2211124725010824
Aug 2025
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Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation

1
1. scibot 07 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.014
  
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sciencedirect.com/science/article/pii/S0092867425008037
Jun 2025
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SSB cooperates with METTL16-mediated m6A RNA methylation to promote chemoresistance in colorectal cancer cells

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115926
  
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sciencedirect.com/science/article/pii/S2211124725006977
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RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115802
  
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sciencedirect.com/science/article/pii/S221112472500573X
May 2025
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IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.stem.2025.05.001
  
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sciencedirect.com/science/article/pii/S193459092500181X
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m6A RNA methylation-mediated control of global APC expression is required for local translation of β-actin and axon development

1
1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115727
  
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sciencedirect.com/science/article/pii/S221112472500498X
Mar 2025
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m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.stem.2025.02.011
  
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sciencedirect.com/science/article/pii/S1934590925000797
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Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.02.016
  
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sciencedirect.com/science/article/pii/S1097276525001479
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

1
1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12160003/
May 2024
www.cell.com www.cell.com

Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation

2
1. scibot 03 May 2024
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2024.114165
  
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2. scibot 03 May 2024
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2024.114165
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00493-5
Nov 2023
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mTORC1 promotes cell growth via m6A-dependent mRNA degradation

1
1. scibot 12 Nov 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.molcel.2021.03.010
  
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sciencedirect.com/science/article/pii/S1097276521001787
Jul 2023
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A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling

1
1. scibot 21 Jul 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.molcel.2023.06.024
  
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sciencedirect.com/science/article/pii/S1097276523004719
Jun 2023
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QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

1
1. scibot 28 Jun 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.cell.2023.05.047
  
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sciencedirect.com/science/article/pii/S0092867423005986
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A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth

1
1. scibot 27 Jun 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2023.112688
  
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sciencedirect.com/science/article/pii/S221112472300699X
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METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells

1
1. scibot 22 Jun 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2023.112650
  
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sciencedirect.com/science/article/pii/S2211124723006617
onlinelibrary.wiley.com onlinelibrary.wiley.com

METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease

1
1. scibot 15 Jun 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1111/jnc.15882
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15882
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Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells

1
1. scibot 03 Jun 2023
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2023.112596
  
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sciencedirect.com/science/article/pii/S2211124723006071
Oct 2022
www.cell.com www.cell.com

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

1
1. scibot 28 Oct 2022
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.ccell.2022.10.004
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00495-0
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METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma

1
1. scibot 26 Oct 2022
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2022.111530
  
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sciencedirect.com/science/article/pii/S2211124722013869
Aug 2022
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m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs

1
1. scibot 23 Aug 2022
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.isci.2022.104908
  
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sciencedirect.com/science/article/pii/S2589004222011804
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METTL14-dependent m6A modification controls iNKT cell development and function

1
1. scibot 06 Aug 2022
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2022.111156
  
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sciencedirect.com/science/article/pii/S2211124722009652
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis

1
1. scibot 04 Aug 2022
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.devcel.2022.07.006
  
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sciencedirect.com/science/article/pii/S1534580722004956
Jul 2022
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METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma

1
1. scibot 08 Jul 2022
  
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  AB_10672401
  
  DOI: 10.1016/j.ebiom.2022.104142
  
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sciencedirect.com/science/article/pii/S2352396422003231
Mar 2022
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Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis

1
1. scibot 02 Mar 2022
  
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  AB_10672401
  
  DOI: 10.1016/j.molcel.2022.02.006
  
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sciencedirect.com/science/article/pii/S1097276522001113
Oct 2021
academic.oup.com academic.oup.com

METTL3-mediated RNA m6A hypermethylation promotes tumorigenesis and GH secretion of pituitary somatotroph adenomas

1
1. scibot 20 Oct 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1210/clinem/dgab652
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab652/6365751
May 2021
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N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

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1. scibot 28 May 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.ccell.2021.04.017
  
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sciencedirect.com/science/article/pii/S1535610821002257
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m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.05.003
  
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sciencedirect.com/science/article/pii/S1074761320301849
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation

1
1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.10.023
  
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sciencedirect.com/science/article/pii/S1534580720308431
Apr 2021
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YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis

1
1. scibot 22 Apr 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.ccell.2020.10.004
  
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sciencedirect.com/science/article/pii/S1535610820304980
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A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease

1
1. scibot 14 Apr 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.cmet.2021.03.024
  
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sciencedirect.com/science/article/pii/S1550413121001315
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mTORC1 promotes cell growth via m6A-dependent mRNA degradation

1
1. scibot 02 Apr 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.molcel.2021.03.010
  
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sciencedirect.com/science/article/pii/S1097276521001787
Mar 2021
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine

1
1. scibot 03 Mar 2021
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2021.108798
  
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  RRID:AB_10672401 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721001121
Jan 2020
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m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.neuron.2019.12.013
  
  Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)
  
  Curator: @ethanbadger
  
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  RRID:AB_10672401 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627319310554
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Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning

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1. scibot 13 Jan 2020
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.neuron.2018.06.007
  
  Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)
  
  Curator: @Naa003
  
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  RRID:AB_10672401 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627318304756
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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

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1. scibot 13 Jan 2020
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.molcel.2019.11.007
  
  Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)
  
  Curator: @ethanbadger
  
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  RRID:AB_10672401 RRIDCUR:Validated
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Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site

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1. scibot 13 Jan 2020
  
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  RRID:AB_10672401
  
  DOI: 10.1016/j.celrep.2019.02.100
  
  Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)
  
  Curator: @ethanbadger
  
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  RRID:AB_10672401 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719302864
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Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_10672401
  
  DOI: 10.1016/j.molcel.2019.02.034
  
  Resource: (Sigma-Aldrich Cat# HPA038002, RRID:AB_10672401)
  
  Curator: @ethanbadger
  
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  RRID:AB_10672401 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519301455
Nov 2018
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METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10672401
  
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  (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)
  
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sciencedirect.com/science/article/pii/S193459091730468X
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N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10672401
  
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  (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)
  
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Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_10672401
  
  Curator: @Jmenke
  
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  (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)
  
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sciencedirect.com/science/article/pii/S1097276518301345
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m6A Facilitates eIF4F-Independent mRNA Translation

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10672401
  
  Resource used:
  
  (Atlas Antibodies Cat# HPA038002, RRID:AB_10672401)
  
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sciencedirect.com/science/article/pii/S1097276517307517