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  1. Last 7 days
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    Multiomic characterization of microsatellite-stable colorectal cancer reveals distinct biology and targetable vulnerabilities
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    sciencedirect.com/science/article/pii/S1535610826004332
  3. May 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Premature cleavage and polyadenylation in the minor intron of PTEN modulate its expression and generate a functional long non-coding RNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC13141466/
  5. Apr 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056290/
  7. Feb 2026
  8. dx.doi.org dx.doi.org
    PTEN status on gonadotropin-releasing hormone (GnRH) metabolite, GnRH-(1-5), effects in endometrial cancer cell lines migration, & transcriptomic analysis of basal cell line and tumor gene expressions
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    dx.doi.org/10.1093/biolre/ioaf168
  9. Dec 2025
  10. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225027646-main-html.html
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  11. Jun 2025
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    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
  13. Jan 2025
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    PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    sciencedirect.com/science/article/pii/S0021925825000869
  15. Sep 2024
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    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    sciencedirect.com/science/article/pii/S1074761324004072
  17. Apr 2024
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    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
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    dx.doi.org/10.1210/endocr/bqae044
  19. Mar 2024
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    Epigenetic disruption of histone deacetylase-2 accelerated apoptotic signaling and retarded malignancy in gastric cells
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    futuremedicine.com/doi/10.2217/epi-2023-0350
  21. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    biorxiv.org/content/10.1101/2024.03.03.583221v1
  22. Feb 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
  24. Jan 2024
  25. www.nature.com www.nature.com
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    nature.com/articles/s41388-024-02947-z
  26. Nov 2023
  27. www.sciencedirect.com www.sciencedirect.com
    MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology
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    sciencedirect.com/science/article/pii/S2589004223021776
  28. Jul 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    ncbi.nlm.nih.gov/pmc/articles/PMC10327161/
  30. Jun 2023
  31. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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    nature.com/articles/s41417-023-00637-8
  32. May 2023
  33. aacrjournals.org aacrjournals.org
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer
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    aacrjournals.org/cancerres/article/82/13/2458/705024/Transcriptional-Repression-by-FoxM1-Suppresses
  34. Apr 2023
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  36. Jan 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9830446/
  38. Aug 2022
  39. 52.53.155.43 52.53.155.43
    Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas
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  40. May 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595717/
  42. Feb 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8797319/
  44. Dec 2021
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses
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    onlinelibrary.wiley.com/doi/10.1002/advs.202103360
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  47. Nov 2021
  48. www.sciencedirect.com www.sciencedirect.com
    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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    sciencedirect.com/science/article/pii/S2211124721014121
  49. Aug 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
  51. Jul 2021
  52. jcs.biologists.org jcs.biologists.org
    The Parkinson's gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3
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    jcs.biologists.org/content/132/20/jcs233221
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
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    sciencedirect.com/science/article/pii/S1535610820305432
  55. Feb 2021
  56. mct.aacrjournals.org mct.aacrjournals.org
    Predictive and Pharmacodynamic Biomarkers of Response to the Phosphatidylinositol 3-Kinase Inhibitor Taselisib in Breast Cancer Preclinical Models
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    mct.aacrjournals.org/content/19/1/292
  57. Sep 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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    sciencedirect.com/science/article/pii/S153561082030427X
  59. www.sciencedirect.com www.sciencedirect.com
    Tau Reduction Prevents Key Features of Autism in Mouse Models
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    sciencedirect.com/science/article/pii/S0896627320300659
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of metabotropic glutamate receptor 4 regulates proliferation and neural differentiation in neural stem/progenitor cells of the rat subventricular zone and increases phosphatase and tensin homolog protein expression
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14984
  61. academic.oup.com academic.oup.com
    Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice
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    academic.oup.com/endo/article/161/4/bqz007/5805123
  62. Nov 2018
  63. academic.oup.com academic.oup.com
    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
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    academic.oup.com/endo/article/159/6/2421/4990770
  64. Nov 2017
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  66. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    sciencedirect.com/science/article/pii/S2405471216304082