38 Matching Annotations
  1. Jun 2024
  2. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
    1
    1. scibot 29 Jun 2024
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      DOI: 10.1016/j.isci.2024.109978

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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    ol_28_1_14449_PDF-html.html
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    1. scibot 17 May 2024
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      DOI: 10.3892/ol.2024.14449

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    52.53.155.43/917364cd3fceb398a38ff7cf2bbe2411971526ce/ol_28_1_14449_PDF-html.html
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
    1
    1. scibot 15 May 2024
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      DOI: 10.3389/fimmu.2024.1355130

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    ncbi.nlm.nih.gov/pmc/articles/PMC11089195/
  6. Apr 2024
  7. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
    1. scibot 25 Apr 2024
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      DOI: 10.1083/jcb.202303141

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    2. scibot 25 Apr 2024
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      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
  8. www.sciencedirect.com www.sciencedirect.com
    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
    2
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114064

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    2. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114064

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    sciencedirect.com/science/article/pii/S2211124724003929
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
    2
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113975

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    2. scibot 22 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113975

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    sciencedirect.com/science/article/pii/S2211124724003036
  11. Feb 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
    1
    1. scibot 08 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.isci.2023.108659

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    sciencedirect.com/science/article/pii/S2589004223027360
  15. Nov 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1158/1078-0432.CCR-23-0103

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618648/
  17. Oct 2023
  18. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1158/1078-0432.ccr-23-0103

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  19. Aug 2023
  20. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1158/1078-0432.ccr-23-0103

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  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.025

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    sciencedirect.com/science/article/pii/S1097276523004720
  23. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    1. scibot 08 Jul 2023
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      DOI: 10.1158/1078-0432.ccr-23-0103

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  24. Jun 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Detection of endogenous translesion DNA synthesis in single mammalian cells
    1
    1. scibot 22 Jun 2023
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      DOI: 10.1016/j.crmeth.2023.100501

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    sciencedirect.com/science/article/pii/S2667237523001303
  26. Apr 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
    1
    1. scibot 04 Apr 2023
      RRID:AB_10694556

      DOI: 10.1152/ajplung.00408.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8957349/
  28. Dec 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
    1
    1. scibot 16 Dec 2022
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      DOI: 10.1126/sciadv.abq0648

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    ncbi.nlm.nih.gov/pmc/articles/PMC9733930/
  30. www.science.org www.science.org
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
    1
    1. scibot 13 Dec 2022
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      DOI: 10.1126/sciadv.abq0648

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    science.org/doi/10.1126/sciadv.abq0648
  31. Nov 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
  33. May 2022
  34. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
    1
    1. scibot 05 May 2022
      RRID:AB_10694556

      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  35. Aug 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype
    1
    1. scibot 09 Aug 2021
      RRID:AB_10694556

      DOI: 10.1016/j.stem.2018.10.011

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    sciencedirect.com/science/article/pii/S1934590918304922
  37. www.embopress.org www.embopress.org
    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
    1
    1. scibot 06 Aug 2021
      RRID:AB_10694556

      DOI: 10.15252/embj.2020107413

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    embopress.org/doi/abs/10.15252/embj.2020107413
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.stem.2018.10.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224657/
  39. Jun 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
    1
    1. scibot 16 Jun 2021
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      DOI: 10.3390/cancers13112840

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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  41. May 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
    1
    1. scibot 10 May 2021
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      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  43. Jan 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
    1
    1. scibot 27 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108680

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    sciencedirect.com/science/article/pii/S2211124720316697
  45. Dec 2020
  46. www.cell.com www.cell.com
    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
    1
    1. scibot 10 Dec 2020
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      DOI: 10.1016/j.molcel.2020.10.016

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
  47. Oct 2020
  48. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
    1
    1. scibot 08 Oct 2020
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      DOI: 10.1016/j.celrep.2020.108221

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    pubmed.ncbi.nlm.nih.gov/33027668/
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
    1
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      DOI: 10.1016/j.cmet.2019.11.002

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    sciencedirect.com/science/article/pii/S1550413119306096
  51. www.sciencedirect.com www.sciencedirect.com
    The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis
    1
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      DOI: 10.1016/j.cub.2019.11.064

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    sciencedirect.com/science/article/pii/S0960982219315660
  52. www.sciencedirect.com www.sciencedirect.com
    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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      DOI: 10.1016/j.molcel.2019.10.008

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    sciencedirect.com/science/article/pii/S1097276519307683
  53. link.springer.com link.springer.com
    Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity
    1
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      DOI: 10.1007/s10495-019-01529-9

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    link.springer.com/article/10.1007/s10495-019-01529-9
  54. www.sciencedirect.com www.sciencedirect.com
    FXR Regulates Intestinal Cancer Stem Cell Proliferation
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      DOI: 10.1016/j.cell.2019.01.036

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    sciencedirect.com/science/article/pii/S0092867419300996
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1934590918304855
  57. Nov 2017
  58. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
    1
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306184
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two subunits of human ORC are dispensable for DNA replication and proliferation
    1
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