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Multiomic characterization of microsatellite-stable colorectal cancer reveals distinct biology and targetable vulnerabilities

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1. scibot 24 Oct 2026
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.ccell.2026.09.014
  
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sciencedirect.com/science/article/pii/S1535610826004332
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CerS2 is a druggable target in triple-negative breast cancer

1
1. scibot 22 Oct 2026
  
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  RRID:AB_10694844
  
  DOI: 10.1158/1535-7163.MCT-25-1159
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13678703/
Jun 2026
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IL-4/IL-13 signaling suppresses ABT-263-induced apoptosis in senescent human fibroblasts

1
1. scibot 04 Jun 2026
  
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  AB_10694844
  
  DOI: 10.1016/j.intimp.2026.116939
  
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sciencedirect.com/science/article/pii/S156757692600785X
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Raspberry Polyphenols Target Molecular Pathways of Heart Failure

1
1. scibot 04 Feb 2026
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.jnutbio.2023.109535
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12862629/
Aug 2025
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Distinct microRNA signatures define sporadic PSP-RS and PD in patient-derived midbrain organoids

1
1. scibot 05 Aug 2025
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.isci.2025.113162
  
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sciencedirect.com/science/article/pii/S2589004225014233
Oct 2024
aacrjournals.org aacrjournals.org

YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma

1
1. scibot 02 Oct 2024
  
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  RRID:AB_10694844
  
  DOI: 10.1158/0008-5472.CAN-20-0025
  
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  Curator: @bandrow
  
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aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
Feb 2024
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Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis

1
1. scibot 08 Feb 2024
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.isci.2024.108883
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10838789/
Nov 2023
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Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.xcrm.2023.101290
  
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sciencedirect.com/science/article/pii/S2666379123004846
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer

1
1. scibot 31 Oct 2023
  
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  RRID:AB_10694844
  
  DOI: 10.3390/cancers15205082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10605716/
Apr 2023
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USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

1
1. scibot 08 Apr 2023
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.xcrm.2023.101007
  
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sciencedirect.com/science/article/pii/S2666379123001179
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression

2
1. scibot 19 Nov 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1158/2767-9764.crc-22-0024
  
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2. scibot 19 Nov 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1158/2767-9764.crc-22-0024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
Sep 2022
www.tandfonline.com www.tandfonline.com

Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis

1
1. scibot 16 Sep 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1080/15548627.2022.2100105
  
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tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
Aug 2022
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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

1
1. scibot 23 Aug 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.crmeth.2022.100271
  
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sciencedirect.com/science/article/pii/S2667237522001485
Jul 2022
aacrjournals.org aacrjournals.org

Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression

1
1. scibot 29 Jul 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1158/2767-9764.CRC-22-0024
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
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aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
Apr 2022
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Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

1
1. scibot 21 Apr 2022
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.devcel.2022.03.019
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
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sciencedirect.com/science/article/pii/S1534580722002295
Mar 2022
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F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells

1
1. scibot 18 Mar 2022
  
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  2762
  
  DOI: 10.1016/j.taap.2022.115973
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S0041008X22001181
Nov 2021
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer

1
1. scibot 24 Nov 2021
  
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  RRID:AB_10694844
  
  DOI: 10.1158/1078-0432.CCR-21-0818
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
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clincancerres.aacrjournals.org/content/27/21/5979
Aug 2021
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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

1
1. scibot 16 Aug 2021
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.ccell.2021.07.006
  
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sciencedirect.com/science/article/pii/S1535610821003834
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Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

1
1. scibot 04 Aug 2021
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.ccell.2018.11.005
  
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sciencedirect.com/science/article/pii/S1535610818305269
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

1
1. scibot 04 Aug 2021
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.cels.2016.11.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

1
1. scibot 27 Jul 2021
  
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  RRID: AB_10694844
  
  DOI: 10.1016/j.cels.2016.11.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
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Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

1
1. scibot 01 Jul 2021
  
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  2762
  
  DOI: 10.1016/j.biocel.2021.106028
  
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sciencedirect.com/science/article/pii/S1357272521001060
Oct 2020
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The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

1
1. scibot 07 Oct 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.celrep.2020.108230
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
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  RRIDCUR:Validated RRID:AB_10694844
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sciencedirect.com/science/article/pii/S2211124720312195
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

1
1. scibot 26 Sep 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1038/s41419-020-2589-7
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_10694844
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ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
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Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

1
1. scibot 10 Sep 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.immuni.2020.02.007
  
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  Curator: @ethanbadger
  
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  RRID:AB_10694844 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761320300789
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Synthesis, biological evaluation and toxicity of novel tetrandrine analogues

1
1. scibot 09 Sep 2020
  
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  Bcl-xL
  
  DOI: 10.1016/j.ejmech.2020.112810
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10694844
  
  Curator comments: Bcl-xL Antibody Cell Signaling Technology Cat# 2762
  
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  RRID:AB_10694844 RRIDCUR:Missing
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pubmed.ncbi.nlm.nih.gov/32942071/
Jan 2020
royalsocietypublishing.org royalsocietypublishing.org

Oncogenic MYC amplifies mitotic perturbations

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1098/rsob.190136
  
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  Curator: @Naa003
  
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  RRID:AB_10694844 RRIDCUR:Validated
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royalsocietypublishing.org/doi/full/10.1098/rsob.190136
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.celrep.2019.07.070
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
  Curator: @ethanbadger
  
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  RRID:AB_10694844 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112471930974X
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BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10694844
  
  DOI: 10.1016/j.ccell.2019.04.005
  
  Resource: (Cell Signaling Technology Cat# 2762, RRID:AB_10694844)
  
  Curator: @ethanbadger
  
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  RRID:AB_10694844 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819302004
Nov 2018
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Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10694844
  
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  (Cell Signaling Technology Cat# 2762S, RRID:AB_10694844)
  
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sciencedirect.com/science/article/pii/S1535610818300217
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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10694844
  
  Curator: @anp055
  
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  (Cell Signaling Technology Cat# 2762S, RRID:AB_10694844)
  
  SciCrunch record: RRID:AB_10694844
  
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  RRID:AB_10694844 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627317309030
Nov 2017
academic.oup.com academic.oup.com

Gestational Diabetes Alters Functions in Offspring’s Umbilical Cord Cells With Implications for Cardiovascular Health

1
1. scibot 08 Nov 2017
  
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  AB_10694844
  
  Curator: @chewbeccax
  
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  (Cell Signaling Technology Cat# 2762S, RRID:AB_10694844)
  
  SciCrunch record: RRID:AB_10694844
  
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  RRID:AB_10694844 RRIDCUR:Validated
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academic.oup.com/endo/article/158/7/2102/3743786/Gestational-Diabetes-Alters-Functions-in-Offspring
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

1
1. scibot 08 Nov 2017
  
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  AB_10694844
  
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  (Cell Signaling Technology Cat# 2762S, RRID:AB_10694844)
  
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scibot

URL

sciencedirect.com/science/article/pii/S2405471216304082