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Lung neuroendocrine cancer induces immunosuppressive macrophages via serotonin to drive resistance to the T cell engager tarlatamab

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1. scibot 24 Oct 2026
  
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  DOI: 10.1016/j.ccell.2026.09.016
  
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sciencedirect.com/science/article/pii/S1535610826004356
Sep 2026
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IL-1α Expands SLC2A1highSPP1highIFNlow Myeloid Cells to Drive Immune Escape and Malignant Transformation of Pre-cancers

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1. scibot 09 Sep 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4416
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13543150/
Apr 2026
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Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117303
  
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sciencedirect.com/science/article/pii/S2211124726003815
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Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0488
  
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aacrjournals.org/cancerimmunolres/article/13/12/2054/768330/Functional-Genetic-Screens-Reveal-Key-Pathways
Mar 2026
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Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.021
  
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sciencedirect.com/science/article/pii/S1074761326000919
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In vivo CAR-Tfh cell reprogramming restores tolerance in a mouse model of autoimmune hepatitis

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.02.006
  
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sciencedirect.com/science/article/pii/S1934590926000767
Nov 2025
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Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102446
  
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sciencedirect.com/science/article/pii/S2666379125005191
Oct 2025
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Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116470
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
Jul 2025
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Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.07.004
  
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sciencedirect.com/science/article/pii/S1074761325003139
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
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Bispecific targeting of 4-1BB and CCR8 boosts antitumor immunity via Ti-Treg depletion and CD8+ activation

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112829
  
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sciencedirect.com/science/article/pii/S2589004225010909
Apr 2025
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Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115592
  
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sciencedirect.com/science/article/pii/S2211124725003638
Mar 2025
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Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

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1. scibot 24 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
Oct 2024
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A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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1. scibot 04 Oct 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-3257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
Sep 2024
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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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1. scibot 27 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101747
  
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sciencedirect.com/science/article/pii/S2666379124004774
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114686
  
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sciencedirect.com/science/article/pii/S2211124724010374
Jun 2024
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Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114377
  
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sciencedirect.com/science/article/pii/S2211124724007058
May 2024
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Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.024
  
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sciencedirect.com/science/article/pii/S1074761324002292
Apr 2024
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

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1. scibot 12 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101479
  
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sciencedirect.com/science/article/pii/S2666379124001253
Dec 2023
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Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108504
  
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sciencedirect.com/science/article/pii/S2589004223025816
Jun 2023
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Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112649
  
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sciencedirect.com/science/article/pii/S2211124723006605
May 2023
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Asymmetric cell division safeguards memory CD8 T cell development

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1. scibot 13 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112468
  
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sciencedirect.com/science/article/pii/S2211124723004795
Mar 2023
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MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity

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1. scibot 30 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112310
  
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sciencedirect.com/science/article/pii/S2211124723003212
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Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112303
  
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europepmc.org/article/med/36952341
Dec 2022
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Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection

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1. scibot 01 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111736
  
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sciencedirect.com/science/article/pii/S221112472201614X
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105233
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
Jun 2022
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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.05.003
  
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sciencedirect.com/science/article/pii/S1074761322002230
Jan 2022
www-sciencedirect-com.libproxy.snu.ac.kr www-sciencedirect-com.libproxy.snu.ac.kr

Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells

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1. scibot 27 Jan 2022
  
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  DOI: 10.1016/j.immuni.2021.12.015
  
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www-sciencedirect-com.libproxy.snu.ac.kr/science/article/pii/S1074761321005513
Dec 2021
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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110064
  
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sciencedirect.com/science/article/pii/S2211124721015503
Nov 2021
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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109916
  
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sciencedirect.com/science/article/pii/S2211124721013899
Sep 2021
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A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells

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1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.029
  
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sciencedirect.com/science/article/pii/S1074761321003630
Aug 2021
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Untitled document

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1. scibot 07 Aug 2021
  
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  DOI: 10.1016/j.celrep.2018.11.047
  
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sciencedirect.com/science/article/pii/S2211124718318102
Apr 2021
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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1. scibot 01 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.03.007
  
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  RRIDCUR:Validated RRID:AB_10689635
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sciencedirect.com/science/article/pii/S1074761321001199
Mar 2021
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Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

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1. scibot 08 Mar 2021
  
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  DOI: 10.1016/j.immuni.2020.11.005
  
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sciencedirect.com/science/article/pii/S1074761320304921
Feb 2021
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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.ccell.2020.11.005
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
Oct 2020
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In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

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1. scibot 01 Oct 2020
  
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  DOI: 10.1016/j.immuni.2020.09.002
  
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sciencedirect.com/science/article/pii/S1074761320303964
Sep 2020
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An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.04.030
  
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sciencedirect.com/science/article/pii/S0092867420304931
Jan 2020
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Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.012
  
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sciencedirect.com/science/article/pii/S2211124719313129
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PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage

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1. scibot 13 Jan 2020
  
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  RRID:AB_10689635
  
  DOI: 10.1016/j.celrep.2019.10.092
  
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sciencedirect.com/science/article/pii/S2211124719314147
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6033538/
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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1074761318300062
Nov 2017
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Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

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1. scibot 08 Nov 2017
  
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  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1931312817302056