181 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells
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    1. scibot 10 Nov 2024
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      DOI: 10.7554/eLife.97854

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    pmc.ncbi.nlm.nih.gov/articles/PMC11542922/
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
    1
    1. scibot 05 Oct 2024
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      DOI: 10.1101/2024.09.09.612106

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    ncbi.nlm.nih.gov/pmc/articles/PMC11419079/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.cmet.2024.07.019

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    sciencedirect.com/science/article/pii/S1550413124002900
  7. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.cell.2020.02.019

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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    Sex-Dimorphic Effects of Glucose Transporter-2 Gene Knockdown on Hypothalamic Primary Astrocyte Phosphoinositide-3-kinase (PI3K)/Protein Kinase B (PKB/Akt)/Mammalian Target of Rapamycin (mTOR) Cascade Protein Expression and Phosphorylation
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.mce.2024.112341

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    sciencedirect.com/science/article/pii/S0303720724001977
  9. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
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    1. scibot 02 Aug 2024
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      DOI: 10.1186/s13578-021-00640-2

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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  10. Jul 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
    1
    1. scibot 30 Jul 2024
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      DOI: 10.1016/j.jare.2024.07.024

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    sciencedirect.com/science/article/pii/S2090123224003096
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    Canagliflozin Attenuates Post-Resuscitation Myocardial Dysfunction in Diabetic Rats by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway
    1
    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S2589004224016547
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    PIK3CA mutations enhance the adipogenesis of ADSCs in facial infiltrating lipomatosis through TRPV1
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.isci.2024.110467

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    sciencedirect.com/science/article/pii/S2589004224016924
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101645

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  15. Jun 2024
  16. www.sciencedirect.com www.sciencedirect.com
    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
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    1. scibot 21 Jun 2024
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  17. 52.53.155.43 52.53.155.43
    Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency
    2
    1. scibot 06 Jun 2024
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      DOI: 10.1101/2024.02.09.579580

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      DOI: 10.1101/2024.02.09.579580

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    52.53.155.43/be49547c4f9e1293474726024249294abe2db848/2024.02.09.579580v1.full-html.html
  18. May 2024
  19. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 30 May 2024
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      DOI: 10.1111/bph.16420

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
  20. academic.oup.com academic.oup.com
    Adiponectin inhibits the progression of obesity-associated papillary thyroid carcinoma through autophagy
    1
    1. scibot 22 May 2024
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      DOI: 10.1210/endocr/bqae030

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    academic.oup.com/endo/article-abstract/165/5/bqae030/7630457
  21. 52.53.155.43 52.53.155.43
    2024.02.09.579580v1.full-html.html
    2
    1. scibot 10 May 2024
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      DOI: 10.1038/nature05972

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      DOI: 10.1101/2024.02.09.579580

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  22. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
    1
    1. scibot 10 May 2024
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      DOI: 10.1016/j.xcrm.2024.101552

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    sciencedirect.com/science/article/pii/S2666379124002441
  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 May 2024
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      DOI: 10.1111/bph.16391

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16391
  24. www.cell.com www.cell.com
    Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma
    1
    1. scibot 03 May 2024
      RRID:AB_10691552

      DOI: 10.1016/j.xcrm.2024.101519

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00188-5
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
    1
    1. scibot 01 May 2024
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      DOI: 10.21203/rs.3.rs-4114038/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030525/
  26. Apr 2024
  27. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.021

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    sciencedirect.com/science/article/pii/S1074761324001420
  28. www.sciencedirect.com www.sciencedirect.com
    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
  29. www.sciencedirect.com www.sciencedirect.com
    Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.ebiom.2024.105099

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    sciencedirect.com/science/article/pii/S2352396424001348
  30. Mar 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome
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    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113935

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      DOI: 10.1016/j.celrep.2024.113935

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    sciencedirect.com/science/article/pii/S2211124724002638
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTBC1D22A inhibits the progression of colorectal cancer through autophagy regulated via miR-1825/ATG14 axis
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.isci.2024.109168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10910227/
  33. Feb 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Trichinella spiralis inhibits myoblast differentiation by targeting SQSTM1/p62 with a secreted E3 ubiquitin ligase
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    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.isci.2024.109102

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      DOI: 10.1016/j.isci.2024.109102

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    sciencedirect.com/science/article/pii/S2589004224003237
  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
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      DOI: 10.1111/bph.16283

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  36. content.iospress.com content.iospress.com
    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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    1. scibot 16 Feb 2024
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      DOI: 10.3233/JAD-221058

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221058
  37. www.sciencedirect.com www.sciencedirect.com
    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    sciencedirect.com/science/article/pii/S2211124724000421
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
    1
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    sciencedirect.com/science/article/pii/S1550413124000068
  39. Jan 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
    2
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      DOI: 10.1126/sciadv.adi2012

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      DOI: 10.1126/sciadv.adi2012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  41. www.sciencedirect.com www.sciencedirect.com
    Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation
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      DOI: 10.1016/j.molcel.2024.01.002

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    sciencedirect.com/science/article/pii/S1097276524000030
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    Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival
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      DOI: 10.1016/j.isci.2024.108795

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    sciencedirect.com/science/article/pii/S2589004224000166
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
    1
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      DOI: 10.1016/j.cmet.2023.12.016

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    sciencedirect.com/science/article/pii/S1550413123004679
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Akt activation ameliorates deficits in hippocampal-dependent memory and activity-dependent synaptic protein synthesis in an Alzheimer’s disease mouse model
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      DOI: 10.1016/j.jbc.2023.105619

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    pmc.ncbi.nlm.nih.gov/articles/PMC10839450/
  45. Dec 2023
  46. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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      DOI: 10.1016/j.isci.2023.108596

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    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
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    Astragaloside IV promotes cerebral angiogenesis and neurological recovery after focal ischemic stroke in mice via activating PI3K/Akt/mTOR signaling pathway
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    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways
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  144. Oct 2021
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    Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer
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  154. Jul 2021
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    Functional expression of electrogenic sodium bicarbonate cotransporter 1 (NBCe1) in mouse cortical astrocytes is dependent on S255‐257 and regulated by mTOR
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    Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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    Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming
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    Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate
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    Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    Exogenous H2S exerts biphasic effects on porcine mammary epithelial cells proliferation through PI3K/Akt‐mTOR signaling pathway
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    Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin
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    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
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    Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
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    Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
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    PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
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