252 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    sciencedirect.com/science/article/pii/S2211124725008137
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    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  4. Jul 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma
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    Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids
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    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer
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    Prostacyclin assists in the repair of ruptured amnions through the proliferation and migration of amnion mesenchymal cells
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    TFE3-splicing factor fusions represent functional drivers and druggable targets in translocation renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/8/1286/742985/TFE3-Splicing-Factor-Fusions-Represent-Functional
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    Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis
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    Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3
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  14. Jun 2025
  15. www.science.org www.science.org
    Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3
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    science.org/doi/10.1126/sciadv.adu8422
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    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    Polybromo 1/vimentin axis dictates tumor grade, epithelial-mesenchymal transition, and metastasis in pancreatic cancer
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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  21. May 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hippo signaling is essential for the maintenance of zona glomerulosa cell fate in the murine adrenal cortex
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1
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    Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity
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  25. Apr 2025
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    Generation of induced pluripotent stem cell lines from five individuals from two families carrying a pathogenic Dutch MYBPC3 founder variant with variable degrees of hypertrophic cardiomyopathy
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  28. Mar 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State
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    Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis
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    ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity
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  33. Feb 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling
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  38. aacrjournals.org aacrjournals.org
    HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA
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    Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages
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    TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma
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  43. Jan 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived tumor organoid and fibroblast assembloid models for interrogation of the tumor microenvironment in esophageal adenocarcinoma
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  46. Dec 2024
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proteomic and functional comparison between human induced and embryonic stem cells
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  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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  50. Nov 2024
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping and tracing Grem1+ stromal cells in an ApcMin/+ mouse utilizing cryopreserved intestinal sections prepared via modified Swiss-roll technique
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    Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
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  55. www.embopress.org www.embopress.org
    JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia
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    embopress.org/doi/10.1038/s44321-024-00166-3
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    Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
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    CircZNF609/miR-324-5p/VDAC1 axis promotes malignant progression of ovarian cancer cells
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  58. Sep 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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  63. Aug 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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  65. Jul 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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  67. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy
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  70. Jun 2024
  71. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma
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  73. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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  74. May 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glial fibrillary acidic protein is pathologically modified in Alexander disease
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    An Orally Efficacious Thyrotropin Receptor Ligand Inhibits Growth and Metastatic Activity of Thyroid Cancers
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    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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  78. Apr 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-associated fibroblasts promote enzalutamide resistance and PD-L1 expression in prostate cancer through CCL5-CCR5 paracrine axis
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    Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling
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    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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    Multicellular ecotypes shape progression of lung adenocarcinoma from ground-glass opacity toward advanced stages
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  83. Mar 2024
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    Autofluorescence is a biomarker of neural stem cell activation state
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    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    Light-mediated intracellular polymerization
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  88. stemcellres.biomedcentral.com stemcellres.biomedcentral.com
    Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis
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    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer
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  91. Feb 2024
  92. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
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    Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer
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    Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
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  96. Jan 2024
  97. dx.doi.org dx.doi.org
    Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells
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  98. Dec 2023
  99. www.sciencedirect.com www.sciencedirect.com
    AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression
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    Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  213. Aug 2021
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  240. Apr 2021
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