78 Matching Annotations
  1. Apr 2024
  2. dx.doi.org dx.doi.org
    Acute Exercise Increases GDF15 and Unfolded Protein Response/Integrated Stress Response in Muscle in Type 2 diabetes
    1
    1. scibot 04 Apr 2024
      RRID:AB_10692650

      DOI: 10.1210/clinem/dgae032

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    dx.doi.org/10.1210/clinem/dgae032
  3. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  4. Mar 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
    2
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113900

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    2. scibot 12 Mar 2024
      RRID:AB_10692650

      DOI: 10.1016/j.celrep.2024.113900

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    sciencedirect.com/science/article/pii/S2211124724002286
  6. Feb 2024
  7. www.sciencedirect.com www.sciencedirect.com
    The HRI branch of the integrated stress response selectively triggers mitophagy
    3
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.016

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    2. scibot 14 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.016

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    3. scibot 13 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.016

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    sciencedirect.com/science/article/pii/S1097276524000522
  8. www.sciencedirect.com www.sciencedirect.com
    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.008

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    sciencedirect.com/science/article/pii/S1097276524000091
  9. Jan 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113615

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    sciencedirect.com/science/article/pii/S2211124723016273
  11. Dec 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
    1
    1. scibot 13 Dec 2023
      RRID:AB_10692650

      DOI: 10.1158/2767-9764.CRC-23-0350

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    ncbi.nlm.nih.gov/pmc/articles/PMC10704957/
  13. Nov 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
    1
    1. scibot 30 Nov 2023
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      DOI: 10.1038/s41467-023-43175-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
    2
    1. scibot 11 Nov 2023
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      DOI: 10.1097/BS9.0000000000000168

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    2. scibot 11 Nov 2023
      AB_10692650

      DOI: 10.1097/BS9.0000000000000168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  17. Aug 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Lysosomal cystine governs ferroptosis sensitivity in cancer via cysteine stress response
    1
    1. scibot 30 Aug 2023
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      DOI: 10.1016/j.molcel.2023.08.004

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    sciencedirect.com/science/article/abs/pii/S1097276523006408
  19. www.sciencedirect.com www.sciencedirect.com
    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
    1
    1. scibot 18 Aug 2023
      RRID:AB_10692650

      DOI: 10.1016/j.celrep.2023.112986

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    sciencedirect.com/science/article/pii/S221112472300997X
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
    1
    1. scibot 03 Aug 2023
      RRID:AB_10692650

      DOI: 10.1016/j.cmet.2023.07.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC10432853/
  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
    1
    1. scibot 12 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112746

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    sciencedirect.com/science/article/pii/S221112472300757X
  23. www.sciencedirect.com www.sciencedirect.com
    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
    2
    1. scibot 08 Jul 2023
      RRID:AB_10692650

      DOI: 10.1016/j.celrep.2023.112764

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    2. scibot 08 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112764

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    sciencedirect.com/science/article/pii/S2211124723007751
  24. Jun 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brief Oxygen Exposure after Traumatic Brain Injury Hastens Recovery and Promotes Adaptive Chronic Endoplasmic Reticulum Stress Responses
    1
    1. scibot 30 Jun 2023
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      DOI: 10.3390/ijms24129831

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    ncbi.nlm.nih.gov/pmc/articles/PMC10298247/
  26. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial iron-responsive pathway regulated by DELE1
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.031

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    sciencedirect.com/science/article/pii/S1097276523004136
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic deletion of protein kinase R-like ER kinase (PERK) does not affect learning and memory in aged mice but worsens outcome from experimental stroke
    1
    1. scibot 15 Jun 2023
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      DOI: 10.1002/jnr.25224

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    onlinelibrary.wiley.com/doi/10.1002/jnr.25224
  28. Apr 2023
  29. link.springer.com link.springer.com
    SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions
    1
    1. scibot 01 Apr 2023
      RRID:AB_10692650

      DOI: 10.1186/s12985-023-02021-2

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    link.springer.com/article/10.1186/s12985-023-02021-2
  30. Dec 2022
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
    1
    1. scibot 08 Dec 2022
      RRID:AB_10692650

      DOI: 10.1016/j.isci.2022.105626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  32. Oct 2022
  33. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
    1
    1. scibot 19 Oct 2022
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      DOI: 10.7554/eLife.81083

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    elifesciences.org/articles/81083
  34. Sep 2022
  35. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
    1
    1. scibot 13 Sep 2022
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      DOI: 10.1016/j.xcrm.2022.100741

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    sciencedirect.com/science/article/pii/S2666379122002907
  36. Aug 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
    1
    1. scibot 10 Aug 2022
      RRID:AB_10694803

      DOI: 10.1016/j.celrep.2022.111178

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    sciencedirect.com/science/article/pii/S2211124722009913
  38. Jul 2022
  39. www.sciencedirect.com www.sciencedirect.com
    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
    1
    1. scibot 15 Jul 2022
      RRID:AB_10692650

      DOI: 10.1016/j.cmet.2022.06.010

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    sciencedirect.com/science/article/pii/S1550413122002303
  40. www.sciencedirect.com www.sciencedirect.com
    Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis
    1
    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.stem.2022.06.004

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    sciencedirect.com/science/article/pii/S1934590922002533
  41. Apr 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
    1
    1. scibot 15 Apr 2022
      RRID:AB_10692650

      DOI: 10.7554/eLife.76963

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    ncbi.nlm.nih.gov/pmc/articles/PMC9007586/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
    1
    1. scibot 08 Apr 2022
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      DOI: 10.1158/1541-7786.MCR-21-0374

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
  44. Mar 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
    1
    1. scibot 26 Mar 2022
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      DOI: 10.1016/j.molcel.2022.02.031

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    sciencedirect.com/science/article/pii/S1097276522002052
  46. Feb 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
    1
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      DOI: 10.1016/j.isci.2022.103859

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    sciencedirect.com/science/article/pii/S2589004222001298
  48. Jan 2022
  49. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
    1
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      DOI: 10.1016/j.ccell.2021.12.009

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    sciencedirect.com/science/article/pii/S1535610821006620
  50. Nov 2021
  51. academic.oup.com academic.oup.com
    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
    1
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      DOI: 10.1210/endocr/bqab212

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    academic.oup.com/endo/article/163/1/bqab212/6382455
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC1A5 provides glutamine and asparagine necessary for bone development in mice
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.71595

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553342/
  53. Oct 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
    1
    1. scibot 02 Oct 2021
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      DOI: 10.7554/eLife.66278

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478418/
  55. academic.oup.com academic.oup.com
    Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity
    1
    1. scibot 01 Oct 2021
      RRID:AB_10692650

      DOI: 10.1210/clinem/dgab680

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab680/6370132
  56. Sep 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109742

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    sciencedirect.com/science/article/pii/S2211124721011955
  58. journals.sagepub.com journals.sagepub.com
    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    1. scibot 16 Sep 2021
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      DOI: 10.1177/17590914211033650

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  59. Aug 2021
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    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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  65. Jul 2021
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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  70. May 2021
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  75. Feb 2021
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    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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  77. Oct 2020
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  79. Sep 2020
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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  93. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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  101. Nov 2017
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    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis
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    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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