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Design, synthesis, and biological evaluation of pyranone–carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.bioorg.2026.109887
  
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sciencedirect.com/science/article/pii/S0045206826004232
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

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1. scibot 10 Sep 2025
  
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  DOI: 10.7554/eLife.104138
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12416886/
May 2025
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Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.027
  
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sciencedirect.com/science/article/pii/S1074761325001906
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A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.bioorg.2025.108551
  
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sciencedirect.com/science/article/pii/S0045206825004316
Mar 2025
journals.lww.com journals.lww.com

The compound... : Neural Regeneration Research

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1. scibot 06 Mar 2025
  
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  DOI: 10.4103/NRR.NRR-D-23-01890
  
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journals.lww.com/nrronline/fulltext/2025/11000/the_compound.34.aspx
Oct 2024
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Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice

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1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.lfs.2024.123085
  
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sciencedirect.com/science/article/pii/S0024320524006751
Feb 2024
www.biorxiv.org www.biorxiv.org

Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis

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1. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.09.570894
  
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2. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.09.570894
  
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biorxiv.org/content/10.1101/2023.12.09.570894v1
Oct 2023
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Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.09.011
  
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sciencedirect.com/science/article/pii/S1534580723005130
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis

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1. scibot 20 Oct 2023
  
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  DOI: 10.4103/1673-5374.379050
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10581551/
May 2023
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Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112529
  
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sciencedirect.com/science/article/pii/S2211124723005405
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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

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1. scibot 06 May 2023
  
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  DOI: 10.1016/j.devcel.2023.04.010
  
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sciencedirect.com/science/article/pii/S1534580723001806
Mar 2022
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Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop

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1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.cub.2022.02.011
  
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sciencedirect.com/science/article/pii/S0960982222002330
Sep 2021
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Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species

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1. scibot 18 Sep 2021
  
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  DOI: 10.1016/j.cmet.2021.08.014
  
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sciencedirect.com/science/article/pii/S1550413121003776
Sep 2020
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Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.04.011
  
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  RRIDCUR:Validated RRID:AB_10696896
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sciencedirect.com/science/article/pii/S1550413120301935
Nov 2018
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Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312818301331