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Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C–mutant non-small cell lung cancer

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1. scibot 07 Jul 2026
  
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  RRID: AB_10691324
  
  DOI: 10.1038/s41388-026-03877-8
  
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nature.com/articles/s41388-026-03877-8
Apr 2026
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ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging

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1. scibot 30 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.04.010
  
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sciencedirect.com/science/article/pii/S0092867426003995
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer

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1. scibot 14 Jan 2026
  
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  RRID:AB_10691324
  
  DOI: 10.1158/2159-8290.CD-25-0605
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
Jun 2025
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

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1. scibot 11 Jun 2025
  
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  RRID:AB_10691324
  
  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

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1. scibot 20 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2220
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Oct 2024
aacrjournals.org aacrjournals.org

Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases

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1. scibot 02 Oct 2024
  
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  RRID:AB_10691324
  
  DOI: 10.1158/1535-7163.MCT-20-0590
  
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aacrjournals.org/mct/article/20/3/564/92877/Identification-of-Predictive-ERBB-Mutations-by
Jun 2023
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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.ccell.2023.05.016
  
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sciencedirect.com/science/article/pii/S1535610823001836
Jun 2022
www.jneurosci.org www.jneurosci.org

Disruption of endosomal sorting in Schwann cells leads to defective myelination and endosomal abnormalities observed in Charcot-Marie-Tooth disease

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1. scibot 23 Jun 2022
  
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  RRID:AB_10691324
  
  DOI: 10.1523/JNEUROSCI.2481-21.2022
  
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jneurosci.org/content/42/25/5085
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study

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1. scibot 30 Sep 2021
  
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  RRID:AB_10691324
  
  DOI: 10.21037/tlcr-21-216
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
Jul 2021
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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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1. scibot 29 Jul 2021
  
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  RRID:AB_10691324
  
  DOI: 10.1016/j.celrep.2021.109455
  
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sciencedirect.com/science/article/pii/S221112472100872X
May 2021
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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.06.021
  
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sciencedirect.com/science/article/pii/S1934590920302885
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

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1. scibot 11 Apr 2021
  
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  RRID:AB_10691324
  
  DOI: 10.1016/j.molcel.2021.01.033
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8384339/
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

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1. scibot 11 Sep 2020
  
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  RRID:AB_10691324
  
  DOI: 10.1016/j.ccell.2020.06.005
  
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  Curator: @Naa003
  
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  RRID:AB_10691324 RRIDCUR:Validated
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pubmed.ncbi.nlm.nih.gov/32679108/
Nov 2018
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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818301740