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143 Matching Annotations

Sep 2026
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Copper ion-induced MYH9 polymerization executes cuproptosis

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1. scibot 15 Sep 2026
  
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  DOI: 10.1016/j.cell.2026.08.030
  
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sciencedirect.com/science/article/pii/S0092867426010032
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Enhanced neuroprotective effects of combined photobiomodulation and hydrogen inhalation in a mouse model of hypoxic-ischemic brain injury

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1. scibot 11 Sep 2026
  
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  DOI: 10.1007/s00221-026-07352-4
  
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link.springer.com/article/10.1007/s00221-026-07352-4
Aug 2026
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ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway

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1. scibot 15 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.117202
  
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sciencedirect.com/science/article/pii/S2589004226025800
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BPS Publications

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1. scibot 08 Aug 2026
  
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  DOI: 10.1111/bph.15906
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15906
Jul 2026
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Asprosin expression and its role in regulating proliferation, cell cycle, and apoptosis in mouse hippocampal HT-22 cells

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1. scibot 27 Jul 2026
  
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  DOI: 10.1016/j.neuroscience.2026.07.049
  
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sciencedirect.com/science/article/pii/S0306452226004938
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Dual roles of SBSN in renal cancer progression and tumor thrombus: Cell-autonomous NF-κB-CD44 axis and IFI6-driven paracrine angiogenesis

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1. scibot 25 Jul 2026
  
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Targeting KIF11 Degradation: Oxypeucedanin Inhibits Lung Adenocarcinoma Progression by Disrupting the MCM2-CDK1 Signaling Pathway

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1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.phymed.2026.158611
  
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sciencedirect.com/science/article/pii/S0944711326008421
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EZH2 Inhibitors Sensitize Breast Cancer to HER2 Kinase Inhibitors through Cooperative Effects on YAP and Pro-apoptotic Regulators

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-3113
  
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aacrjournals.org/cancerres/article/86/6/1467/775076/EZH2-Inhibitors-Sensitize-Breast-Cancer-to-HER2
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Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma

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1. scibot 09 Jul 2026
  
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Supra-additive neuroprotective effects of berberine–metformin combination in diabetic encephalopathy: Chou–Talalay synergy quantification, AMPK–Nrf2 axis modulation, and pharmacokinetic verification

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1. scibot 07 Jul 2026
  
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Jun 2026
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Suppression of ATM kinase signaling accelerates cellular senescence

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.stemcr.2026.102956
  
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May 2026
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Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice

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1. scibot 29 May 2026
  
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  DOI: 10.1177/15347354261448871
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13201951/
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mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
Apr 2026
54.241.53.176 54.241.53.176

2026.04.20.719456.full-html.html

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1. scibot 30 Apr 2026
  
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  DOI: 10.64898/2026.04.20.719456
  
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54.241.53.176/6790efd246ed84de929dd028ff8d6465bfa7b2e6/2026.04.20.719456.full-html.html
Mar 2026
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A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury

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1. scibot 25 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13006403/
Feb 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226004281-main-html.html

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1. scibot 19 Feb 2026
  
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54.241.53.176/d87d0757cb2189057ec92a05486ad0d385992a97/1-s2.0-S2589004226004281-main-html.html
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Raspberry Polyphenols Target Molecular Pathways of Heart Failure

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1. scibot 04 Feb 2026
  
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  DOI: 10.1016/j.jnutbio.2023.109535
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12862629/
Jan 2026
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CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102526
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12866115/
Dec 2025
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A 3D in vitro model for studying human implantation and implantation failure

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  DOI: 10.1016/j.cell.2025.10.026
  
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sciencedirect.com/science/article/pii/S0092867425012309
Oct 2025
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Cardiomyocyte-specific LARP6 overexpression prevents angiotensin II-induced myocardial dysfunction and interstitial fibrosis

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1. scibot 02 Oct 2025
  
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  DOI: 10.1152/ajpheart.00196.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12482548/
Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225016840-main-html.html

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1. scibot 26 Aug 2025
  
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52.53.155.43/23fa3039143e04e3669aa6d24e522324d4b71ce2/1-s2.0-S2589004225016840-main-html.html
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russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html

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1. scibot 22 Aug 2025
  
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  DOI: 10.6084/m9.figshare.29602265
  
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52.53.155.43/cdc89213e8da95a53f691c27b85c44a7e3f558a7/russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
Jul 2025
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Uric Acid Causes Pancreatic β Cell Death and Dysfunction via Modulating CHOP-Mediated Endoplasmic Reticulum Stress Pathways

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1. scibot 30 Jul 2025
  
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  DOI: 10.3390/diseases13070213
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12293447/
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Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance

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1. scibot 11 Jul 2025
  
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  DOI: 10.1101/2025.06.24.661170
  
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biorxiv.org/content/10.1101/2025.06.24.661170v1
Jun 2025
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Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss

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1. scibot 23 Jun 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0506
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12179588/
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Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity

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  DOI: 10.1124/molpharm.124.000894
  
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PDF-html.html

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  DOI: 10.1016/j.isci.2025.112801
  
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52.53.155.43/0dae8a278297c88adbf334a09a65a2e37332ee1c/PDF-html.html
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PDF-html.html

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1-s2.0-S2589004225011216-main-html.html

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52.53.155.43/2abcfe5fe766e4300373f461f78d375160fe8922/1-s2.0-S2589004225011216-main-html.html
May 2025
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1-s2.0-S2589004225008454-main-html.html

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  DOI: 10.1016/j.isci.2025.112584
  
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Apr 2025
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BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

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  DOI: 10.1158/1078-0432.CCR-24-2548
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
Mar 2025
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The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115462
  
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sciencedirect.com/science/article/pii/S2211124725002335
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Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation

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  DOI: 10.1016/j.bcp.2025.116871
  
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sciencedirect.com/science/article/pii/S0006295225001339
Feb 2025
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Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation

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Slc25a21 in cisplatin-induced acute kidney injury: a new target for renal tubular epithelial protection by regulating mitochondrial metabolic homeostasis

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Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice

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Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy

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Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies

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Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade

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MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels

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Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells

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Apr 2024
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Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome

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Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1

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The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury

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Feb 2024
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Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models

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CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin

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BPS Publications

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Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress

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YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

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Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models

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Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14

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Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX

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ALKBH5-mediated m6A modification of HS3ST3B1-IT1 prevents osteoarthritis progression

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Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

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CCDC50 promotes tumor growth through regulation of lysosome homeostasis

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URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.

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Aug 2023
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PIIS2211124723009543-html.html

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Jun 2023
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METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis

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USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

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Mar 2023
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A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy

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FAM193A is a positive regulator of p53 activity

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Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway

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Feb 2023
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Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux

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Jan 2023
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Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization

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Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

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Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines

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Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways

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The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity

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LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus

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Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression

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Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex

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Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth

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Small molecule SJ572946 activates BAK to initiate apoptosis

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Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis

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Sublethal cytochrome c release generates drug-tolerant persister cells

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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

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Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression

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British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html

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Regulating DNA methylation could reduce neuronal ischemia response and apoptosis after ischemia-reperfusion injury

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Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model

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Jumonji domain-containing protein-3 (JMJD3/Kdm6b) is critical for normal ovarian function and female fertility

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Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide

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Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer

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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

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Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

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The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

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Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation

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Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer

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SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents

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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

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Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species

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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

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ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease

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Untitled document

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Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress

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Andrographolide alleviates parkinsonism in MPTP‐PD mice via targeting DRP1‐mediated mitochondrial fission

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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

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Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

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MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

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Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis

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Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer

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Occludin degradation makes brain microvascular endothelial cells more vulnerable to reperfusion injury in vitro

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BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

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Platelet CLEC‐2 regulates neuroinflammation and restores blood brain barrier integrity in a mouse model of traumatic brain injury

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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

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Sirtuin 3 is required for the protective effect of Resveratrol on Manganese‐induced disruption of mitochondrial biogenesis in primary cultured neurons

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Murine maternal dietary restriction affects neural Humanin expression and cellular profile

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Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner

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Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice

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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

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BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models

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Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM

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NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

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Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Gestational Diabetes Alters Functions in Offspring’s Umbilical Cord Cells With Implications for Cardiovascular Health

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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