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A stroma-sensing TGF-β blockade reprograms CAF-myeloid niches to induce durable tumor immunity

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.ccell.2026.10.007
  
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sciencedirect.com/science/article/pii/S1535610826004733
Sep 2026
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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

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  DOI: 10.1016/j.molcel.2026.08.007
  
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sciencedirect.com/science/article/pii/S109727652600554X
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Aging microenvironment induces CD8+ T cell exhaustion by suppressing hepatic β-hydroxybutyrylate synthesis

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1. scibot 04 Sep 2026
  
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  DOI: 10.1016/j.cmet.2026.08.009
  
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sciencedirect.com/science/article/pii/S1550413126003347
Aug 2026
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Subclinical cholestasis is a hallmark of gut dysbiosis causing resistance to cancer immunotherapy

1
1. scibot 01 Aug 2026
  
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  DOI: 10.1016/j.ccell.2026.06.022
  
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sciencedirect.com/science/article/pii/S1535610826003090
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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1. scibot 18 Jun 2026
  
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  DOI: 10.1126/sciadv.aee0517
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13262630/
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Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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  DOI: 10.1126/sciadv.aee0517
  
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science.org/doi/10.1126/sciadv.aee0517
May 2026
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mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
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Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity

1
1. scibot 01 May 2026
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.ccell.2026.03.023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13215210/
Apr 2026
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STAT5 activation enhances adoptive therapy combined with peptide vaccination by preventing PD-1 inhibition

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1. scibot 02 Apr 2026
  
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  RRID:AB_10680238
  
  DOI: 10.1158/1535-7163.MCT-24-0505
  
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aacrjournals.org/mct/article/24/3/419/752080/STAT5-Activation-Enhances-Adoptive-Therapy
Dec 2025
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An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery

1
1. scibot 17 Dec 2025
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2025.102515
  
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sciencedirect.com:5037/science/article/pii/S2666379125005889
Oct 2025
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

1
1. scibot 08 Oct 2025
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
Aug 2025
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116177
  
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sciencedirect.com/science/article/pii/S2211124725009489
Jul 2025
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Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization

1
1. scibot 15 Jul 2025
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.isci.2025.112992
  
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sciencedirect.com/science/article/pii/S2589004225012532
May 2025
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Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein

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1. scibot 20 May 2025
  
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  RRID:AB_10680238
  
  DOI: 10.1136/jitc-2024-010831
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12067867/
Dec 2024
www.cell.com www.cell.com

Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

1
1. scibot 29 Dec 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
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Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

1
1. scibot 29 Dec 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.ccell.2024.12.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
52.53.155.43 52.53.155.43

can-24-1611-html.html

3
1. scibot 19 Dec 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1158/0008-5472.can-24-1611
  
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2. scibot 19 Dec 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1158/0008-5472.can-24-1611
  
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  RRID:AB_10680238
  
  DOI: 10.1158/0008-5472.can-24-1611
  
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52.53.155.43/75f09a51d2e08f557660a3e31ff8f3f3198b5c01/can-24-1611-html.html
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115056
  
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sciencedirect.com/science/article/pii/S2211124724014074
Jun 2024
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A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice

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  DOI: 10.1038/s41590-024-01834-9
  
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nature.com/articles/s41590-024-01834-9
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Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.001
  
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sciencedirect.com/science/article/pii/S1550413124001773
May 2024
www.biorxiv.org www.biorxiv.org

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

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1. scibot 09 May 2024
  
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  BioLegend, catalogue #135214
  
  DOI: 10.1101/2024.01.23.576951
  
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biorxiv.org/content/10.1101/2024.01.23.576951v1
Feb 2024
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

1
1. scibot 02 Feb 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.celrep.2024.113712
  
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sciencedirect.com/science/article/pii/S2211124724000408
Jan 2024
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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

1
1. scibot 19 Jan 2024
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2023.101377
  
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sciencedirect.com/science/article/pii/S2666379123006067
Sep 2023
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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

1
1. scibot 29 Sep 2023
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.jaci.2023.07.015
  
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sciencedirect.com/science/article/pii/S0091674923009818
Aug 2023
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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

1
1. scibot 16 Aug 2023
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2023.101154
  
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sciencedirect.com/science/article/pii/S2666379123003075
Mar 2023
europepmc.org europepmc.org

mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy

1
1. scibot 22 Mar 2023
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2023.100978
  
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europepmc.org/article/med/36933554
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

1
1. scibot 16 Mar 2023
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.ccell.2023.02.005
  
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sciencedirect.com/science/article/pii/S1535610823000338
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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

1
1. scibot 10 Mar 2023
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.cmet.2023.02.013
  
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sciencedirect.com/science/article/pii/S1550413123000499
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer

1
1. scibot 04 Feb 2023
  
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  DOI: 10.1158/2326-6066.CIR-22-0088
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9357105/
Jul 2022
52.53.155.43 52.53.155.43

cir-22-0088-html.html

1
1. scibot 29 Jul 2022
  
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  RRID:AB_10680238
  
  DOI: 10.1158/2326-6066.CIR-22-0088
  
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52.53.155.43/a65b09b78e7767f723c9ad153c89aec9ed13d4e6/cir-22-0088-html.html
May 2022
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

1
1. scibot 12 May 2022
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.cell.2022.04.019
  
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sciencedirect.com/science/article/pii/S0092867422004664
Dec 2021
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Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity

1
1. scibot 08 Dec 2021
  
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  RRID:AB_10680238
  
  DOI: 10.1016/j.celrep.2021.110083
  
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sciencedirect.com/science/article/pii/S2211124721015746
Jul 2021
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The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis

1
1. scibot 28 Jul 2021
  
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  PD-1 FITC (clone 29F.1A12)
  
  DOI: 10.1016/j.immuni.2019.05.022
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
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sciencedirect.com/science/article/pii/S1074761319302420
May 2021
aacrjournals.org aacrjournals.org

A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

1
1. scibot 10 May 2021
  
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  RRID:AB_10680238
  
  DOI: 10.1158/0008-5472.CAN-20-3510
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10680238
  
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  RRID:AB_10680238
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RRID:AB_10680238

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scibot

URL

aacrjournals.org/cancerres/article/81/9/2358/670580/A-MyD88-IL1R-Axis-Regulates-PD-1-Expression-on
www.sciencedirect.com www.sciencedirect.com

In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_10680238
  
  DOI: 10.1016/j.immuni.2021.01.001
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10680238
  
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  RRID:AB_10680238
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RRID:AB_10680238

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scibot

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sciencedirect.com/science/article/pii/S1074761321000017
Sep 2020
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An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_10680238
  
  DOI: 10.1016/j.xcrm.2020.100035
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10680238
  
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  RRID:AB_10680238 RRIDCUR:Validated
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RRID:AB_10680238

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2666379120300471
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10680238
  
  DOI: 10.1016/j.ccell.2019.10.006
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10680238
  
  What is this?
  
  RRID:AB_10680238 RRIDCUR:Validated
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RRID:AB_10680238

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819304805
www.sciencedirect.com www.sciencedirect.com

Helminth Infections Suppress the Efficacy of Vaccination against Seasonal Influenza

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10680238
  
  DOI: 10.1016/j.celrep.2019.10.051
  
  Resource: (BioLegend Cat# 135214, RRID:AB_10680238)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10680238
  
  What is this?
  
  RRID:AB_10680238 RRIDCUR:Validated
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RRID:AB_10680238

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S2211124719313658