29 Matching Annotations
  1. Dec 2024
  2. www.nature.com www.nature.com
    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
    1
    1. scibot 24 Dec 2024
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      DOI: 10.1038/s41418-024-01439-7

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    nature.com/articles/s41418-024-01439-7
  3. Jan 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers
    1
    1. scibot 19 Jan 2024
      RRID:AB_10694494

      DOI: 10.1158/2767-9764.CRC-23-0275

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    ncbi.nlm.nih.gov/pmc/articles/PMC10793200/
  5. Nov 2023
  6. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
    1
    1. scibot 25 Nov 2023
      RRID:AB_10694494

      DOI: 10.1038/s41388-023-02892-3

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    nature.com/articles/s41388-023-02892-3
  7. Sep 2023
  8. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
    1. scibot 19 Sep 2023
      RRID:AB_10694494

      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  9. Jun 2023
  10. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    1
    1. scibot 24 Jun 2023
      RRID:AB_10694494

      DOI: 10.1038/s41467-023-39241-7

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    nature.com/articles/s41467-023-39241-7
  11. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
      RRID:AB_10694494

      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  12. Apr 2023
  13. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
    1
    1. scibot 08 Apr 2023
      RRID:AB_10694494

      DOI: 10.1016/j.xcrm.2023.101007

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    sciencedirect.com/science/article/pii/S2666379123001179
  14. www.sciencedirect.com www.sciencedirect.com
    Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
    1
    1. scibot 06 Apr 2023
      RRID:AB_10694494

      DOI: 10.1016/j.celrep.2023.112324

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    sciencedirect.com/science/article/pii/S2211124723003352
  15. Feb 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Piperlongumine conjugates induce targeted protein degradation
    1
    1. scibot 09 Feb 2023
      RRID:AB_10694494

      DOI: 10.1016/j.chembiol.2023.01.004

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    sciencedirect.com/science/article/pii/S2451945623000272
  17. Nov 2022
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
    1
    1. scibot 18 Nov 2022
      RRID:AB_10694494

      DOI: 10.1016/j.isci.2022.105458

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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  19. Jun 2022
  20. www.sciencedirect.com www.sciencedirect.com
    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
    1
    1. scibot 29 Jun 2022
      RRID:AB_10694494

      DOI: 10.1016/j.celrep.2022.111019

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    sciencedirect.com/science/article/pii/S2211124722008087
  21. Apr 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
    1
    1. scibot 21 Apr 2022
      RRID:AB_10694494

      DOI: 10.1016/j.devcel.2022.03.019

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    sciencedirect.com/science/article/pii/S1534580722002295
  23. Feb 2022
  24. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
    2
    1. scibot 11 Feb 2022
      RRID:AB_10694494

      DOI: 10.1016/j.immuni.2022.01.003

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    2. scibot 09 Feb 2022
      RRID:AB_10694494

      DOI: 10.1016/j.immuni.2022.01.003

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    pubmed.ncbi.nlm.nih.gov/35139355/
  25. Nov 2021
  26. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      RRID:AB_10694494

      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
  27. Aug 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
    1
    1. scibot 18 Aug 2021
      RRID:AB_10694494

      DOI: 10.1016/j.devcel.2021.07.019

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    sciencedirect.com/science/article/pii/S153458072100602X
  29. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
      RRID:AB_10694494

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  30. www.sciencedirect.com www.sciencedirect.com
    Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition
    1
    1. scibot 06 Aug 2021
      RRID:AB_10694494

      DOI: 10.1016/j.molcel.2021.06.032

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    sciencedirect.com/science/article/pii/S1097276521005438
  31. Jul 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.celrep.2018.10.103

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    sciencedirect.com/science/article/pii/S221112471831725X
  33. May 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
    1
    1. scibot 12 May 2021
      RRID:AB_10694494

      DOI: 10.1016/j.immuni.2021.04.012

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    sciencedirect.com/science/article/pii/S1074761321001746
  35. www.sciencedirect.com www.sciencedirect.com
    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
    1
    1. scibot 07 May 2021
      RRID:AB_10694494

      DOI: 10.1016/j.jconrel.2021.03.015

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    sciencedirect.com/science/article/pii/S0168365921001267
  36. Apr 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    1. scibot 22 Apr 2021
      RRID:AB_10694494

      DOI: 10.1016/j.ccell.2020.10.010

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    sciencedirect.com/science/article/pii/S1535610820305419
  38. Sep 2020
  39. mcr.aacrjournals.org mcr.aacrjournals.org
    Ceramide analog SACLAC modulates sphingolipid levels and Mcl-1 splicing to induce apoptosis in acute myeloid leukemia
    1
    1. scibot 14 Sep 2020
      AB_10694494

      DOI: 10.1158/1541-7786.MCR-19-0619

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    mcr.aacrjournals.org/content/18/3/352
  40. Jan 2020
  41. www.mdpi.com www.mdpi.com
    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
    1
    1. scibot 13 Jan 2020
      RRID:AB_10694494

      DOI: 10.3390/cancers11101456

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    mdpi.com/2072-6694/11/10/1456
  42. www.sciencedirect.com www.sciencedirect.com
    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
    1
    1. scibot 13 Jan 2020
      RRID:AB_10694494

      DOI: 10.1016/j.molcel.2019.06.040

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1097276519304976
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Jan 2020
      RRID:AB_10694494

      DOI: 10.1111/bph.14773

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    bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14773
  44. Nov 2018
  45. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818301831
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5650077/