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Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function

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Jan 2026
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Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer

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Dec 2025
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CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

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Nov 2025
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Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding

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pmc.ncbi.nlm.nih.gov/articles/PMC12631751/
Aug 2025
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AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12355176/
Jul 2025
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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Apr 2025
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CD3xHER2 bsAb-Mediated Activation of Resting T-cells at HER2 Positive Tumor Clusters Is Sufficient to Trigger Bystander Eradication of Distant HER2 Negative Clusters Through IFNγ and TNFα

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Feb 2025
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BPS Publications

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  DOI: 10.1111/bph.17463
  
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Jan 2025
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Steroid hormone receptors, exome sequencing and treatment responsiveness of breast cancer patient-derived xenografts originated in a South American country

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pmc.ncbi.nlm.nih.gov/articles/PMC11742900/
Aug 2024
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CD3-engaging bispecific antibodies trigger a paracrine regulated wave of T-cell recruitment for effective tumor killing

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ncbi.nlm.nih.gov/pmc/articles/PMC11322607/
Jul 2024
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Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles

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HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice

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1. scibot 12 Jul 2024
  
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  DOI: 10.3390/ijms25137475
  
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Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance

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May 2024
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Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer

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  DOI: 10.1038/s41416-024-02697-5
  
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nature.com/articles/s41416-024-02697-5
Apr 2024
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AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer

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1. scibot 19 Apr 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-1459
  
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aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
Feb 2024
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway

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pmc.ncbi.nlm.nih.gov/articles/PMC10897550/
Dec 2023
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EGFR-activated myofibroblasts promote metastasis of pancreatic cancer

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B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling

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sciencedirect.com/science/article/pii/S1535610823003999
Apr 2023
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A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression

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Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

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Mar 2023
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Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions

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Beneficial Effects of Mifepristone Treatment in Patients with Breast Cancer Selected by the Progesterone Receptor Isoform Ratio: Results from the MIPRA Trial

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Feb 2023
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Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation

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Dec 2022
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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition

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Nov 2022
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Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling

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CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

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Aug 2022
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ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain

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May 2022
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A human breast atlas integrating single-cell proteomics and transcriptomics

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Apr 2022
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Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis

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ADAM17 regulates p75NTR–mediated fibrinolysis and nerve remyelination

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jneurosci.org/content/42/12/2433
Jan 2022
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Triple targeting of breast tumors driven by hormonal receptors and HER2

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  DOI: 10.1158/1535-7163.MCT-21-0098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
Aug 2021
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Untitled document

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  DOI: 10.7554/eLife.29241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5589416/
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Untitled document

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  DOI: 10.1210/js.2018-00170
  
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academic.oup.com/jes/article/2/12/1381/5126391
Jun 2021
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Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans

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Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function

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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex

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Genome oligopaint via local denaturation fluorescence in situ hybridization

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Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer

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Autophagy blockade limits HER2+ breast cancer tumorigenesis by perturbing HER2 trafficking and promoting release via small extracellular vesicles

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Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

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BPS Publications

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Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers

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HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line

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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

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Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

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CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

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js.2018-00170.pdf

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Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

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Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.

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Nov 2017
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Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

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