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FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
Apr 2026
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Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway

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Mar 2026
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USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis

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Rapamycin Reduces Amyloid‐β Plaques and Improves Behavioral Performance in a Sex‐Dependent Manner in Mouse Models of Amyloidosis

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Feb 2026
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KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression

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Jan 2026
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METTL3 regulates α-KG-dependent mitophagy and apoptosis in nucleus pulposus cells through the MALAT1/miR-23c/IDH1 axis

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sciencedirect.com/science/article/pii/S2211124725015657
Dec 2025
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Post-translational switch of DHCR24 acetylation sustains sterol synthesis and promotes HCC via the 7-ketocholesterol/p62 axis

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sciencedirect.com:5037/science/article/pii/S2211124725014123
Nov 2025
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Parkinson’s disease modeling in regenerative spiny mice (Acomys dimidiatus) captures key disease-relevant behavioral, histological, and molecular signatures

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1. scibot 13 Nov 2025
  
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biorxiv.org/content/10.1101/2025.11.06.687049v1
Aug 2025
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41467_2025_56346_MOESM1_ESM-html.html

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52.53.155.43/0cdd1395338fbad58a2c837457ae32b83153d0d5/41467_2025_56346_MOESM1_ESM-html.html
Jul 2025
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41467_2025_56346_MOESM1_ESM (1)-html.html

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Genetic perturbation of cellular homeostasis regulates integrated stress response signaling to control Drosophila hematopoiesis

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TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy

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Jun 2025
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PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling

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May 2025
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Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets

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Mar 2025
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Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death

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7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death

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Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia

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pmc.ncbi.nlm.nih.gov/articles/PMC12021055/
Dec 2024
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Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1

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cell.com/cell-metabolism/fulltext/S1550-4131(24)00413-3
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TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination

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The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

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Jul 2024
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Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway

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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

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The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence

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ncbi.nlm.nih.gov/pmc/articles/PMC11240082/
May 2024
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Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy

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  DOI: 10.1111/jnc.16126
  
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Apr 2024
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AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis

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ncbi.nlm.nih.gov/pmc/articles/PMC10981016/
Mar 2024
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RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation

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A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

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  DOI: 10.1016/j.molcel.2024.02.019
  
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Feb 2024
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Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis

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  DOI: 10.1016/j.celrep.2024.113846
  
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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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  DOI: 10.1016/j.celrep.2024.113769
  
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sciencedirect.com/science/article/pii/S2211124724000974
Dec 2023
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NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

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1. scibot 22 Dec 2023
  
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  DOI: 10.1038/s41467-023-44033-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
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Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy

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1. scibot 08 Dec 2023
  
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  DOI: 10.1007/s10753-023-01940-0
  
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Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia

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SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

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SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1

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Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia

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Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis

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Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia

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Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy

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ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway

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The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence

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Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABAA receptor transport in a murine model

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May 2023
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FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis

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Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex

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Jan 2023
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Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia

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Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis

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Beclin1 Deficiency Suppresses Epileptic Seizures

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Apr 2022
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Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control

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Mar 2022
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Bradykinin postconditioning protects rat hippocampal... : Neural Regeneration Research

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Feb 2022
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Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions

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Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

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BPS Publications

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Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter

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Jul 2021
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Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats

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Untitled document

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Delivering progranulin to neuronal lysosomes protects against excitotoxicity

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Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination

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Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans

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The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells

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Jan 2021
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Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy

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Oct 2020
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The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

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Sep 2020
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Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress

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Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34

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Nov 2018
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mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux

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iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding

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sciencedirect.com/science/article/pii/S1535610817304129
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Prion-like transmission of α-synuclein pathology in the context of an NFL null background

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1. scibot 05 Nov 2018
  
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  RRID:AB_10694431
  
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sciencedirect.com/science/article/pii/S0304394017308066
Nov 2017
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Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells

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1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276517306536
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Systematic Characterization of Autophagy in Gestational Diabetes Mellitus

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1. scibot 08 Nov 2017
  
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  AB_10694431
  
  Curator: @patriciaelyse_
  
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academic.oup.com/endo/article/158/8/2522/3805448/Systematic-Characterization-of-Autophagy-in

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