159 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes
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    1. scibot 14 Nov 2024
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      DOI: 10.1038/s44319-024-00289-1

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    pmc.ncbi.nlm.nih.gov/articles/PMC11549480/
  3. www.sciencedirect.com www.sciencedirect.com
    USP7 deubiquitinates KRAS and promotes non-small cell lung cancer
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.celrep.2024.114917

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    sciencedirect.com/science/article/pii/S2211124724012683
  4. journals.lww.com journals.lww.com
    Reduced mesencephalic astrocyte-derived neurotrophic factor ... : Neural Regeneration Research
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    1. scibot 07 Nov 2024
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      DOI: 10.4103/NRR.NRR-D-23-01666

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    journals.lww.com/nrronline/fulltext/2025/09000/reduced_mesencephalic_astrocyte_derived.27.aspx
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination
    1
    1. scibot 07 Nov 2024
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      DOI: 10.1083/jcb.202310143

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    pmc.ncbi.nlm.nih.gov/articles/PMC11040499/
  6. Sep 2024
  7. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structure of Phospholipase Cε Defines N-terminal Domains and their Roles in Activity
    1
    1. scibot 29 Sep 2024
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      DOI: 10.1101/2024.09.11.612521

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    biorxiv.org/content/10.1101/2024.09.11.612521v1
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of barotaxis in marine zooplankton
    1
    1. scibot 25 Sep 2024
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      DOI: 10.7554/eLife.94306

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    ncbi.nlm.nih.gov/pmc/articles/PMC11412693/
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    Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.neuron.2024.08.009

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    sciencedirect.com/science/article/pii/S0896627324005816
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.014

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    sciencedirect.com/science/article/pii/S009286742400905X
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
    1
    1. scibot 28 Aug 2024
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    sciencedirect.com/science/article/pii/S1534580724004866
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    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
    1
    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009689
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
    1
    1. scibot 21 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1083/jcb.202305003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857907/
  16. Jul 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.celrep.2021.108753

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    ncbi.nlm.nih.gov/pmc/articles/PMC7945993/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila
    1
    1. scibot 20 Jul 2024
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      DOI: 10.7554/eLife.53103

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    ncbi.nlm.nih.gov/pmc/articles/PMC7274782/
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    Dimerization of hub protein DYNLL1 and bZIP transcription factor CREB3L1 enhances transcriptional activation of CREB3L1 target genes like arginine vasopressin
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.peptides.2024.171269

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    sciencedirect.com/science/article/pii/S0196978124001220
  20. www.cell.com www.cell.com
    Sequence variations and accessory proteins adapt TMC functions to distinct sensory modalities
    2
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.neuron.2024.06.013

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    2. scibot 11 Jul 2024
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      DOI: 10.1016/j.neuron.2024.06.013

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    cell.com/neuron/abstract/S0896-6273(24)00448-3
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    The hydrophobicity of the CARD8 N-terminus tunes inflammasome activation
    1
    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.chembiol.2024.06.004

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    sciencedirect.com/science/article/pii/S245194562400223X
  22. Jun 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
  24. May 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
    1
    1. scibot 17 May 2024
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      DOI: 10.1016/j.molcel.2024.04.014

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    sciencedirect.com/science/article/pii/S1097276524003290
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
    1
    1. scibot 01 May 2024
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      DOI: 10.1101/2024.04.19.590338

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
  27. Apr 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.devcel.2024.04.005

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    sciencedirect.com/science/article/pii/S1534580724002302
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Cofilin function in the somatosensory cortex alters social contact behavior in the BTBR mouse inbred line
    1
    1. scibot 13 Apr 2024
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      DOI: 10.1093/cercor/bhae136

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    ncbi.nlm.nih.gov/pmc/articles/PMC11008688/
  30. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors
    1
    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.chembiol.2024.03.004

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    sciencedirect.com/science/article/pii/S245194562400120X
  31. Mar 2024
  32. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
    1
    1. scibot 21 Mar 2024
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      DOI: 10.1101/2024.03.03.583221

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    biorxiv.org/content/10.1101/2024.03.03.583221v1
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
    2
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.035

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      DOI: 10.1016/j.molcel.2024.02.035

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    sciencedirect.com/science/article/pii/S109727652400176X
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pip5k1γ regulates axon formation by limiting Rap1 activity
    1
    1. scibot 07 Mar 2024
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      DOI: 10.26508/lsa.202302383

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912816/
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    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.006

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    sciencedirect.com/science/article/pii/S1097276524001254
  36. Feb 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001736
  38. 52.53.155.43 52.53.155.43
    Regulation of the intestinal Na+/H+ exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563
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    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajpcell.00540.2023

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      DOI: 10.1152/ajpcell.00540.2023

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    52.53.155.43/f69a85cf28386bd1400aa251e3a5d55dee473eb1/han-et-al-2024-regulation-of-the-intestinal-na-h-exchanger-nhe3-by-amp-activated-kinase-is-dependent-on-phosphorylation-html.html
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    C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line
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    sciencedirect.com/science/article/pii/S1097276524000509
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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      DOI: 10.1016/j.isci.2024.108858

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
  41. Dec 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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      DOI: 10.1016/j.chembiol.2023.11.010

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    sciencedirect.com/science/article/pii/S2451945623004257
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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      DOI: 10.1038/s41419-023-06312-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  44. Oct 2023
  45. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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      DOI: 10.15252/embr.202356815

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    embopress.org/doi/10.15252/embr.202356815
  46. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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  47. Sep 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
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      DOI: 10.1016/j.chom.2023.08.003

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    sciencedirect.com/science/article/pii/S1931312823003281
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
    1
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    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites
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    Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5
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    An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes
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    MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
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  96. May 2022
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  99. Apr 2022
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    Site-Specific Incorporation of Genetically Encoded Photo-Crosslinkers Locates the Heteromeric Interface of a GPCR Complex in Living Cells
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
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    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
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    Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel
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  161. insight.jci.org insight.jci.org
    The RNFT2/IL3Rα axis regulates IL3 signaling and innate immunity
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    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
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  163. genesdev.cshlp.org genesdev.cshlp.org
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
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  164. Jan 2020
  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains
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  166. insight.jci.org insight.jci.org
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    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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    C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms
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    Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
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  170. elifesciences.org elifesciences.org
    The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila
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    Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder
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    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    Lack of PDZD7 long isoform disrupts ankle‐link complex and causes hearing loss in mice
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  174. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration
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    LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
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  181. Nov 2018
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    GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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    BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
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    Mechanotransduction by PCDH15 Relies on a Novel cis-Dimeric Architecture
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    Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
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    SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein
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    Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
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    Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
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    Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
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  196. Nov 2017
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    ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
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    Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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      (Cell Signaling Technology Cat# 2367S, RRID:AB_10691311)

      SciCrunch record: RRID:AB_10691311

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_10691311 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416315914
  200. www.sciencedirect.com www.sciencedirect.com
    A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density
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    1. scibot 08 Nov 2017
      AB_10691311

      Curator: @jcabotaj

      Resource used:

      (Cell Signaling Technology Cat# 2367S, RRID:AB_10691311)

      SciCrunch record: RRID:AB_10691311

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_10691311 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627315011265