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SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

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1. scibot 10 Jun 2026
  
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  RRID:AB_10691557
  
  DOI: 10.1158/0008-5472.CAN-25-3195
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13244386/
Nov 2025
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Inhibition of oligomeric BAX by an anti-apoptotic dimer

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.037
  
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sciencedirect.com/science/article/pii/S0092867425012425
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma

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1. scibot 08 Nov 2025
  
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  AB_10691557
  
  DOI: 10.1158/1078-0432.CCR-20-0018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8440125/
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dissecting the Neuroprotective Interaction Between the BH4 Domain of BCL-w and IP3 Receptor

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1. scibot 21 Oct 2025
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.chembiol.2024.06.016
  
  Resource: (Cell Signaling Technology Cat# 2724, RRID:AB_10691557)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11490406/
Jul 2025
www.biorxiv.org www.biorxiv.org

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance

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1. scibot 11 Jul 2025
  
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  DOI: 10.1101/2025.06.24.661170
  
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biorxiv.org/content/10.1101/2025.06.24.661170v1
Jun 2025
www.cell.com www.cell.com

BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways

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1. scibot 13 Jun 2025
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.celrep.2025.115779
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
Sep 2023
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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

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1. scibot 19 Sep 2023
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.celrep.2023.113084
  
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sciencedirect.com/science/article/pii/S2211124723010951
Feb 2023
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IFNγ signaling sensitizes melanoma cells to BH3 Mimetics

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1. scibot 04 Feb 2023
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.jid.2023.01.017
  
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sciencedirect.com/science/article/pii/S0022202X23000726
Aug 2021
www.nature.com www.nature.com

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

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1. scibot 16 Aug 2021
  
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  RRID:AB_10691557
  
  DOI: 10.1038/s41467-021-24821-2
  
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nature.com/articles/s41467-021-24821-2
Sep 2020
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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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1. scibot 04 Sep 2020
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.ccell.2019.12.006
  
  Resource: (Cell Signaling Technology Cat# 2724, RRID:AB_10691557)
  
  Curator: @ethanbadger
  
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  RRID:AB_10691557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819305768
Jan 2020
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The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family

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1. scibot 13 Jan 2020
  
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  RRID:AB_10691557
  
  DOI: 10.1016/j.celrep.2019.11.005
  
  Resource: (Cell Signaling Technology Cat# 2724, RRID:AB_10691557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10691557
  
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  RRID:AB_10691557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719314767
Nov 2018
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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

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1. scibot 05 Nov 2018
  
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  RRID:AB_10691557
  
  Curator: @anp055
  
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  (Cell Signaling Technology Cat# 2724S, RRID:AB_10691557)
  
  SciCrunch record: RRID:AB_10691557
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_10691557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627317309030