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  1. Last 7 days
  2. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
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    1. scibot 25 Apr 2024
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      DOI: 10.1083/jcb.202303141

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      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    1. scibot 09 Apr 2024
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    2. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003929
  5. Mar 2024
  6. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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    1. scibot 22 Mar 2024
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    2. scibot 22 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003036
  7. Feb 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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    1. scibot 08 Feb 2024
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  9. Dec 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.isci.2023.108659

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    sciencedirect.com/science/article/pii/S2589004223027360
  11. Nov 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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    1. scibot 03 Nov 2023
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      DOI: 10.1158/1078-0432.CCR-23-0103

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618648/
  13. Oct 2023
  14. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
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    1. scibot 07 Oct 2023
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  15. Aug 2023
  16. 52.53.155.43 52.53.155.43
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    1. scibot 11 Aug 2023
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  17. Jul 2023
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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    1. scibot 21 Jul 2023
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  19. 52.53.155.43 52.53.155.43
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    1. scibot 08 Jul 2023
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  20. Jun 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Detection of endogenous translesion DNA synthesis in single mammalian cells
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    1. scibot 22 Jun 2023
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      DOI: 10.1016/j.crmeth.2023.100501

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    sciencedirect.com/science/article/pii/S2667237523001303
  22. Apr 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
    1
    1. scibot 04 Apr 2023
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      DOI: 10.1152/ajplung.00408.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8957349/
  24. Dec 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
    1
    1. scibot 16 Dec 2022
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      DOI: 10.1126/sciadv.abq0648

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    ncbi.nlm.nih.gov/pmc/articles/PMC9733930/
  26. www.science.org www.science.org
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
    1
    1. scibot 13 Dec 2022
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      DOI: 10.1126/sciadv.abq0648

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  27. Nov 2022
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    Autophagy promotes cell survival by maintaining NAD levels
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    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
  29. May 2022
  30. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    1. scibot 05 May 2022
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      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  31. Aug 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype
    1
    1. scibot 09 Aug 2021
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      DOI: 10.1016/j.stem.2018.10.011

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    sciencedirect.com/science/article/pii/S1934590918304922
  33. www.embopress.org www.embopress.org
    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
    1
    1. scibot 06 Aug 2021
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      DOI: 10.15252/embj.2020107413

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    embopress.org/doi/abs/10.15252/embj.2020107413
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.stem.2018.10.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224657/
  35. Jun 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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      DOI: 10.3390/cancers13112840

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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  37. May 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  39. Jan 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
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    1. scibot 27 Jan 2021
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    sciencedirect.com/science/article/pii/S2211124720316697
  41. Dec 2020
  42. www.cell.com www.cell.com
    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
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    1. scibot 10 Dec 2020
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
  43. Oct 2020
  44. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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      DOI: 10.1016/j.celrep.2020.108221

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  45. Jan 2020
  46. www.sciencedirect.com www.sciencedirect.com
    Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
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      DOI: 10.1016/j.cmet.2019.11.002

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    sciencedirect.com/science/article/pii/S1550413119306096
  47. www.sciencedirect.com www.sciencedirect.com
    The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis
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      DOI: 10.1016/j.cub.2019.11.064

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    sciencedirect.com/science/article/pii/S0960982219315660
  48. www.sciencedirect.com www.sciencedirect.com
    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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      DOI: 10.1016/j.molcel.2019.10.008

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    sciencedirect.com/science/article/pii/S1097276519307683
  49. link.springer.com link.springer.com
    Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity
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      DOI: 10.1007/s10495-019-01529-9

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    link.springer.com/article/10.1007/s10495-019-01529-9
  50. www.sciencedirect.com www.sciencedirect.com
    FXR Regulates Intestinal Cancer Stem Cell Proliferation
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      DOI: 10.1016/j.cell.2019.01.036

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    sciencedirect.com/science/article/pii/S0092867419300996
  51. Nov 2018
  52. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1934590918304855
  53. Nov 2017
  54. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306184
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two subunits of human ORC are dispensable for DNA replication and proliferation
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