36 Matching Annotations
  1. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
      AB_10695148

      DOI: 10.1016/j.molcel.2024.02.032

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    sciencedirect.com/science/article/pii/S1097276524001758
  3. Feb 2024
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    Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113888

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    sciencedirect.com/science/article/pii/S221112472400216X
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    1. scibot 09 Feb 2024
      RRID:AB_10695148

      DOI: 10.1016/j.celrep.2024.113714

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    sciencedirect.com/science/article/pii/S2211124724000421
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101396

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    sciencedirect.com/science/article/pii/S2666379124000053
  7. Oct 2023
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
    1. scibot 12 Oct 2023
      RRID:AB_10695148

      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
  9. Jul 2023
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.007

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    sciencedirect.com/science/article/pii/S1097276523004306
  11. Apr 2023
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    Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.xgen.2023.100294

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    sciencedirect.com/science/article/pii/S2666979X23000605
  13. Dec 2022
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    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111727

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    sciencedirect.com/science/article/pii/S2211124722016059
  15. Sep 2022
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    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
    1
    1. scibot 15 Sep 2022
      RRID:AB_10695148

      DOI: 10.1016/j.isci.2022.105013

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    sciencedirect.com/science/article/pii/S2589004222012858
  17. Jun 2022
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    Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
    1
    1. scibot 18 Jun 2022
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      DOI: 10.1016/j.molcel.2022.05.023

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    sciencedirect.com/science/article/pii/S1097276522004907
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis-Associated Colorectal Cancer
    1
    1. scibot 18 Jun 2022
      AB_10

      DOI: 10.1002/advs.202200536

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    ncbi.nlm.nih.gov/pmc/articles/PMC9376751/
  20. May 2022
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
    1
    1. scibot 25 May 2022
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      DOI: 10.1016/j.cell.2022.04.034

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    sciencedirect.com/science/article/pii/S0092867422005323
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
    1
    1. scibot 11 May 2022
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      DOI: 10.1016/j.celrep.2022.110788

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    sciencedirect.com/science/article/pii/S2211124722005551
  23. Apr 2022
  24. www.nature.com www.nature.com
    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
    1
    1. scibot 12 Apr 2022
      RRID:AB_10695148

      DOI: 10.1038/s41418-022-00983-4

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    nature.com/articles/s41418-022-00983-4
  25. Mar 2022
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    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
    1
    1. scibot 31 Mar 2022
      RRID:AB_10695148

      DOI: 10.1016/j.celrep.2022.110603

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    sciencedirect.com/science/article/pii/S2211124722003515
  27. Jan 2022
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    Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.neuron.2021.12.019

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    sciencedirect.com/science/article/pii/S0896627321010369
  29. Dec 2021
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.67952

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
  31. Nov 2021
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    CUT&Tag-BS for simultaneous profiling of histone modification and DNA methylation with high efficiency and low cost
    1
    1. scibot 16 Nov 2021
      5326S

      DOI: 10.1016/j.crmeth.2021.100118

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    sciencedirect.com/science/article/pii/S266723752100182X
  33. Sep 2021
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    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  35. Jul 2021
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    Establishment, maintenance, and recall of inflammatory memory
    1
    1. scibot 30 Jul 2021
      RRID:AB_10695148

      DOI: 10.1016/j.stem.2021.07.001

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    sciencedirect.com/science/article/pii/S1934590921002861
  37. May 2021
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    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
    1
    1. scibot 08 May 2021
      RRID:AB_10695148

      DOI: 10.1016/j.molcel.2021.03.008

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    sciencedirect.com/science/article/pii/S1097276521001763
  39. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
    1
    1. scibot 20 Apr 2021
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      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
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      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
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    MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity
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    1. scibot 13 Apr 2021
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      DOI: 10.1038/s41419-021-03647-2

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    nature.com/articles/s41419-021-03647-2
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
    1. scibot 02 Apr 2021
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      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
  44. Sep 2020
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    The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
    1
    1. scibot 16 Sep 2020
      RRID:AB_10695148

      DOI: 10.1016/j.celrep.2020.107548

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    sciencedirect.com/science/article/pii/S2211124720304587
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    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
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      DOI: 10.1016/j.ccell.2020.03.005

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    sciencedirect.com/science/article/pii/S1535610820301069
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    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
    1
    1. scibot 12 Sep 2020
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      DOI: 10.1016/j.molcel.2020.03.010

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    sciencedirect.com/science/article/pii/S1097276520301581
  48. Jan 2020
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    Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_10695148

      DOI: 10.1016/j.celrep.2019.08.046

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    sciencedirect.com/science/article/pii/S2211124719310940
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    Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS
    1
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      DOI: 10.1016/j.molcel.2019.10.013

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    sciencedirect.com/science/article/pii/S1097276519307919
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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
    1
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      DOI: 10.1016/j.celrep.2019.10.011

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    sciencedirect.com/science/article/pii/S2211124719313117
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 12 Jan 2020
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      DOI: 10.7554/eLife.40364

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344081/
  53. Nov 2018
  54. www.sciencedirect.com www.sciencedirect.com
    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518306750
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    Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module
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    sciencedirect.com/science/article/pii/S0092867418308067
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    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
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    sciencedirect.com/science/article/pii/S1934590917305118
  57. Nov 2017
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    ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
    1
    1. scibot 08 Nov 2017
      AB_10695148

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S153561081730199X