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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer
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  4. May 2024
  5. 52.53.155.43 52.53.155.43
    Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    GABAergic interneurons in the hippocampal CA1 mediate contextual fear generalization in PTSD rats
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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  9. Apr 2024
  10. dx.doi.org dx.doi.org
    Acute Exercise Increases GDF15 and Unfolded Protein Response/Integrated Stress Response in Muscle in Type 2 diabetes
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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  12. Mar 2024
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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  14. Feb 2024
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    The HRI branch of the integrated stress response selectively triggers mitophagy
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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  17. Jan 2024
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    Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells
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  19. Dec 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
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  21. Nov 2023
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    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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  25. Aug 2023
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    Lysosomal cystine governs ferroptosis sensitivity in cancer via cysteine stress response
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
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  29. Jul 2023
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    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
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  32. Jun 2023
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    Brief Oxygen Exposure after Traumatic Brain Injury Hastens Recovery and Promotes Adaptive Chronic Endoplasmic Reticulum Stress Responses
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    A mitochondrial iron-responsive pathway regulated by DELE1
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  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic deletion of protein kinase R-like ER kinase (PERK) does not affect learning and memory in aged mice but worsens outcome from experimental stroke
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  36. Apr 2023
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    SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions
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  38. Dec 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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  40. Oct 2022
  41. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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      DOI: 10.7554/eLife.81083

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  42. Sep 2022
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    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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  44. Aug 2022
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    Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
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  46. Jul 2022
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    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
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    Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis
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  49. Apr 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
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      DOI: 10.7554/eLife.76963

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    ncbi.nlm.nih.gov/pmc/articles/PMC9007586/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
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      DOI: 10.1158/1541-7786.MCR-21-0374

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
  52. Mar 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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  54. Feb 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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  56. Jan 2022
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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      DOI: 10.1016/j.ccell.2021.12.009

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  58. Nov 2021
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  64. Sep 2021
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    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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  109. Nov 2017
  110. academic.oup.com academic.oup.com
    Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response
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    1. scibot 08 Nov 2017
      AB_10692650

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    academic.oup.com/endo/article/158/10/3162/4083504/Angiotensin-II-Causes-Cell-Dysfunction-Through-an
  111. academic.oup.com academic.oup.com
    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis
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    1. scibot 08 Nov 2017
      AB_10692650

      Curator: @bandrow

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    academic.oup.com/endo/article/158/6/1659/3058741/Guanabenz-Sensitizes-Pancreatic-Cells-to-Lipotoxic
  112. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    1. scibot 08 Nov 2017
      AB_10692650

      Curator: @kaitlinsung

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      RRID:AB_10692650 RRIDCUR:Validated
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    elifesciences.org/content/6/e22871
  113. www.sciencedirect.com www.sciencedirect.com
    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
    1
    1. scibot 08 Nov 2017
      AB_10692650

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 5324, RRID:AB_10692650)

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      RRID:AB_10692650 RRIDCUR:Validated
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